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Weather, stomach bugs and climate change: Refining the model
Date:6/4/2008

BOSTON (June 4, 2008) Monitoring extreme weather, such as periods of high temperature, is one way to predict the timing and intensity of infectious diseases like cryptosporidiosis, an intestinal disease that causes upset stomach and diarrhea. Two public health researchers have created a model that takes into account weather and other factors that affect the number of people who will fall ill during an outbreak. With this model they show that the risk of weather-sensitive diseases may increase with climate variability or even gradual climate change. Better understanding of the ways in which climate can affect disease will help researchers forecast infectious disease outbreaks and design early warning systems.

In a paper published in Environmetrics, first author Elena Naumova, PhD, associate professor in the Department of Public Health and Family Medicine at Tufts University School of Medicine in Boston and co-author Ian MacNeill, PhD, professor emeritus, in the Department of Statistics & Actuarial Sciences at the University of Western Ontario, introduce a model that takes into consideration the lag time between exposure and infection. The authors then demonstrate this model by analyzing the association between high temperature and daily incidence of cryptosporidiosis in Massachusetts from 1996-2001.

In this new model, Naumova and MacNeill consider several factors: outdoor temperature, base level of a disease in a community before an outbreak, the number of people infected throughout the course of the outbreak, and incubation time of a given disease. "It is this last factor that affects what we call the lag time," says Naumova, "infected individuals go on to infect others, and current models may be underestimating the number of cases in an outbreak by failing to account for lag time."

"To consider such time-distributed lags is a challenging task given that the length of a latent period varies from hours to months and depends on the ty
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Contact: Siobhan Gallagher
617-636-6586
Tufts University, Health Sciences
Source:Eurekalert

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