Navigation Links
Weight-Loss Enzyme Identified
Date:7/22/2009

Researchers may have found a way to curb hunger, rev up energy

TUESDAY, July 21 (HealthDay News) -- Reducing levels of a brain enzyme may curb appetite and boost energy, thereby helping people to control their weight, says a new study.

Prolylcarboxypeptidase (PRCP) regulates the alpha-melanocyte stimulating hormone (alpha-MSH), a body chemical that reduces hunger while revving up the body's energy levels. If PRCP enzyme is blocked, alpha-MSH levels stay high and keep appetite in check.

When researchers at Yale School of Medicine in New Haven, Conn., blocked PRCP in mice, the rodents lost weight, maintained their energy levels and reduced their risk of developing type 2 diabetes, the team reported in the August issue of the Journal of Clinical Investigation.

Even after the mice ate a high-fat diet designed to simulate eating fast-food every day, the PRCP-blocked mice gained less weight than normal mice on a regular diet.

"Our research provides the first evidence that breaking down molecules in the brain that regulate metabolism is an important component of weight control," senior author Sabrina Diano, associate professor in Yale's departments of obstetrics, gynecology and reproductive sciences, and neurobiology, said in a news release from the university.

"Our findings provide a possible new target for the development of drugs to control metabolic disorders such as obesity and type 2 diabetes," she added.

The researchers next plan to study how the body regulates PRCP, she said.

More information

The American Diabetes Association has more about type 2 diabetes.



-- Kevin McKeever



SOURCE: Yale University, news release, July 20, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Page: 1

Related medicine news :

1. Jillian Michaels, Americas Toughest Trainer, Announces New Line of Weight-Loss Supplements
2. Obese Poor Shut Out From Weight-Loss Surgeries
3. Weight-Loss Surgery Safe, Effective Type 2 Diabetes Treatment
4. Common Weight-Loss Surgery May Double Risk of Kidney Stones
5. Might Weight-Loss Surgery Lead to Fractures?
6. Weight-Loss Surgery Options Compared in Super-Obese
7. Weight-Loss Surgery Simplified
8. Dr. Adam Smith Chosen to Help Introduce No-Scar Surgical Weight-Loss Innovations
9. Dr. Siegals Cookie Diet Book by Physician, Author, and Weight-Loss Expert Sanford Siegal, D.O., M.D., Available May 22nd
10. Losing the Last Ten Pounds is the Hardest Part of any Diet Confirms Weight-Loss Expert and Author Dr. Sanford Siegal
11. Revolutionary Weight-Loss Center Opens in Pikesville
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Weight-Loss Enzyme Identified
(Date:10/13/2017)... ... October 13, 2017 , ... Yisrayl Hawkins, Pastor and ... explains one of the most popular and least understood books in the Holy Scriptures, ... puzzling descriptions that have baffled scholars for centuries. Many have tossed it off as ...
(Date:10/13/2017)... ... October 13, 2017 , ... ... Software Development, has been awarded a contract by the Center for Medicare and ... aims to accelerate the enterprise use of Agile methodologies in a consistent and ...
(Date:10/13/2017)... , ... October 13, 2017 , ... “America On The ... identity. “America On The Brink” is the creation of published author, William Nowers. ... great-grandchildren. As a WWII veteran, he spent thirty years in the Navy. ...
(Date:10/12/2017)... CA (PRWEB) , ... October 12, 2017 , ... ... Cheng, are now treating sleep apnea using cutting-edge Oventus O2Vent technology. ... a serious sleep disorder characterized by frequent cessation in breathing. Oral appliances can ...
(Date:10/12/2017)... ... October 12, 2017 , ... The ... demand of today’s consumer and regulatory authorities worldwide. From Children’s to Adults 50+, ... to meet the highest standard. , These products are also: Gluten Free, ...
Breaking Medicine News(10 mins):
(Date:10/5/2017)... , Oct. 5, 2017  In response ... of Oral and Maxillofacial Surgeons (AAOMS) released prescribing ... – to be used as a first-line therapy ... Recognizing the ... AAOMS White Paper "Opioid Prescribing: Acute and Postoperative ...
(Date:10/2/2017)... Diplomat Pharmacy, Inc. (NYSE: DPLO ... LLC , and named its founder as Diplomat,s chief ... Tennessee , will operate under Diplomat subsidiary ... offerings for health care partners to include IT outsourcing, ... "In an interoperable world, technology delivers comprehensive insight ...
(Date:10/2/2017)... 2017 The Rebound mobile app is poised to ... the tide of prescription drug addiction. The app empowers users ... and stepping down their dosage in a safe, controlled manner ... 2017; the first 100,000 people to sign up will enjoy ... ...
Breaking Medicine Technology: