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Weight loss drug helps curb cocaine addictions, Penn study finds
Date:7/18/2013

eavy users also had significantly more negative cocaine drug tests during the trial compared to placebo-treated subjects (17.6 percent vs. 8.8 percent.) The drug likely had a more positive impact on heavy user users because they experience higher levels of cocaine euphoria, said Dr. Kampman.

Sixty-five percent of participants on topiramate stayed in the trial, while 59 percent of subjects on the placebo stayeda statistically significant difference.

"This study further supports topiramate as a promising medication for people who are both alcohol and cocaine dependent," said Dr. Kampman. "Future studies are planned in which topiramate will be combined with other promising medications for the treatment of cocaine dependence in the hope of achieving even higher levels of cocaine abstinence than were achieved with topiramate alone."


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Contact: Steve Graff
stephen.graff@uphs.upenn.edu
215-349-5653
University of Pennsylvania School of Medicine
Source:Eurekalert

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