Navigation Links
Weight Loss Might Ease Psoriasis, Study Hints
Date:5/29/2013

By Dennis Thompson
HealthDay Reporter

WEDNESDAY, May 29 (HealthDay News) -- People with psoriasis who lose weight could experience some relief from the symptoms of their chronic skin disease, according to a small new study.

A clinical trial based in Denmark found that obese patients with psoriasis who lost weight through a low-calorie diet experienced a significant improvement in their quality of life, compared to obese psoriasis patients who didn't lose weight.

The patients in the weight-loss group reported less stinging and burning, were less likely to be embarrassed by unsightly lesions, and found that their condition affected their everyday life less often, said Dr. Peter Jensen, of the Copenhagen University Hospital Gentofte, and colleagues.

"Our results emphasize the importance of weight loss as part of a multimodal treatment approach to effectively treat both the skin condition and its [related medical] conditions in overweight patients with psoriasis," the researchers said in the study, which was published online May 29 in the journal JAMA Dermatology.

Psoriasis is a chronic inflammatory skin disease that develops when a person's immune system malfunctions and causes skin cells to grow too quickly. The new skin cells form in days rather than weeks and pile up on the skin's surface, causing scaly, painful lesions.

In the randomized clinical trial, 27 patients were assigned to an intervention group that followed a low-calorie diet and 26 patients were assigned to a control group that continued to eat ordinary healthy foods. Researchers tracked psoriasis symptoms and quality of life using two questionnaires.

The patients on a low-calorie diet ended up losing nearly 34 pounds in 16 weeks, and reported improvements in both their psoriasis symptoms and their overall quality of life.

Dermatologists said the study's results are not surprising, but do reinforce the need for overweight or obese people with psoriasis to try to lose weight.

"Obesity is a huge issue for patients with psoriasis," said Dr. Joel Gelfand, an associate professor of dermatology and medical director of the clinical studies unit at the Hospital of the University of Pennsylvania, in Philadelphia. "If you're obese with psoriasis, psoriasis is less likely to get clear."

There are a couple reasons excess weight can exacerbate a person's psoriasis. First, psoriasis is an inflammatory disease, and obesity is a known cause of inflammation, said Dr. Larry Green, chairman of the research committee for the National Psoriasis Foundation.

"Anytime someone is obese, it's going to affect how their body can heal because it's a stress on the body and stress affects inflammation," Green said. "By losing weight, they're going to reduce the burden on their body."

Another possibility is that obesity may cause immune system responses that are very similar to those prompted by psoriasis.

"Obesity is associated with the same elevations of cytokines in the blood that promote psoriasis," Gelfand said. Cytokines are small signaling proteins used to regulate the body's immune response.

On a more mundane level, obesity also causes skin friction as parts of the body rub against each other, another expert said.

"If skin rubs against skin, psoriasis gets worse," said Dr. Jeffrey Weinberg, a dermatologist at Beth Israel Medical Center in New York City. "Friction makes psoriasis get worse."

Gelfand said it's difficult to draw major clinical conclusions from such a small pilot study, adding that the people in the Danish study suffered from mild to moderate psoriasis and therefore were less likely to experience a vast improvement in their symptoms from weight loss.

"Larger studies in a population of patients with more severe skin disease are necessary to determine if these findings are clinically important," he said.

More information

The American Academy of Dermatology has more about psoriasis.

SOURCES: Joel Gelfand, M.D., associate professor of dermatology, and medical director, clinical studies Hospital of the University of Pennsylvania, Philadelphia; Larry Green, M.D., chairman, research committee, National Psoriasis Foundation; Jeffrey Weinberg, M.D, dermatologist, Beth Israel Medical Center, New York City; May 29, 2013, JAMA Dermatology, online


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Tree nut consumption associated with lower body weight and lower prevalence of health risks
2. Even Preschoolers View the Overweight Negatively
3. Weight-Loss Surgery Beat Drugs for Cutting Diabetes in Very Obese
4. Overweight Pregnant Women at Higher Risk for Complications
5. Can weight loss help African-American breast cancer survivors?
6. Guidelines say diet, exercise, weight control improve odds after cancer diagnosis
7. Slow-growing babies more likely in normal-weight women; Less common in obese pregnancies
8. Healthy Weight Loss May Also Cut Your Cancer Risk
9. In Moms Eyes, Overweight Toddler May Not Be
10. IUD Use Tied to Modest Weight Loss
11. Study: Kids Who Sleep in Parents Bed Less Likely to Be Overweight
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Weight Loss Might Ease Psoriasis, Study Hints
(Date:6/25/2016)... , ... June 25, 2016 , ... On Friday, June ... a Bronze Wellness at Work award to iHire in recognition of their exemplary accomplishments ... of the 7th annual Maryland Workplace Health & Wellness Symposium at the BWI Marriott ...
(Date:6/24/2016)... ... 24, 2016 , ... June 19, 2016 is World Sickle Cell Observance Day. ... the benefits of holistic treatments, Serenity Recovery Center of Marne, Michigan, has ... , Sickle Cell Disease (SCD) is a disorder of the red blood cells, which ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... for accelerated orthodontic treatment. Dr. Cheng has extensive experience with all areas of ... AcceleDent, and accelerated osteogenic orthodontics. , Micro-osteoperforation is a revolutionary adjunct to ...
(Date:6/24/2016)... , ... June 24, 2016 , ... ... at the Clinical Decision Making in Emergency Medicine conference in Ponte Vedra Beach, ... journal articles published in Emergency Medicine Practice and Pediatric Emergency Medicine ...
(Date:6/24/2016)... ... ... National recruitment firm Slone Partners is pleased to announce the ... as Vice President of North American Capital Sales at HTG Molecular . ... team in the commercialization of the HTG EdgeSeq system and associated reagents in North ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... , Belgium , June 24, ... VNRX), today announced the appointment of Dr. ... Directors as a Non-Executive Director, effective June 23, ... Audit, Compensation and Nominations and Governance Committees.  As ... Futcher will provide independent expertise and strategic counsel ...
(Date:6/23/2016)... 23, 2016 Any dentist who has made an ... current process. Many of them do not even offer this ... and high laboratory costs involved. And those who ARE able ... such a high cost that the majority of today,s patients ... Parsa Zadeh , founder of Dental Evolutions Inc. and ...
(Date:6/23/2016)... , June 23, 2016 Research and ... Devices Medical Market Analysis 2016 - Forecast to 2022" ... The report contains up to date financial data derived ... Assessment of major trends with potential impact on the market ... of market segmentation which comprises of sub markets, regional and ...
Breaking Medicine Technology: