Navigation Links
What causes hot flushes during menopause?
Date:12/11/2012

ed.

"Rats regulate heat dissipation with their tail because the rest is covered by fur," Rance explained. "In rats without ovaries, the lack of estrogen causes vasodilation, which we can measure as increased tail skin temperature."

"Once we knew that estrogen really does control tail skin temperature in a rat, we wanted to know what role, if any, the KNDy neurons play in this."

When Rance and her team compared the tail skin temperatures of rats with intact KNDy neurons to those with inactivated KNDy neurons, they discovered that while tail skin temperatures still followed the same ups and downs over the course of the day and night cycle, they were lower in the absence of KNDy activity.

"They have lower levels of vasodilation," Rance said. "It is very consistent. Their tail skin temperature is lower than rats with normal KNDy neurons and stays low. It doesn't matter if they have estrogen or not; it doesn't matter if it's night or if it's day."

"The rats didn't seem unhappy at all," she added. "You'd think they'd be curling up and shivering, but no. There was no difference in the core temperature, so they weren't internally cold. We did all the activity measurements and found them to be completely normal. We couldn't tell a difference other than lower vasodilatation."

Rance said she is not surprised that the same neuronal switches that are important for reproduction also control thermoregulation.

"Being able to regulate body temperature is very important for the species and also for reproduction because it is important for a pregnant woman to avoid extreme hyperthermia. Hot flushes are a symptom of hyperactivity of these neurons."

The researchers caution that while KNDy neurons are critical for normal thermoregulation, they are by no means the sole center for managing body temperature.

"These animals would be in much more trouble if that were the case," Mittelman-Smith said. "In fac
'/>"/>

Contact: Daniel Stolte
stolte@email.arizona.edu
520-626-4402
University of Arizona
Source:Eurekalert  

Page: 1 2 3 4

Related medicine news :

1. Demand for One-Stop-Shop Dental Services Causes The Dentists Melbourne to Expand Their Team
2. Gene that causes tumor disorder linked to increased breast cancer risk
3. Seattle Childrens Research Institute helps identify causes of sagittal craniosynostosis
4. Faulty development of immature brain cells causes hydrocephalus
5. LA BioMeds Dr. Richard Casaburi investigates causes of COPD
6. Smoking causes asthma in second generation offspring
7. Key discovered to how chemotherapy drug causes heart failure
8. Tracking environmental causes of good and bad health
9. Staying Home With Sick Kids Causes Job Worries for Parents: Survey
10. In obesity, a micro-RNA causes metabolic problems
11. War causes mental illness in soldiers
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
What causes hot flushes during menopause?
(Date:4/14/2014)... orphaned by HIV/AIDS in South Africa may provide insight ... behavior issues in other areas of the world, which ... that could lead to successful interventions. , A ... United Nations mentions that due to the HIV/AIDS pandemic, ... African, children are at an increased risk for mental ...
(Date:4/14/2014)... A new study shows that moderate to severe ... risk of stroke, cancer and death. , Results of ... to severe obstructive sleep apnea were four times more ... times more likely to have a stroke (HR = ... (HR = 3.4), and 2.5 times more likely to ...
(Date:4/14/2014)... Dallas study involving serious youth offenders, the answer to one ... seven years: "How long do you think you,ll live?", According ... offending over time., Author Dr. Alex Piquero said the study ... of them offend at very high rates and commit more ... much later in life offend much less., "In a lot ...
(Date:4/14/2014)... with symptoms increasing dramatically during some of the most important ... has found. , Depressive symptoms increased on average by 68 ... young men, who were around 25 years old when they ... their children. The results of the study were published April ... is the first to identify when young fathers are at ...
(Date:4/14/2014)... Lower weight babies and babies who aren,t breastfed ... risk of developing chronic inflammation and related health ... study. , "There were good reasons to hypothesize ... inflammation in adulthood," says Thomas McDade (Northwestern University), ... in the Child & Brain Development program. "It ...
Breaking Medicine News(10 mins):Health News:Researchers identify children with emotional behavior difficulties 2Health News:Researchers identify children with emotional behavior difficulties 3Health News:Study links severe sleep apnea to increased risk of stroke, cancer and death 2Health News:UT Dallas study: Youth who fail to envision future commit more crimes 2Health News:Young dads at high risk of depression, too 2Health News:Low birth weight, less breastfeeding create later health risks 2
... , THURSDAY, April 28 (HealthDay News) -- Rising rates ... are cause for concern because excess weight is associated ... says. In people with arthritis, obesity is associated ... life, total joint replacement and poor outcomes after joint ...
... DC (April 28, 2011)Studies have shown that stress can ... against infection and disease. In cancer patients this ... and spread. However, the biological mechanisms that underlie ... Fox Chase Cancer Center find that poor psychosocial functioning ...
... 28 (HealthDay News) -- Use of a costly breast ... by what Medicare will pay for the treatment and ... Researchers analyzed Medicare data for 26,163 women with ... between 2001 and 2005. During that time, Medicare billing ...
... Goodwin HealthDay Reporter , THURSDAY, April 28 ... fill out while waiting to see their child,s ... suggests. Researchers recruited 137 pediatricians in the San ... screening test to fill out before seeing the doctor. ...
... (CTSN) at Emory University are focusing on prairie voles ... drugs to treat autism. They are starting ... behavioral therapy for phobias and also promotes pair bonding ... thought to facilitate learning and memory, can encourage them ...
... 2011 A program which combines interval training and ... those suffering from obesity, according to the results of ... for preventive medicine and physical activity (PIC Centre). Results ... Summit, currently taking place in Montreal. Within the ...
Cached Medicine News:Health News:Rising Obesity Rates Add to Arthritis Woes in U.S. 2Health News:Stress and depression are associated with shorter survival in head and neck cancer patients 2Health News:Payment Rates May Affect Breast Cancer Treatment 2Health News:Quick Screening May Help Spot Autism in Babies 2Health News:Quick Screening May Help Spot Autism in Babies 3Health News:Social bonding in prairie voles helps guide search for autism treatments 2Health News:Social bonding in prairie voles helps guide search for autism treatments 3Health News:Obesity: Conclusive results for the Montreal Heart Institute's EPIC Centre Kilo-Actif program 2
(Date:1/15/2014)... 2014 As health officials across the Midwest ... select Meijer pharmacies in Michigan ... throat to eligible patients, enabling Meijer pharmacists to administer ... under strict protocol set by a physician participating in ... Mich. -based retailer is collaborating with Ferris State ...
(Date:1/15/2014)... , Jan. 15, 2014 Massachusetts ... (NASDAQ: AMGN ) announced today that ... discover and validate new therapeutic targets and develop ... chronic disorder that affects millions worldwide. The MGH-Broad-Amgen ... medicine, IBD biology, human genetics, genomic technology, and ...
(Date:1/15/2014)... 2014  Manufacturers, suppliers and distributors of ... able to protect their most important business ... http://photos.prnewswire.com/prnh/20130716/CL46586LOGO ) Because ... Device Industry, it steadfastly remains one of ... involving IP infringement. This litigious nature can ...
Breaking Medicine Technology:Meijer Pharmacy Offers Free Flu, Strep Testing as Influenza Cases Rise Across the Midwest 2Meijer Pharmacy Offers Free Flu, Strep Testing as Influenza Cases Rise Across the Midwest 3Mass. General, Broad Institute and Amgen Will Work to Discover New Drugs for Inflammatory Bowel Disease 2Mass. General, Broad Institute and Amgen Will Work to Discover New Drugs for Inflammatory Bowel Disease 3Mass. General, Broad Institute and Amgen Will Work to Discover New Drugs for Inflammatory Bowel Disease 4Intellectual Property Insurance for Medical-related Products and Services 2
... for an AI Over Tamoxifen in,a Single Trial ... Analysis of the entire,population of a single trial ... be significantly improved by switching from,tamoxifen to anastrozole ... study, published online in The,Journal of Clinical Oncology, ...
... - Novelos,Therapeutics, Inc. (OTCBB: NVLT), a biopharmaceutical ... treat cancer and,hepatitis, today announced encouraging results ... 2 trial of NOV-002,in combination with carboplatin ... patients were evaluable for best,overall tumor response ...
Cached Medicine Technology:Anastrozole (Arimidex) Improves Overall Survival in Postmenopausal,Women with Early Breast Cancer Receiving Treatment with Tamoxifen 2Anastrozole (Arimidex) Improves Overall Survival in Postmenopausal,Women with Early Breast Cancer Receiving Treatment with Tamoxifen 3Anastrozole (Arimidex) Improves Overall Survival in Postmenopausal,Women with Early Breast Cancer Receiving Treatment with Tamoxifen 4Anastrozole (Arimidex) Improves Overall Survival in Postmenopausal,Women with Early Breast Cancer Receiving Treatment with Tamoxifen 5Novelos Therapeutics Announces Encouraging Results in Ongoing Phase,2 Ovarian Cancer Trial at Dana-Farber/Partners Cancer Care 2Novelos Therapeutics Announces Encouraging Results in Ongoing Phase,2 Ovarian Cancer Trial at Dana-Farber/Partners Cancer Care 3
Latex agglutination inhibition slide test for the qualitative detection of hCG in urine....
Test for the quantitative determination of antideoxyribonuclease-B (ADNase-B) in serum....
Hemagglutination slide test for the qualitative and quantitative detection of Rheumatoid Factor in serum or synovial fluid....
Latex agglutination slide test for the qualitative or semi-quantitative detection of infectious mononucleosis heterophile antibodies in serum or plasma....
Medicine Products: