Navigation Links
Wayne State receives grant to examine exercise's effects on proteins in muscles
Date:9/26/2013

DETROIT Exercise is known to greatly improve the ability of tissues to respond to insulin and reduce the risk for developing type 2 diabetes, but the mechanisms that cause those health benefits are not yet clear.

A Wayne State University researcher is seeking answers by studying the effects of exercise on a process that plays a critical role in insulin signaling within skeletal muscle.

Zhengping Yi, Ph.D., associate professor of pharmaceutical sciences in the Eugene Applebaum College of Pharmacy/Health Sciences and director of the Proteomics Research Laboratory, recently received a three-year grant from the American Diabetes Association for a project titled "Effect of Exercise on Human Skeletal Muscle Tyrosine Phosphoproteome." The award is $180,000 for the first year and up to $200,000 per year for the next two years.

Muscles require energy to help people move, and sugar taken up from circulating blood is a very important source of that energy. After a meal, blood sugar increases, and the pancreas secretes insulin, which triggers cells mainly those of skeletal muscle to absorb the sugar. In obese adults, muscle cells commonly do not respond well to insulin, resulting in a condition called skeletal muscle insulin resistance, a main cause of type 2 diabetes.

Yi's project focuses on the possibility that exercise induces specific yet undiscovered cellular events within skeletal muscle that can allow insulin to work more effectively to help take up blood sugar. Specifically, he is exploring how exercise affects the process of adding and/or removing a phosphate-group (i.e., phosphorus and four oxygen molecules) to or from different proteins at specific locations on those proteins.

Such "phosphorylation" or "de-phosphorylation" events provide important signals for many important cellular processes, including muscle cell uptake of sugar in response to insulin. For example, several reduced protein tyrosine phosphorylatio
'/>"/>

Contact: Julie O'Connor
julie.oconnor@wayne.edu
313-577-8845
Wayne State University - Office of the Vice President for Research
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Wayne State receives $1.57 million grant to develop enhanced radiation therapy training
2. Two AMTC Auditions Are Set for Indianapolis and Fort Wayne on Saturday, September 21, and Monday, September 23
3. New surgical tool may help sleep apnea sufferers, Wayne State research finds
4. Wayne, NJ Teeth Whitening is Performed Using the Zoom Professional Whitening System with Dr. Laurence C. Breiterman of Advanced Dental Technique
5. ENTA Adds a New and Valuable Resource to Its Presence in Passaic County; Welcomes Otolaryngologist Vito Brunetti, M.D. to Its Wayne, NJ Location
6. NIH grant makes STaRs of 8 Wayne State nursing students
7. Race apparently a factor in sleep apnea, Wayne State University researcher finds
8. Wayne State awards $1.8 million to enhance multidisciplinary research
9. The Heart Link Network known as the Best Networking Meetings for Women Opens New Location in Waynesboro, PA
10. Lupus Support Group in Fort Wayne, IN on June 27th
11. Seva Call Launches in Flood Hit Fort Wayne, Indiana
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/16/2014)... Sept. 16, 2014 (HealthDay News) -- Modern forensic techniques ... injuries might have killed King Richard III, the last ... analysis of the king,s skeletal remains, using whole-body CT ... detailed account of the 11 injuries he suffered at ... Aug. 22, 1485. The modern forensics revealed that ...
(Date:9/16/2014)... Not all recovery plans are alike, and ... sure all their patients are receiving the treatment that ... the newly-introduced online therapy. Millennium Treatment Group recently launched ... opportunity to seek treatment from home. , With online ... care at a distance. They provide patients with all ...
(Date:9/16/2014)... 16, 2014 Duke’s Chowder House Lake ... Rebls and Gratafy for a fun evening of ... is firmly cemented. With the growth of companies in these sectors, ... people who work in tech and at startups to connect with ... are happy to host events for their peers to meet and ...
(Date:9/16/2014)... 14, 2014 A new clinical trial ... and drug-eluting balloons (DEB) in treating in-stent ... EES provided superior late angiographic results and ... were reported today at the 26th annual ... by the Cardiovascular Research Foundation (CRF), TCT ...
(Date:9/16/2014)... Programs and policies that promote health and ... dollars in savings for the US health system, according ... help spur these types of improvements, the National Quality ... from across the country to field test the NQF ... handbook designed to assist groups working together to improve ...
Breaking Medicine News(10 mins):Health News:Modern Forensics Provides Clues to Death of Richard III 2Health News:Millennium Treatment Group Now Offers Online Therapy 2Health News:Seattle Seafood Restaurant Duke’s Chowder House Partners with Rebls & Gratafy for Tech Networking Happy Hour Event. 2Health News:Seattle Seafood Restaurant Duke’s Chowder House Partners with Rebls & Gratafy for Tech Networking Happy Hour Event. 3Health News:Results of RIBS IV trial reported at TCT 2014 2Health News:NQF Seeks Field Testing Groups for Population Health Guide 2Health News:NQF Seeks Field Testing Groups for Population Health Guide 3
... the past two decades, medication errors have dramatically increased. DecisionHealth, ... potentially harmful medication errors. , ... Gaithersburg, MD (PRWEB) ... Health Ledger,s recent drug overdose, increased dramatically over the past two ...
... Ind., Aug. 14 Jay C stores are asking,customers ... purchased with,"sell by" dates of July 2 through August ... by Nebraska Beef. Customers should return the ground beef,to ... The recall involves 29 stores Jay C operates in ...
... the Treeman, and the American Doctor Racing to Cure Him on Sunday, ... ... SPRING, Md., Aug. 14 The bizarre growths,covering his body have made Indonesia,s ... Discovery,Health will go beyond the headlines and the tabloids to present the,dramatic true ...
... & enforceable union,election ground rules, ORANGE, Calif., Aug. ... United Healthcare Workers - West:, Caregivers who work ... open letter to the Sisters of St. Joseph of ... the unlawful threats and,intimidation of workers who support forming ...
... Aug. 13 As reported in publications and news,outlets ... "buck" teeth was replaced at the summer games opening ... the decision spawned,disbelief around the globe, sadly, the phenomenon ... of their teeth is nothing new., In a ...
... Corporation, a leading,international manufacturer, marketer, and supplier of ... its financial,results for the second quarter of 2008., ... quarter were $275.2 million, an,increase of 13.9% over ... quarter of,2007. Excluding the impact of favorable foreign ...
Cached Medicine News:Health News:Fatalities From Medication Errors at Home Up Dramatically - DecisionHealth Offers Solutions 2Health News:Fatalities From Medication Errors at Home Up Dramatically - DecisionHealth Offers Solutions 3Health News:Discovery Health Offers the Definitive Look at Indonesia's 'Treeman' in TREEMAN: SEARCH FOR THE CURE 2Health News:Discovery Health Offers the Definitive Look at Indonesia's 'Treeman' in TREEMAN: SEARCH FOR THE CURE 3Health News:As Charges Mount, Caregivers and Supporters Call on Sisters of St. Joseph of Orange to Help Stop Unlawful Intimidation of Workers 2Health News:Summer Games 'Swap' Raises Questions About Image, Oral Health 2Health News:Pregis Announces Second Quarter 2008 Financial Results 2Health News:Pregis Announces Second Quarter 2008 Financial Results 3Health News:Pregis Announces Second Quarter 2008 Financial Results 4Health News:Pregis Announces Second Quarter 2008 Financial Results 5Health News:Pregis Announces Second Quarter 2008 Financial Results 6Health News:Pregis Announces Second Quarter 2008 Financial Results 7Health News:Pregis Announces Second Quarter 2008 Financial Results 8Health News:Pregis Announces Second Quarter 2008 Financial Results 9Health News:Pregis Announces Second Quarter 2008 Financial Results 10Health News:Pregis Announces Second Quarter 2008 Financial Results 11Health News:Pregis Announces Second Quarter 2008 Financial Results 12
(Date:9/16/2014)... Sept. 16, 2014 Research and Markets ... Market 2014-2018" report to their offering. ... of animals. Animal vaccines are generally prepared from weakened or ... their healthy state. Some of the animal vaccines are also ... protein subunits or toxic components. These components ...
(Date:9/16/2014)... 2014  Advanced Medical Isotope Corporation ("AMIC") ... engaged primarily in the development of brachytherapy ... therapeutic applications, today announced that a patent ... brachytherapy products.  AMIC,s rights for the newly ... Battelle, under which AMIC exclusively licensed technologies ...
(Date:9/16/2014)... TUCSON, Ariz. , Sept. 16, 2014 ... describe in a case report the first ... (TAH-t) in a 13- year-old boy with failing Fontan ... When he was 3 years old, the patient ... condition known as functional single ventricle. "The Fontan operation ...
Breaking Medicine Technology:Global Animal Vaccines Market 2014-2018: Key Vendors are Bayer, Elanco, Merck, Novartis, Sanofi and Zoetis 2Global Animal Vaccines Market 2014-2018: Key Vendors are Bayer, Elanco, Merck, Novartis, Sanofi and Zoetis 3Advanced Medical Isotope Corporation Licensed Brachytherapy Seed Patent Granted 2Advanced Medical Isotope Corporation Licensed Brachytherapy Seed Patent Granted 3Advanced Medical Isotope Corporation Licensed Brachytherapy Seed Patent Granted 413-Year-Old Boy with Failed Fontan Circulation Bridged to Transplant Using the SynCardia Total Artificial Heart, Published in Annals of Thoracic Surgery 213-Year-Old Boy with Failed Fontan Circulation Bridged to Transplant Using the SynCardia Total Artificial Heart, Published in Annals of Thoracic Surgery 3
... breakthrough in mental health has been developed, a cooperative ... Foundation; a preventative care program called "Safe ,til Stable." ... time of need through our live 24-hour emergency response ... the trauma experienced by individuals impacted with bipolar disorder. ...
... A Chicago woman will be among the first in the country to, ... get rid of Gastrointestinal Esophageal Reflux Disease (GERD), ... transorally, through the mouth. ... the body, the doctor uses a device to, ...
Cached Medicine Technology:Break-through Preventative Care Program for People Living With Bipolar Disorder 2New Incision-Less Procedure for REFLUX - Experts Consider it to Be Gold Standard for REFLUX 2
... Ruschelit® PVC. 2 eyes, oral. ... patient age. X-ray opaque line. Graduated. ... Designed to reduce kinking of the ... Ruschelit® PVC adapts to the anatomical ...
... Set® Tube with stylet inside. Sterile, ... uncuffed Rusch endotracheal tube with a ... use saving you time and storage ... for easy identification and has a ...
... Clear Plus™ Cuffed Endotracheal Tube w. Flexi -Slip™ ... Single use. A quality Rusch endotracheal tube with ... saving you time and storage space. The stylet ... withdrawal. It is designed with a soft distal ...
Ruschelit® PVC. Siliconized. Stainless steel spiral reinforced. High volume/low pressure cuff. Permanent connector. X-ray opaque. Single use. Sterile...
Medicine Products: