Navigation Links
What causes hot flushes during menopause?
Date:12/11/2012

just like sweating. Except that if you were to measure core temperature at that point, you would find it is not even elevated."

Although the results are not yet directly applicable in helping individuals affected by hot flushes, they mark a necessary first step, Rance said.

"Obviously we can't do these studies in women, and only if we understand the mechanism is there a chance of developing therapies. All that is known so far is that dwindling estrogen levels have something to do with it but anything after that is a black box."

"Right now the only effective way of treating flushes is estrogen-replacement therapy. If we could figure out what is causing those flushes, we could try to develop a better, more targeted therapy."

Rance said hot flushes usually last for four or five years and occur in up to 80 percent of women but also in men undergoing certain hormone treatments for prostate cancer.

"For some people it's not too bad, but it can be very severe in other individuals; they loose sleep et cetera. So the question I have been asking myself is, 'How come we haven't figured this out?'"

Together with her coworkers, Rance has studied KNDy neurons and their functions for two decades.

"KNDy neurons respond to circulating estrogens," Mittelman-Smith explained. "When these hormones are at very low levels, as is the case in menopause, these neurons go haywire if you will. They grow very large and manufacture several times more neurotransmitter than they did with estrogens present."

"Because the neurons talk to known thermoregulatory centers of the brain, we think this increased signaling activity may inappropriately tell the body, 'I'm hot, release heat.' This triggers heat loss mechanisms like sweating and opening up of blood vessels in the skin."

Analogous to women going through menopause, the tail skin temperature goes up in rats after removal of the ovaries, where estrogen is produc
'/>"/>

Contact: Daniel Stolte
stolte@email.arizona.edu
520-626-4402
University of Arizona
Source:Eurekalert  

Page: 1 2 3 4

Related medicine news :

1. Demand for One-Stop-Shop Dental Services Causes The Dentists Melbourne to Expand Their Team
2. Gene that causes tumor disorder linked to increased breast cancer risk
3. Seattle Childrens Research Institute helps identify causes of sagittal craniosynostosis
4. Faulty development of immature brain cells causes hydrocephalus
5. LA BioMeds Dr. Richard Casaburi investigates causes of COPD
6. Smoking causes asthma in second generation offspring
7. Key discovered to how chemotherapy drug causes heart failure
8. Tracking environmental causes of good and bad health
9. Staying Home With Sick Kids Causes Job Worries for Parents: Survey
10. In obesity, a micro-RNA causes metabolic problems
11. War causes mental illness in soldiers
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
What causes hot flushes during menopause?
(Date:8/29/2015)... ... August 30, 2015 , ... On September 30, 2015, the Career and Transfer ... regionally accredited Maricopa Community Colleges , will be hosting a Job Expo to ... information and opportunities. , The Expo has expanded to much more than just a ...
(Date:8/29/2015)... ... August 29, 2015 , ... Targeted therapies, ... improve the lives of patients, according to a newly published report. Surviving Mesothelioma ... the full article. , The authors of the new paper focus on ...
(Date:8/29/2015)... , ... August 29, 2015 , ... ... angina, chronic obstructive pulmonary disease (including emphysema), or asthma, are at higher risk ... angina, previous heart attack, heart failure or heart-rhythm problems (arrhythmia or irregular heartbeat) ...
(Date:8/28/2015)... ... August 28, 2015 , ... ... management, Decatur County Memorial Hospital recently transitioned management companies to partner with Wound ... Management for their outpatient wound center. , Transitioning wound care management providers ...
(Date:8/28/2015)... , ... August 28, 2015 , ... With the goal ... returned for the second year to the Adams County Fairgrounds in Mendon, IL on ... to raise money to support music education in the underfunded school districts of Mendon ...
Breaking Medicine News(10 mins):Health News:Estrella Mountain Community College Expo Offers ‘One-Stop’ for Employers and Students Seeking Internships, Jobs, Careers and Service Learning Opportunities 2Health News:Top Mesothelioma Researchers Highlight Targeted Therapies in New Report, According to Surviving Mesothelioma 2Health News:Heart Fit Clinic Sounds the Alarm on Forest Fire Smoke and Chronic Heart Disease in Calgary Area 2Health News:Decatur County Memorial Hospital Transitions Wound Center Management To Wound Care Advantage and the Luvo Operating System 2Health News:Decatur County Memorial Hospital Transitions Wound Center Management To Wound Care Advantage and the Luvo Operating System 3Health News:Decatur County Memorial Hospital Transitions Wound Center Management To Wound Care Advantage and the Luvo Operating System 4Health News:Best Drug Rehabilitation Interviews Country-Rock Duo Highway Run at the 2015 "Music With A Mission" Benefit Concert 2
... to be created from an egg matured in a laboratory, ... researchers told a medical conference on Monday. ... advanced ovarian disease, and three other women in the 20-person ... ,Doctors already collect and store eggs from women ...
... have found that sleeping under insecticide-treated bed nets might ... ,Most human-to-mosquito transmission originates from adults and children ... of the population and are more attractive to mosquitoes. ... nets for young children and pregnant women in order ...
... Olympics should not be concerned by recent Chinese food ... place for the Games, city officials said. ... building for weeks amid reports of toxic produce endangering ... ,China's own food inspectors announced last week that ...
... by researchers at New York based Columbia University Medical Center ... have had some form of alcohol use disorder at ... per cent of the adults surveyed reported experiencing alcohol abuse, ... background information in an article published in the Archives of ...
... national drink, is on sale for 1,000 pounds a measure. ... the rare Johnnie Walker 1805 has just gone on sale. It ... have been made to celebrate the birthday of the label's founder. ... claim, by the fact the majority of the nine malts used ...
... mountain sickness (AMS), which affects about half of those ascending ... such as pulmonary or cerebral edema. ,The interest of ... over the past 25 years. This change is partly due ... the Internet. In spite of these apparent changes, it is ...
Cached Medicine News:Health News:Infertility Breakthrough With First Birth from Lab-matured Egg 2Health News:Infertility Breakthrough With First Birth from Lab-matured Egg 3Health News:Beijing Says Food Safe for Olympic Athletes, Tourists 2Health News:Beijing Says Food Safe for Olympic Athletes, Tourists 3Health News:One-third of Adults Have Had Some Form of Alcohol Use Disorder During Their Lifetimes 2Health News:Scot's National Drink, Now Available at 1,000 Pounds a Nip 2Health News:Acute Mountain Sickness may Lead to Pulmonary or Cerebral Edema 2
(Date:8/28/2015)... 28, 2015  Perrigo Company plc ("Perrigo") (NYSE: ... the acquisition of leading OTC brands from GSK in ... transaction is a clear demonstration of Perrigo,s unique ability ... distribution network spanning 36 countries.  Perrigo ... commented, "We are excited to complete this transaction, which ...
(Date:8/28/2015)... Massachusetts y LONDRES, 28 de agosto ... AEX: PHIA) anunció hoy su participación en el  ... exhibirá sus soluciones cardiológicas más recientes y novedosas, ... Cardiovascular, que conectan a las personas y la ... de ayudar a diagnosticar, guiar los tratamientos y ...
(Date:8/27/2015)... DURECT Corporation (Nasdaq: DRRX ) announced ... upcoming healthcare conferences.  , James ... the Rodman & Renshaw Investment Conference on Thursday, September ... being held at the St. Regis Hotel in ... webcast of the presentation will be available by accessing ...
Breaking Medicine Technology:Perrigo Completes Acquisition of Leading Portfolio of OTC Brands from GSK 2Perrigo Completes Acquisition of Leading Portfolio of OTC Brands from GSK 3Perrigo Completes Acquisition of Leading Portfolio of OTC Brands from GSK 4Philips presenta nuevas soluciones cardiológicas integradas para desarrollar procedimientos menos invasivos 2Philips presenta nuevas soluciones cardiológicas integradas para desarrollar procedimientos menos invasivos 3Philips presenta nuevas soluciones cardiológicas integradas para desarrollar procedimientos menos invasivos 4Philips presenta nuevas soluciones cardiológicas integradas para desarrollar procedimientos menos invasivos 5DURECT to Participate in Upcoming Healthcare Conferences 2
... Mindray Medical International Limited (NYSE: MR ), ... worldwide, announced today that it will attend the 66th ... between October 31 and November 3, 2011. ... its three primary business segments: patient monitoring and life ...
... Inc. (NASDAQ: MSON ), a medical ... therapeutic ultrasonic products worldwide for wound debridement, spinal ... surgical and medical applications, has announced their recent ... at the International Meeting on Advanced Spine Techniques ...
Cached Medicine Technology:Mindray Medical to Exhibit New Products at 66th China International Medical Equipment Fair 2Mindray Medical to Exhibit New Products at 66th China International Medical Equipment Fair 3Misonix Exhibits BoneScalpel™ at the International Meeting on Advanced Spine Techniques 2Misonix Exhibits BoneScalpel™ at the International Meeting on Advanced Spine Techniques 3
... Now there is a more efficient ... first fully portable battery operated patient ... and surgical teams with a compact ... throughout the entire surgical process. Its ...
... CSZ safely provides effective air warming therapy ... patented design of our WarmAir® FilteredFlo® blankets, ... which supplies gently moving, clean air that ... contaminants to your patient or staff. All ...
Since 1964, in its plants of Sesto Fiorentino, Sbisà produces a wide and qualified range of instruments for ophthalmology and optometry....
Inquire...
Medicine Products: