Navigation Links
Weight-Loss Surgery May Lower Risk of Alzheimer's in Diabetics

SUNDAY, June 5 (HealthDay News) -- While the finding isn't conclusive, a new study suggests that weight-loss surgery in obese diabetics could lower their risk of developing Alzheimer's disease.

Researchers found that gastric bypass patients, when tested six months after their weight-loss surgeries, had less expression of genes that are thought to be precursors of the debris that clogs the brains of people with Alzheimer's disease.

"Our study shows for the first time that weight loss resulting from bariatric surgery leads to a reduction in the expression of genes related to Alzheimer's disease," study author Dr. Paresh Dandona, a professor at State University of New York at Buffalo, said in a news release from the Endocrine Society.

The study was scheduled to be presented Sunday at the society's annual meeting in Boston. Research presented at meetings should be viewed as preliminary because it has not been subjected to the same level of scrutiny as studies published in most medical journals.

In the study, the researchers analyzed the blood of 15 patients with type 2 diabetes who underwent weight-loss surgery and lost an average of about 86 pounds over six months. Compared to before the surgery, the patients' expression of amyloid precursor protein fell by 22 percent, and the researchers also noticed less expression of other genes that appear to be connected to Alzheimer's disease.

However, the study didn't examine the patients for signs of the disease, so there's no way to know if their risk actually went down.

Scientists think there's a link between obesity and diabetes, which appears to boost the risk of Alzheimer's disease, said Greg Cole, associate director of the Alzheimer's Center at the University of California, Los Angeles. He said obesity may boost inflammation in both the body and the brain.

"Weight loss is likely to improve health, but one caveat is that the epidemiology of weight loss is complicated," he added. "Weight loss in elderly people can be a harbinger of incipient dementia. Further, according to a National Institute on Aging study, there may be significant differences in the way in which changes in mid-life weight impact the risk for Alzheimer's: women who lose weight between 30 and 45 actually appear to be at increased risk."

More information

For more about Alzheimer's disease, visit the U.S. National Library of Medicine.

-- Randy Dotinga

SOURCES: Greg Cole, Ph.D., associate director, Alzheimer's Center, University of California, Los Angeles; Endocrine Society, news release, June 5, 2011

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Weight-Loss Surgery Linked to Rise in Fracture Risk
2. Private weight-loss surgery clinics shedding quality patient care
3. Weight-Loss Surgery Seems No Riskier for Seniors
4. Weight-loss counseling most prevalent between male physicians and obese men
5. Experimental Weight-Loss Drug Seems to Work: Study
6. Could Stomach Pacemaker Be New Weight-Loss Tool?
7. Weight-Loss Surgery May Cut Migraine Pain in Obese Patients
8. Benefits of Weight-Loss Surgery May Outweigh Risks for Some, Experts Say
9. Weight-loss surgery successful in treating overweight adolescents
10. Weight-Loss Surgery May Remodel Heart
11. Weight-Loss Surgery May Ease Incontinence in Women
Post Your Comments:
Related Image:
Weight-Loss Surgery May Lower Risk of Alzheimer's in Diabetics 
(Date:11/27/2015)... ... November 27, 2015 , ... Keeping in mind challenges faced ... and wellness consultation, has collaborated with a leading web-based marketplace for extra-curricular activities ... by parents and bring advice from parenting experts within their reach. As a ...
(Date:11/27/2015)... (PRWEB) , ... November 27, 2015 , ... Avid collector, ... Ann Arbor Michigan boxing style concert posters. This is one of Joplin's most famous ... Canterbury House at the University of Michigan in Ann Arbor. The According to Hawley, ...
(Date:11/26/2015)... Cambridge, ON (PRWEB) , ... November 26, 2015 ... ... availability of a real-time eReferral system for diagnostic imaging in the Waterloo region. ... mammography, BMD and Nuclear Medicine tests directly from their electronic medical record (EMR) ...
(Date:11/26/2015)... ... November 26, 2015 , ... PRMA Plastic Surgery is ... 2015, our surgeons performed their 6,000th free flap breast reconstruction surgery! , “What an ... every day excited to rebuild lives and it’s an honor to have served all ...
(Date:11/26/2015)... ... November 26, 2015 , ... Indosoft Inc., developer and distributor of the world-class ... improve system efficiency and reliability. , The new Q-Suite 6 platform is based on ... avoids locking itself into a specific piece of software for many key components of ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... 26, 2015 ... ser potential att använda SyMRI för att ... för patienter med multipel skleros (MS) eller ... SyntheticMR AB för att kunna använda SyMRI ... Med SyMRI kan man generera flera konstrastbilder ...
(Date:11/26/2015)... November 26, 2015 ... adds "Global Repaglinide Industry ... Report on China Repaglinide Market, 2010-2019" ... data and information to its online ... . --> ...
(Date:11/26/2015)... 2015 ) ... "Radioimmunoassay Market by Type (Reagents & Kits, ... Clinical Diagnostic Labs), Application (Research, Clinical Diagnostics), ... report to their offering. --> ... of the "Radioimmunoassay Market by Type ...
Breaking Medicine Technology: