Navigation Links
Weight-Loss Surgery May Lower Risk of Alzheimer's in Diabetics
Date:6/5/2011

SUNDAY, June 5 (HealthDay News) -- While the finding isn't conclusive, a new study suggests that weight-loss surgery in obese diabetics could lower their risk of developing Alzheimer's disease.

Researchers found that gastric bypass patients, when tested six months after their weight-loss surgeries, had less expression of genes that are thought to be precursors of the debris that clogs the brains of people with Alzheimer's disease.

"Our study shows for the first time that weight loss resulting from bariatric surgery leads to a reduction in the expression of genes related to Alzheimer's disease," study author Dr. Paresh Dandona, a professor at State University of New York at Buffalo, said in a news release from the Endocrine Society.

The study was scheduled to be presented Sunday at the society's annual meeting in Boston. Research presented at meetings should be viewed as preliminary because it has not been subjected to the same level of scrutiny as studies published in most medical journals.

In the study, the researchers analyzed the blood of 15 patients with type 2 diabetes who underwent weight-loss surgery and lost an average of about 86 pounds over six months. Compared to before the surgery, the patients' expression of amyloid precursor protein fell by 22 percent, and the researchers also noticed less expression of other genes that appear to be connected to Alzheimer's disease.

However, the study didn't examine the patients for signs of the disease, so there's no way to know if their risk actually went down.

Scientists think there's a link between obesity and diabetes, which appears to boost the risk of Alzheimer's disease, said Greg Cole, associate director of the Alzheimer's Center at the University of California, Los Angeles. He said obesity may boost inflammation in both the body and the brain.

"Weight loss is likely to improve health, but one caveat is that the epidemiology of weight loss is complicated," he added. "Weight loss in elderly people can be a harbinger of incipient dementia. Further, according to a National Institute on Aging study, there may be significant differences in the way in which changes in mid-life weight impact the risk for Alzheimer's: women who lose weight between 30 and 45 actually appear to be at increased risk."

More information

For more about Alzheimer's disease, visit the U.S. National Library of Medicine.

-- Randy Dotinga

SOURCES: Greg Cole, Ph.D., associate director, Alzheimer's Center, University of California, Los Angeles; Endocrine Society, news release, June 5, 2011


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Weight-Loss Surgery Linked to Rise in Fracture Risk
2. Private weight-loss surgery clinics shedding quality patient care
3. Weight-Loss Surgery Seems No Riskier for Seniors
4. Weight-loss counseling most prevalent between male physicians and obese men
5. Experimental Weight-Loss Drug Seems to Work: Study
6. Could Stomach Pacemaker Be New Weight-Loss Tool?
7. Weight-Loss Surgery May Cut Migraine Pain in Obese Patients
8. Benefits of Weight-Loss Surgery May Outweigh Risks for Some, Experts Say
9. Weight-loss surgery successful in treating overweight adolescents
10. Weight-Loss Surgery May Remodel Heart
11. Weight-Loss Surgery May Ease Incontinence in Women
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Weight-Loss Surgery May Lower Risk of Alzheimer's in Diabetics 
(Date:12/8/2016)... ... 08, 2016 , ... The Florida Hospital Tampa Wound Healing ... Society (UHMS), the leading authority in hyperbaric medicine. This accreditation identifies the Institute ... and facilities have earned this distinction. This is the second time the Florida ...
(Date:12/8/2016)... JENNERSVILLE, Pa. (PRWEB) , ... December 08, 2016 ... ... Penn Medicine Southern Chester County, a Property owned by an affiliate of Seavest, ... 72,000 square foot Penn Medicine Southern Chester County ambulatory care center (ACC) was ...
(Date:12/8/2016)... ... December 08, 2016 , ... David J. Dykeman ... law firm Greenberg Traurig, LLP, will speak at DeviceTalks West, Dec. 12, 2016, at ... DeviceTalks series, and attorneys from the firm’s global Life Sciences & Medical Technology Group ...
(Date:12/8/2016)... ... December 08, 2016 , ... ... development solutions for drugs, biologics and consumer health products, today announced that it ... up in 2006 as a non-profit organization to unite pharmaceutical and healthcare companies ...
(Date:12/8/2016)... City, Ga (PRWEB) , ... December 08, 2016 ... ... moving as soon after surgery as possible. With this in mind, SIGVARIS has ... thrombosis (DVT or blood clot) during bed rest and provide the benefits of ...
Breaking Medicine News(10 mins):
(Date:12/9/2016)... aTyr Pharma, Inc. (Nasdaq: LIFE ), a biotherapeutics company ... severe, rare diseases, today announced that senior management will participate in ... Conference at the InterContinental Barclay Hotel in New York ... ET. About aTyr Pharma ... aTyr Pharma is engaged in the ...
(Date:12/9/2016)... , Dec. 9, 2016  Forge Therapeutics, Inc. ... (Frankfurt Stock Exchange: EVT, TecDAX, ISIN: DE0005664809) to ... for the treatment of bacterial infections including those ... recognized as an attractive antibacterial target for more ... of suitable chemical starting points has hampered its ...
(Date:12/8/2016)... -- The global biosurgery market is expected to grow at ... 2016 to 2021. The market is poised to reach ... in 2016. The market is primarily driven by rising ... and spinal problems, increasing clearance of biosurgery products by ... management. In this report, the biosurgery market ...
Breaking Medicine Technology: