Navigation Links
What causes hot flushes during menopause?
Date:12/11/2012

just like sweating. Except that if you were to measure core temperature at that point, you would find it is not even elevated."

Although the results are not yet directly applicable in helping individuals affected by hot flushes, they mark a necessary first step, Rance said.

"Obviously we can't do these studies in women, and only if we understand the mechanism is there a chance of developing therapies. All that is known so far is that dwindling estrogen levels have something to do with it but anything after that is a black box."

"Right now the only effective way of treating flushes is estrogen-replacement therapy. If we could figure out what is causing those flushes, we could try to develop a better, more targeted therapy."

Rance said hot flushes usually last for four or five years and occur in up to 80 percent of women but also in men undergoing certain hormone treatments for prostate cancer.

"For some people it's not too bad, but it can be very severe in other individuals; they loose sleep et cetera. So the question I have been asking myself is, 'How come we haven't figured this out?'"

Together with her coworkers, Rance has studied KNDy neurons and their functions for two decades.

"KNDy neurons respond to circulating estrogens," Mittelman-Smith explained. "When these hormones are at very low levels, as is the case in menopause, these neurons go haywire if you will. They grow very large and manufacture several times more neurotransmitter than they did with estrogens present."

"Because the neurons talk to known thermoregulatory centers of the brain, we think this increased signaling activity may inappropriately tell the body, 'I'm hot, release heat.' This triggers heat loss mechanisms like sweating and opening up of blood vessels in the skin."

Analogous to women going through menopause, the tail skin temperature goes up in rats after removal of the ovaries, where estrogen is produc
'/>"/>

Contact: Daniel Stolte
stolte@email.arizona.edu
520-626-4402
University of Arizona
Source:Eurekalert  

Page: 1 2 3 4

Related medicine news :

1. Demand for One-Stop-Shop Dental Services Causes The Dentists Melbourne to Expand Their Team
2. Gene that causes tumor disorder linked to increased breast cancer risk
3. Seattle Childrens Research Institute helps identify causes of sagittal craniosynostosis
4. Faulty development of immature brain cells causes hydrocephalus
5. LA BioMeds Dr. Richard Casaburi investigates causes of COPD
6. Smoking causes asthma in second generation offspring
7. Key discovered to how chemotherapy drug causes heart failure
8. Tracking environmental causes of good and bad health
9. Staying Home With Sick Kids Causes Job Worries for Parents: Survey
10. In obesity, a micro-RNA causes metabolic problems
11. War causes mental illness in soldiers
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
What causes hot flushes during menopause?
(Date:9/18/2014)... Alan Mozes HealthDay Reporter ... it comes to emergency room waiting times, patients seeking care ... staring down the clock than those seen at smaller or ... crowding and our ability to provide timely emergency care varies ... the authors of the new research, Dr. Renee Hsia, an ...
(Date:9/18/2014)... News) -- Daily supplements of selenium or vitamin E ... age-related cataracts among men, a new study indicates. ... could help prevent cataracts. To investigate this further, William ... School in Boston, and his colleagues examined data from ... The trial was initially designed to study prevention of ...
(Date:9/18/2014)... Physicians (CHEST) together with the Chinese Thoracic Society ... CTS that CHEST World Congress 2016 will be ... care, and sleep medicine from around the world ... for spring 2016. , CHEST World Congress ... simulation training, keynote addresses, presentations by leading health-care ...
(Date:9/18/2014)... TayganPoint Consulting Group, a leading strategic ... co-founder John Cassimatis was named as one of ... recognizing the region’s top healthcare and life science ... the year. , The Innovation Awards celebrate companies ... to shape the medical industry in Greater Philadelphia ...
(Date:9/18/2014)... 18, 2014 Qualis Health, one of ... a white paper, “Advancing Primary Care through the ... Technology.” , Authors Jeff Hummel, MD, MPH and ... to organizations engaged in the work of becoming a ... can bolster PCMH objectives, such as generating and providing ...
Breaking Medicine News(10 mins):Health News:ER Waiting Times Vary Significantly, Studies Find 2Health News:ER Waiting Times Vary Significantly, Studies Find 3Health News:Vitamin E, Selenium Supplements Don't Seem to Prevent Cataracts 2Health News:CHEST announces China as site of CHEST World Congress 2016 2Health News:TayganPoint Executive Receives Prestigious Award from Philadelphia Business Journal 2Health News:Advancing Primary Care Through PCMH and HIT: New White Paper Connects the Dots 2
... , , LEAGUE CITY, Texas, ... has been dedicated to the insurance needs of seniors, with an ... insurance Agent. This has never been more evident than in the ... 3, 2009. , , With the advent of ...
... , , , , ... ), a leading provider of kidney care services for those diagnosed ... ranked 39th on the Environmental Protection Agency,s (EPA,s) FORTUNE 500 List ... as the only dialysis provider among the five healthcare companies featured ...
... , , , ATLANTA, Aug. 3 ... waffles with ketchup, kids are willing to eat anything when they get ... among parents, who want to ensure their kids bridge the gap between ... According to a national survey commissioned by frozen snack maker ...
... ... intensive designed specifically to help hospitals and health systems incorporate social media into marketing ... for Sept 16-17, 2009 in Chicago, IL. , ... Norfolk, Virginia (Vocus) - The Strategy Group announces a ...
... DALLAS Aug. 3, 2009 The new anti-wrinkle facial ... Botox, noticeably reduced frown lines between the eyes, according to ... at UT Southwestern Medical Center. "Our study confirmed that ... wrinkles," said Dr. Rod Rohrich, chairman of plastic surgery at ...
... , PT. RICHMOND, Calif., Aug. 2 Transcept Pharmaceuticals, Inc. ... its exclusive license and collaboration agreement with Purdue Pharmaceutical Products L.P. ... United States. The FDA has established October 30, 2009 as the ... ((R)) New Drug Application (NDA). , , ...
Cached Medicine News:Health News:SLAICO Takes the Medicare Supplement Application Online - Eliminating All Paperwork Offline. 2Health News:DaVita Only Dialysis Provider Named on EPA's FORTUNE 500 List of Green Power Purchasers 2Health News:DaVita Only Dialysis Provider Named on EPA's FORTUNE 500 List of Green Power Purchasers 3Health News:Parents Concerned About Kids' After-School Snacking Habits 2Health News:Innovator's Studio offers Social Media Strategy Intensive Sept 16-17, 2009 2Health News:Innovator's Studio offers Social Media Strategy Intensive Sept 16-17, 2009 3Health News:Dysport proves safe, effective anti-wrinkle treatment, UT Southwestern plastic surgeons find 2Health News:Transcept Pharmaceuticals to Hold Conference Call on Agreement with Purdue Pharmaceutical Products L.P. to Commercialize Intermezzo(R) in the United States 2
(Date:9/18/2014)... PLYMOUTH MEETING, Pa. , Sept. 18, ... eClinical trial solutions, was recognized as the ... 2014 for its ePharmaONE cloud-based eClinical platform. ... portal and electronic trial master file (eTMF), ... informed-consent solution, and ePharmaSolutions, ReferralPlus+ patient screening ...
(Date:9/18/2014)... , Sept. 18, 2014   3D Systems   ... the Simbionix RobotiX Mentor™ , a new robotic surgery ... the first time at the ERUS exhibition in ... (booth #7). Robotic-assisted minimally invasive surgery represents a ... means the needs for training for robotic surgery has increased, ...
(Date:9/18/2014)... MELBOURNE, Australia , Sept. 18, 2014 ... appointments of Dr. Ashraf Hanna , M.D., Ph.D., ... its Board of Directors. Dr. Hanna is the Vice ... and Chief Financial Officer for the Genentech Foundation, while ... Global Head of Business Development and Licensing for Roche ...
Breaking Medicine Technology:ePharmaSolutions Named 2014 Disruptive Innovator of the Year for its ePharmaONE eClinical Platform 2ePharmaSolutions Named 2014 Disruptive Innovator of the Year for its ePharmaONE eClinical Platform 33D Systems Introduces New Simbionix Robotics Training Platform 23D Systems Introduces New Simbionix Robotics Training Platform 3Nexvet Appoints Ashraf Hanna and Joseph McCracken to Board of Directors 2Nexvet Appoints Ashraf Hanna and Joseph McCracken to Board of Directors 3
... , CLEVELAND , Feb. ... and services company focused on global eClinical solutions for the ... Annual DIA Workshop in Japan for Clinical Data ... Coates , Vice President of Sales, will participate in the ...
... Feb. 2 PDI, Inc. (Nasdaq: PDII ), a leading ... announced that Chief Executive Officer Nancy Lurker will present at ... February 8-10, 2010 . , The presentation is scheduled for ... take place at The Grand Hyatt New York. , The webcast of ...
Cached Medicine Technology:DATATRAK Attends 13th Annual DIA Workshop in Japan for Clinical Data Management 2DATATRAK Attends 13th Annual DIA Workshop in Japan for Clinical Data Management 3
Fluoroperm 151 lens meets special needs of certain patients who need exceptional oxygen permeability for specific corneal condition or lifestyle requirements....
... Thinsite is designed using sophisticated lathing ... concepts. Thinsite lenses feature a center thickness ... ranges. While all plus powered Thinsite lenses ... over standard designs. The unique design eliminates ...
An easy-to-fit RGP daily wear lens with a unique bi-aspheric back surface design that provides excellent patient comfort and adaptation. Boston Envision contact lenses are an ideal alternative for vi...
Ophthalmic surgery stretcher. Designed for exceptional surgeon access, ideal for either superior or temporal approach....
Medicine Products: