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Weill Cornell science briefs May 2008
Date:5/14/2008

esbyterian/Weill Cornell, who believes that cancer stem cells may be the cause.

Dr. Boockvar is capturing and classifying these cancer stem cells in order to determine how they react to certain available drug therapies. Doing so will lead to more accurate and specific cancer diagnosis, allowing for tailored drug treatments. Results explaining the techniques used to harvest normal neural and brain-tumor-derived stem cells are described in a recent edition of the journal Neurosurgery.


New Device for Elderly With Heart Valve Failure
Less-Invasive Procedure for Those Previously Untreatable

In the hope of reaching a formerly untreatable patient group, clinician-researchers from NewYork-Presbyterian Hospital/Weill Cornell Medical Center are leading the minimally invasive Phase II EVEREST clinical trial with the aim of treating malfunctioning heart valves in the elderly. Many elderly people are too old, too weak, or too debilitated by their disease to be candidates for traditional surgery to fix the problem, according to Dr. Arash Salemi, attending cardiothoracic surgeon at NewYork-Presbyterian/Weill Cornell, and assistant professor of cardiothoracic surgery at Weill Cornell Medical College. Projections have estimated that by the year 2010, more than 50 million Americans will be over the age of 65. As many of these heart valve diseases occur in older age groups, more and more patients will be in need of therapy each year. And the proportion of high-risk/inoperable patients will also increase. The heart valves are trap doors that control blood flow between the chambers of the heart. With wear, they either become leaky or too tight. Symptoms of these conditions include shortness of breath and fatigue, and if left untreated, may often lead to death by heart failure or arrhythmia.

The new technique, already proven safe by a Phase I clinical trial in 2005, involves only a small incision through the skin in the groin. A smal
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Contact: Andrew Klein
ank2017@med.cornell.edu
212-821-0560
New York- Presbyterian Hospital/Weill Cornell Medical Center/Weill Cornell Medical College
Source:Eurekalert

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