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Weekly dose reduces targeted drug's side effects, but not its activity against ALL
Date:12/11/2012

ade 3-4 liver elevations."

O'Brien added that a new trial at MD Anderson is incorporating the antibody with low-dose chemotherapy as a frontline regimen for ALL in patients over age 65.

"One of the biggest complications in treating older patients with ALL is that the treatments cause myelosuppression, which makes patients more vulnerable to infection, and older patients are particularly susceptible to this and other complications," she said. "The idea is to take a very well-tolerated antibody and combine it with chemotherapy. That way we might not have to use full-dose chemo and can reduce side effects."


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Contact: Scott Merville
smerville@mdanderson.org
713-516-4855
University of Texas M. D. Anderson Cancer Center
Source:Eurekalert  

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Weekly dose reduces targeted drug's side effects, but not its activity against ALL
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