Navigation Links
Wayne State therapeutic marijuana use study could impact state policies, guide treatment
Date:11/3/2011

A $1.5 million grant to a Wayne State University researcher from the National Institute on Drug Abuse of the National Institutes of Health could have policy implications in Michigan and other states regarding the therapeutic use of marijuana.

Mark Greenwald, Ph.D., professor of psychiatry and behavioral neurosciences in the School of Medicine and director of the Substance Abuse Research Division, is seeking to understand the differences in marijuana use between three subgroups. Drawn from a pool of 1,800 HIV-positive patients in the WSU HIV clinic, the groups include those who are certified by the state to use marijuana for therapeutic reasons; those who are not certified but report using it at least occasionally for biological reasons such as nausea, pain relief and appetite stimulation; and those who use it only recreationally.

Greenwald prefers the term "therapeutic" to "medical" marijuana because doctors under federal law are prevented from actually prescribing it for their patients. The U.S. Food and Drug Administration does not list marijuana as having a medical use, but under laws in Michigan and some other states, doctors can certify that marijuana use may be beneficial to patients with particular conditions, one of which is HIV/AIDS.

"Implementation of state laws that allow therapeutic marijuana use including the Michigan Medical Marihuana Program (MMMP) create a significant policy problem because we lack systematic scientific data concerning factors that influence use patterns, abuse potential, decisions to seek or renew medical certification, impact of marijuana use on HIV transmission behaviors and health outcomes," Greenwald said. "Our overall goal is to address these knowledge gaps."

He will conduct two studies. The first, to begin later this year, will involve 150 marijuana-users living with HIV or AIDS.

Fifty will be certified therapeutic users, defined as having valid MMMP registration within the prior three months. Another 50 will be noncertified therapeutic users, those who self-reported marijuana use to alleviate symptoms at least once during the prior three months. The third group will comprise recreational users with no self-reported symptom self-medication during the prior three months.

Greenwald will use behavioral economic simulations to evaluate the sensitivity of patients' marijuana demand to experimental manipulation of unit price and income. He also will determine whether the three groups differ in their use as a function of price, in the relationship between marijuana price and demand for other drugs or therapies, and in the relationship between income and marijuana or other drug use.

"All of these are things that economists would be interested in," Greenwald said. "A lot of policy derives from economic considerations."

Data will be collected at baseline and at quarterly intervals for one year afterward. It will include clinical factors that may influence marijuana use and certification, such as socioeconomic changes; physical and mental health; substance use; criminal involvement; acute care utilization; and HIV risk-transmission behaviors. Clinical data will be used alone, as well as combined with simulated marijuana demand, to predict longitudinal patterns of marijuana and alternative therapy use.

In the second study, researchers will randomly survey 300 of the HIV clinic's 1,800 patients to determine whether patterns of marijuana use in the 150-patient prospective sample can be generalized to the entire clinic.

Researchers will try to determine whether such patterns within a large urban clinic in an area with disproportionally high HIV prevalence are representative of the rest of the country. They also will compare sample characteristics to prior cross-sectional survey data that have been reported outside the United States.

Greenwald expects his data will reveal distinct patterns, achieve a more sophisticated understanding of marijuana use and predict which subsets of HIV patients are likely to benefit or be harmed by marijuana use.

"We're trying to get a big-picture view," he said. "Hopefully that will lead to more informed decision making by both patients and providers so that there's more open, informed, data-based discussion.

"That could benefit patients and doctors in generating optimal health care plans and also inform policy at a state level, both here and in other states considering legislation."


'/>"/>

Contact: Julie O'Connor
julie.oconnor@wayne.edu
313-577-8845
Wayne State University - Office of the Vice President for Research
Source:Eurekalert

Related medicine news :

1. Wayne State creating computer-based drug intervention for at-risk post-partum women
2. Wayne State to develop a computer-delivered intervention for alcohol use during pregnancy
3. Wayne State University study of heroin users to examine links between stress, drug use
4. Wayne State University to study effects of risky family environments on childhood asthma
5. Wayne State researcher developing treatments for Parkinsons with aid of $2.15 million NIH grant
6. Wayne State University study aims to improve diabetes management in high-risk youth
7. Wayne State University partners with Toyota on safety research
8. Wayne State University researcher to study spinal muscular atrophy
9. Wayne State University awarded $3 million from NIH to foster science and research careers
10. Wayne State researcher receives NSF award to develop neural implants
11. Wayne State University engineering student receives American Tinnitus Association award
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/22/2017)... ... September 22, 2017 , ... ... fallacy of an obligatory tithe, and the freedom experienced when breaking free from ... of published author, Lysa M. Harrison. , Published by Christian Faith Publishing, Lysa ...
(Date:9/22/2017)... ... 22, 2017 , ... First Choice Emergency Room , ... year anniversary of its Houston-Fallbrook facility. , “We are honored to celebrate ... of First Choice Emergency Room Houston-Fallbrook. “It has been a pleasure serving the ...
(Date:9/22/2017)... CA (PRWEB) , ... September 22, 2017 , ... ... to help you brush more effectively even on the go. Their electric toothbrushes ... gingivitis and gum inflammation, with UV sanitizing technology. Combining leading edge Enke technology ...
(Date:9/22/2017)... ... September 22, 2017 , ... “Letters From Home”: a moving compilation ... have value to God. “Letters From Home” is the creation of published author, John ... President’s Cabinet of Jerry Savelle Ministries International, who has traveled and ministered on four ...
(Date:9/22/2017)... ... September 22, 2017 , ... Egg freezing and embryo freezing ... have a slight statistical advantage for live births, frozen eggs offer many advantages, ... women undergoing medical treatment or who are concerned about the decline of their ...
Breaking Medicine News(10 mins):
(Date:9/7/2017)... 2017 Caris Life Sciences, a leading ... promise of precision medicine, today announced results from ... its molecular profiling approach in guiding therapeutic strategies ... plus (CGP+) with Caris Molecular Intelligence ® ... molecular level, leading to more therapeutic options and ...
(Date:9/7/2017)... BOTHELL, Wash. , Sept. 7, 2017   BioLife ... developer, manufacturer and marketer of proprietary clinical grade cell and ... media ("BioLife"), announces that Mike Rice , President and ... Rodman & Renshaw 19 th ... 3:25 p.m. Eastern time (12:25 p.m. Pacific time). The conference ...
(Date:9/6/2017)... 2017   PDI , a leader in infection ... an educational session focused on the role of chlorhexidine ... at the 2017 Annual Scientific Meeting of the Association ... at the Phoenix Convention Center ... 16-19, will also feature PDI,s Prevantics® Device Swab ...
Breaking Medicine Technology: