Navigation Links
Wayne State University to study novel treatment for antibiotic-resistant bacteria
Date:11/16/2011

DETROIT The bacteria Enterococcus can cause infections that typically target the digestive tract or bowel; if the bacteria spread, an abdominal abscess or urinary infection could result. Enterococcus also can invade the bloodstream, leading to meningitis, pneumonia or endocarditis an infection of the heart valve. Typically the only people who become ill from this bacteria are the elderly and those who already have health issues, such as diabetes or chronic kidney failure. Enterococcus infections can be serious in these populations.

The bacteria are resistant to a number of antibiotics, but in the past, physicians were able to effectively treat Enterococcus infections with the drug vancomycin. However, during recent years, Enterococcus has become resistant to vancomycin treatment, and the new strain, known as vancomycin-resistant Enterococcus (VRE), is resistant to other antibiotics as well. It also is able to transfer its treatment-resistance abilities to unrelated bacteria such as MRSA or methicillin-resistant Staphylococcus aureus.

Researchers at Wayne State University recently received funding from the National Institute of Allergy and Infectious Diseases of the National Institutes of Health to study a novel antibiotic that may treat VRE infection and decrease mortality. This nearly $430,000 grant led by Michael J. Rybak, Pharm.D., M.P.H., professor of pharmacy practice and director of the Anti-Infective Research Laboratory in WSU's Eugene Applebaum College of Pharmacy and Health Sciences, will provide a better understanding and treatment of this infectious disease.

According to Rybak, daptomycin, a novel lipopeptide antibiotic, shows great promise as a new therapy for VRE infections. "This research study aims to define the dose exposure breakpoint required for daptomycin to ultimately optimize patient response to treatment and prevent the emergence of resistance," he said.

Once Rybak and his team determine the optimal doses of daptomycin, the result will be greater bactericidal activity, prevention of resistance and preservation of daptomycin as a viable antibiotic for continued clinical use.


'/>"/>

Contact: Julie O'Connor
julie.oconnor@gmail.com
313-577-8845
Wayne State University - Office of the Vice President for Research
Source:Eurekalert

Related medicine news :

1. Wayne State therapeutic marijuana use study could impact state policies, guide treatment
2. Wayne State creating computer-based drug intervention for at-risk post-partum women
3. Wayne State to develop a computer-delivered intervention for alcohol use during pregnancy
4. Wayne State University study of heroin users to examine links between stress, drug use
5. Wayne State University to study effects of risky family environments on childhood asthma
6. Wayne State researcher developing treatments for Parkinsons with aid of $2.15 million NIH grant
7. Wayne State University study aims to improve diabetes management in high-risk youth
8. Wayne State University partners with Toyota on safety research
9. Wayne State University researcher to study spinal muscular atrophy
10. Wayne State University awarded $3 million from NIH to foster science and research careers
11. Wayne State researcher receives NSF award to develop neural implants
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/27/2016)... ... ... "FCPX editors can now reveal their media with growing colorful split screen ... - CEO of Pixel Film Studios. , ProSlice Color brings the split screens ... reveal the media of their split screens with growing colorful panels. , ProSlice Color ...
(Date:6/27/2016)... ... June 27, 2016 , ... TopConsumerReviews.com recently awarded their highest five-star rating to ... of individuals in the United States and Canada wear eyeglasses. Once considered to be ... vision and make a fashion statement. Even celebrities use glasses as a way of ...
(Date:6/26/2016)... ... June 26, 2016 , ... PawPaws brand pet supplements owned ... developed to enhance the health of felines. The formula is all-natural and is made ... in the PawPaws Cat Kidney Support Supplement Soft Chews are Astragalus Root ...
(Date:6/25/2016)... ... June 25, 2016 , ... Austin residents seeking Mohs surgery services, ... Mohs Surgery and to Dr. Russell Peckham for medical and surgical dermatology. , Dr. ... skin cancer. The selective fellowship in Mohs Micrographic Surgery completed by Dr. Dorsey was ...
(Date:6/25/2016)... CA (PRWEB) , ... June 25, 2016 , ... As ... with Magna Cum Laude and his M.D from the David Geffen School of Medicine ... and returned to Los Angeles to complete his fellowship in hematology/oncology at the UCLA-Olive ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... 23, 2016 Revolutionary technology includes ... Oticon , industry leaders in advanced audiology and hearing ... Oticon Opn ™, the world,s first internet connected hearing ... IoT devices.      (Photo: http://photos.prnewswire.com/prnh/20160622/382240 ... number of ,world firsts,: , TwinLink™ - ...
(Date:6/23/2016)... Research and Markets has announced ... Analysis (United States, China, Japan, Brazil, United Kingdom, Germany, ... offering. Surgical Procedure ... planners, provides surgical procedure volume data in a geographic ... in-depth analysis of growth drivers and inhibitors, including world ...
(Date:6/23/2016)... , June 23, 2016  The National ... has joined the health policy research organization as ... Romano , MD, senior vice president and chief ... company,s representative on the NPC Board of Directors. ... pleased that Mallinckrodt has joined us in support ...
Breaking Medicine Technology: