Navigation Links
Weight-Loss Surgery May Lower Risk of Alzheimer's in Diabetics

SUNDAY, June 5 (HealthDay News) -- While the finding isn't conclusive, a new study suggests that weight-loss surgery in obese diabetics could lower their risk of developing Alzheimer's disease.

Researchers found that gastric bypass patients, when tested six months after their weight-loss surgeries, had less expression of genes that are thought to be precursors of the debris that clogs the brains of people with Alzheimer's disease.

"Our study shows for the first time that weight loss resulting from bariatric surgery leads to a reduction in the expression of genes related to Alzheimer's disease," study author Dr. Paresh Dandona, a professor at State University of New York at Buffalo, said in a news release from the Endocrine Society.

The study was scheduled to be presented Sunday at the society's annual meeting in Boston. Research presented at meetings should be viewed as preliminary because it has not been subjected to the same level of scrutiny as studies published in most medical journals.

In the study, the researchers analyzed the blood of 15 patients with type 2 diabetes who underwent weight-loss surgery and lost an average of about 86 pounds over six months. Compared to before the surgery, the patients' expression of amyloid precursor protein fell by 22 percent, and the researchers also noticed less expression of other genes that appear to be connected to Alzheimer's disease.

However, the study didn't examine the patients for signs of the disease, so there's no way to know if their risk actually went down.

Scientists think there's a link between obesity and diabetes, which appears to boost the risk of Alzheimer's disease, said Greg Cole, associate director of the Alzheimer's Center at the University of California, Los Angeles. He said obesity may boost inflammation in both the body and the brain.

"Weight loss is likely to improve health, but one caveat is that the epidemiology of weight loss is complicated," he added. "Weight loss in elderly people can be a harbinger of incipient dementia. Further, according to a National Institute on Aging study, there may be significant differences in the way in which changes in mid-life weight impact the risk for Alzheimer's: women who lose weight between 30 and 45 actually appear to be at increased risk."

More information

For more about Alzheimer's disease, visit the U.S. National Library of Medicine.

-- Randy Dotinga

SOURCES: Greg Cole, Ph.D., associate director, Alzheimer's Center, University of California, Los Angeles; Endocrine Society, news release, June 5, 2011

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Weight-Loss Surgery Linked to Rise in Fracture Risk
2. Private weight-loss surgery clinics shedding quality patient care
3. Weight-Loss Surgery Seems No Riskier for Seniors
4. Weight-loss counseling most prevalent between male physicians and obese men
5. Experimental Weight-Loss Drug Seems to Work: Study
6. Could Stomach Pacemaker Be New Weight-Loss Tool?
7. Weight-Loss Surgery May Cut Migraine Pain in Obese Patients
8. Benefits of Weight-Loss Surgery May Outweigh Risks for Some, Experts Say
9. Weight-loss surgery successful in treating overweight adolescents
10. Weight-Loss Surgery May Remodel Heart
11. Weight-Loss Surgery May Ease Incontinence in Women
Post Your Comments:
Related Image:
Weight-Loss Surgery May Lower Risk of Alzheimer's in Diabetics 
(Date:6/25/2016)... ... June 25, 2016 , ... On Friday, June 10, ... Bronze Wellness at Work award to iHire in recognition of their exemplary accomplishments in ... the 7th annual Maryland Workplace Health & Wellness Symposium at the BWI Marriott in ...
(Date:6/24/2016)... ... June 24, 2016 , ... June 19, 2016 is World Sickle ... chronic pain and the benefits of holistic treatments, Serenity Recovery Center of ... Sickle Cell Disease. , Sickle Cell Disease (SCD) is a disorder of the red ...
(Date:6/24/2016)... Francisco, CA (PRWEB) , ... June 24, 2016 ... ... CitiDent, is now offering micro-osteoperforation for accelerated orthodontic treatment. Dr. Cheng has extensive ... self-ligating Damon brackets , AcceleDent, and accelerated osteogenic orthodontics. , Micro-osteoperforation ...
(Date:6/24/2016)... ... June 24, 2016 , ... EB Medicine ... Making in Emergency Medicine conference in Ponte Vedra Beach, FL. The awards honor ... Emergency Medicine Practice and Pediatric Emergency Medicine Practice. , “With this ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... National recruitment ... a life sciences executive with extensive sequencing and genomics experience, as Vice President of ... position, Ms. Hill will be responsible for leading the sales team in the commercialization ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... , , , WHEN: ... , , , , LOCATION: , , , Online, with ... , EXPERT PANELISTS:  , , , Frost & Sullivan,s Global Vice ... Senior Industry Analyst, Divyaa Ravishankar and Unmesh Lal, Program Manager , ... industry is witnessing an exceptional era. Several new demand spaces, such ...
(Date:6/23/2016)... Revolutionary technology includes multi-speaker listening ... industry leaders in advanced audiology and hearing aid technology, ... ™, the world,s first internet connected hearing aid that ...      (Photo: ) , ... ,world firsts,: , TwinLink™ - the first ...
(Date:6/23/2016)... 23, 2016 Research and Markets ... Volumes: Global Analysis (United States, China, Japan, Brazil, United ... to their offering. ... healthcare business planners, provides surgical procedure volume data in ... with an in-depth analysis of growth drivers and inhibitors, ...
Breaking Medicine Technology: