Navigation Links
What water looks like to DNA
Date:11/19/2013

WASHINGTON D.C. Nov. 19, 2013 -- A team of biochemists and mathematicians have developed a sophisticated geometric model to predict how a biological molecule will interact with water molecules, computing the results up to 20 times faster than other existing approaches. This new approach may help researchers find new drugs to treat human diseases, said the team, who described their theoretical approach in the Journal of Chemical Physics, which is produced by AIP Publishing.

"Our research explores how water can change the shape of a molecule, how different molecules can get along well in water and, ultimately, how drug molecules can hit targets with the help of water," says Bo Li, professor of mathematics and senior scientist, National Science Foundation Center for Theoretical Biological Physics, University of California, San Diego.

Biological molecules such as DNA and proteins are the building blocks of living systems, and each molecule consists of many atoms. "How these molecules self-organize is crucial to maintaining a healthy system, because a missing or deformed atom within a molecule can lead to disease," explained Li.

The human body contains numerous biological molecules, many of which are surrounded by water, which can help change their shape and affect how they interact with other molecules in the body. Up to 60 percent of the human body is water, so it's essential that this solvent be considered.

"Many biological molecules are hydrophobic (water repelling), just like a drop of oil in water, but when mixed they will eventually blend together," said Li.

Being able to quickly predict the structure of biological molecules in water by using this new theoretical approach should help improve the ability of researchers to identify new targets and may reduce the need for expensive screening of millions of drug molecules in labs.


'/>"/>

Contact: Jason Socrates Bardi
jbardi@aip.org
240-535-4954
American Institute of Physics
Source:Eurekalert  

Page: 1

Related medicine news :

1. IBWA Video Highlights Importance of Having Bottled Water as a Choice
2. Water and Eye Health Researcher Offers Tips on Coping with Winter “Flu Eyes”
3. Water is the Top Adult Daily Beverage Choice, But Not So Much for Kids and Teens, Reports NPD
4. Restoration Local Seeking Water Damage Repair Contractors To Join Their Network Of Service Provider
5. Eye Strain and Winter Dry Eye Can Increase Stress Reports Water and Eye Researcher
6. Tips from Water and Skin Researcher About How “Pre-Moisturizing” Improves Benefits of Skin Lotion
7. Vets Continue Service Through Local Water and Wastewater Utilities
8. Restoration Local Offers Tips On Emergency Water Damage
9. Lip Balm for Chapped Lips Often Incorrectly Applied Reports Water and Health Researcher
10. Water Select® Raises Funds for Teen with Deadly Brain Cancer Known as Glioblastoma
11. Research and Development Forecast of China’s Water Purifier Industry, 2013-2017
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
What water looks like to DNA
(Date:2/11/2016)... ... , ... According to an article published February 1st on Consumer ... is being recalled due to the discovery that it contains dangerous adulterants. According to ... supplement on the market proven to help people safety lose excess weight, such cases ...
(Date:2/11/2016)... ... February 11, 2016 , ... Florida Hospital presents Heart Health Awareness night ... Louis Blues at the Amalie Arena. The puck drops at 6:00pm, but fans will ... MEGA Heart, prior to the game. The MEGA Heart will be located on Ford ...
(Date:2/11/2016)... , ... February 11, 2016 , ... ... reverse diabetes has been gearing up for their simultaneous grand openings in March. ... about right now that you’re probably wondering, is reversing diabetes possible? According to ...
(Date:2/11/2016)... ... February 11, 2016 , ... veEDIS Clinical ... technology, with highly adaptable algorithms, has been updated to help Emergency Department physicians ... symptoms consistent with Zikas and a travel history to affected regions, or potential ...
(Date:2/11/2016)... Orange City, FL (PRWEB) , ... February 11, ... ... has announced the commencement of a master charity program created to assist the ... every 60 days, working closely with nonprofit organizations and community leaders. Their hope ...
Breaking Medicine News(10 mins):
(Date:2/11/2016)... , Feb. 11, 2016  Governor Andrew M. ... will create 1,400 jobs throughout Western New ... partnership with the SUNY Polytechnic Institute, includes a major ... Building in Buffalo , as well ... manufacturing facility in Dunkirk . The ...
(Date:2/11/2016)... WILMINGTON, N.C. , Feb. 11, 2016 /PRNewswire/ ... a leading provider of custom manufacturing and development ... announces expanded sterile fill-finish capabilities and capacity in ... Substantial growth in demand has driven several recent ... in 2001 it had one filling line with ...
(Date:2/11/2016)... Iowa , Feb. 11, 2016  Proliant Biologicals ... Zealand Bovine Serum Albumin (BSA) manufacturing facility.  The facility ... New Zealand , in Feilding. ... was done to functionally duplicate the systems in the ... same vendors used for U.S. installations.  --> ...
Breaking Medicine Technology: