Navigation Links
What are the Real Benefits Versus Risks of Preventative Brain Radiation for Patients With Non-Small Cell Lung Cancer?
Date:11/2/2009

CHICAGO, Nov. 2 /PRNewswire-USNewswire/ -- Patients with non-small cell lung cancer treated with preventative brain radiation (called prophylactic cranial irradiation or PCI), significantly decrease their risk of developing brain metastases (cancer spread in the brain) by more than 50 percent (from 18 percent to 8 percent), compared to those who did not receive the treatment, according to a randomized study presented at the plenary session November 2, 2009, at the 51st Annual Meeting of American Society for Radiation Oncology (ASTRO).

While there were no significant differences in quality of life, patients who received PCI did have a significantly increased risk of short and long-term memory loss. The study also found that patients who underwent PCI did not live longer than patients who did not receive this treatment.

"This is the first randomized study to analyze neurocognitive and quality of life factors for non-small cell lung cancer patients who undergo PCI," Benjamin Movsas, M.D., presenter of this Radiation Therapy Oncology Group (RTOG) study and chairman of radiation oncology at Henry Ford Hospital in Detroit said. "With better, more targeted treatments, more lung cancer patients are surviving longer and are at increased risk of developing brain metastases. This study provides key information that will lead to a better understanding of the true risks versus benefits of this intervention."

PCI is a preventative type of external beam radiation therapy that treats the entire brain to try to sterilize potential invisible tumor cells that are so small they cannot even be seen on sensitive imaging tests. The risk of cancer developing in the brain increases as people with non-small cell lung cancer are surviving longer due to more effective treatments.

In this study, 340 eligible patients from 127 RTOG institutions with Stage III non-small cell lung cancer whose cancer had not progressed after undergoing treatment were randomized to be treated with PCI or undergo observation from September 2002 to August 2007.

"It's critical for studies to not only report on patient outcomes, such as local control and survival, but also on how the treatments affect the patients, including neurocognition and quality of life factors," Dr. Movsas said. "We need the 'whole picture' in order to be able to accurately assess and discuss treatment options with our patients."

The study was supported by grants from the National Cancer Institute.

For more information on radiation therapy for lung cancer, visit www.rtanswers.org.

The abstract, "Phase III Study of Prophylactic Cranial Irradiation (PCI) versus Observation in Patients with Stage III Non-Small Cell Lung Cancer (NSCLC): Neurocognitive and Quality of Life (QOL) Analysis of RTOG 0214," was presented at the plenary session at 2:15 p.m. on Monday, November 2, 2009. To speak to the presenter of the study, Benjamin Movsas, M.D., please call Beth Bukata or Nicole Napoli November 1-4, 2009, in the ASTRO Press Room at McCormick Place West at 312-791-7005 or 312-791-7006. You may also e-mail them at <u>bethb@astro.or</u><u>g</u> or nicolen@astro.org.

SOURCE American Society for Radiation Oncology


'/>"/>
SOURCE American Society for Radiation Oncology
Copyright©2009 PR Newswire.
All rights reserved

Related medicine news :

1. Practice-based intervention has sustained benefits for children and families
2. Manic phase of bipolar disorder benefits from breast cancer medication
3. Scientists highlight benefits of genetic research in sport, but warn of ethical concerns
4. Smaller breast reduction surgeries provide health benefits and should be reimbursed
5. Cholesterol byproduct blocks heart health benefits of estrogen
6. A Place for Mom, Nations Largest Senior Care Referral Service, Fills a Gap in Employee Benefits
7. New Herbal Water Creating Taste Sensation: Ayalas Herbal Water Has No Calories, No Preservatives and No Artificial Additives. Just All the Natural Benefits of Herbs!
8. Hazards of using crib bumper pads outweigh their benefits
9. Dominium Benefits Experiencing Dynamic Growth
10. The Integrated Benefits Institute Offers Largest Benchmarking Database in U.S. Spanning Disability and Workers Compensation Programs
11. Physiotherapy has short-term benefits for patients after knee surgery
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... Apple ... care services, staged a mock evacuation of the facility as part of a disaster ... Fire Department, Echo Hose EMS and Shelton City Emergency Manager, as well as the ...
(Date:10/13/2017)... , ... October 13, 2017 , ... Global Healthcare Management’s ... Alexandria Park in Milford, NJ. This free event, sponsored by Global Healthcare Management’s ... The fun run is geared towards children of all ages; it is a ...
(Date:10/13/2017)... ... October 13, 2017 , ... “The Journey: From the ... danger possible to save lost souls in the Philippines. “The Journey: From the Mountains ... a dedicated teacher of the Bible. She has taught all ages and currently teaches ...
(Date:10/12/2017)... ... October 12, 2017 , ... Planet Fitness, one of the largest and ... plans to open a flagship location in Covington, LA at 401 N. U.S. Highway ... store next to Office Depot in the Holiday Square shopping center. Its location allows ...
(Date:10/12/2017)... ... 2017 , ... Asante, a nationally recognized health system in ... existing home health joint venture through an agreement, effective October 1, 2017, to ... home health company with Asante, delivering clinically integrated care, for the past eight ...
Breaking Medicine News(10 mins):
(Date:10/10/2017)... -- NDS received FDA 510(k) clearance in May 2017 for its highly ... designed for endoscopy environments. An innovative secondary monitor solution, ZeroWire ... support the improvement of patient outcomes, procedural efficiency, and the lowering ... ... ...
(Date:10/4/2017)... 4, 2017  South Korean-based healthcare product Development Company ... "cprCUBE" on Kickstarter. The device will educate the user ... with better efficiency compared to the dated and pricey ... on efficacy of the compression for a more informed ... goal to raise $5,000. ...
(Date:10/2/2017)... 2017  Eli Lilly and Company (NYSE: ... third quarter of 2017 on Tuesday, October 24, 2017. ... day with the investment community and media to further ... call will begin at 9 a.m. Eastern time. Investors, ... webcast of the conference call through a link that ...
Breaking Medicine Technology: