Navigation Links
Wayne State University to study novel treatment for antibiotic-resistant bacteria
Date:11/16/2011

DETROIT The bacteria Enterococcus can cause infections that typically target the digestive tract or bowel; if the bacteria spread, an abdominal abscess or urinary infection could result. Enterococcus also can invade the bloodstream, leading to meningitis, pneumonia or endocarditis an infection of the heart valve. Typically the only people who become ill from this bacteria are the elderly and those who already have health issues, such as diabetes or chronic kidney failure. Enterococcus infections can be serious in these populations.

The bacteria are resistant to a number of antibiotics, but in the past, physicians were able to effectively treat Enterococcus infections with the drug vancomycin. However, during recent years, Enterococcus has become resistant to vancomycin treatment, and the new strain, known as vancomycin-resistant Enterococcus (VRE), is resistant to other antibiotics as well. It also is able to transfer its treatment-resistance abilities to unrelated bacteria such as MRSA or methicillin-resistant Staphylococcus aureus.

Researchers at Wayne State University recently received funding from the National Institute of Allergy and Infectious Diseases of the National Institutes of Health to study a novel antibiotic that may treat VRE infection and decrease mortality. This nearly $430,000 grant led by Michael J. Rybak, Pharm.D., M.P.H., professor of pharmacy practice and director of the Anti-Infective Research Laboratory in WSU's Eugene Applebaum College of Pharmacy and Health Sciences, will provide a better understanding and treatment of this infectious disease.

According to Rybak, daptomycin, a novel lipopeptide antibiotic, shows great promise as a new therapy for VRE infections. "This research study aims to define the dose exposure breakpoint required for daptomycin to ultimately optimize patient response to treatment and prevent the emergence of resistance," he said.

Once Rybak and his team determine the optimal doses of daptomycin, the result will be greater bactericidal activity, prevention of resistance and preservation of daptomycin as a viable antibiotic for continued clinical use.


'/>"/>

Contact: Julie O'Connor
julie.oconnor@gmail.com
313-577-8845
Wayne State University - Office of the Vice President for Research
Source:Eurekalert

Related medicine news :

1. Wayne State therapeutic marijuana use study could impact state policies, guide treatment
2. Wayne State creating computer-based drug intervention for at-risk post-partum women
3. Wayne State to develop a computer-delivered intervention for alcohol use during pregnancy
4. Wayne State University study of heroin users to examine links between stress, drug use
5. Wayne State University to study effects of risky family environments on childhood asthma
6. Wayne State researcher developing treatments for Parkinsons with aid of $2.15 million NIH grant
7. Wayne State University study aims to improve diabetes management in high-risk youth
8. Wayne State University partners with Toyota on safety research
9. Wayne State University researcher to study spinal muscular atrophy
10. Wayne State University awarded $3 million from NIH to foster science and research careers
11. Wayne State researcher receives NSF award to develop neural implants
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/16/2017)... ... August 16, 2017 , ... ... affiliations and de novo development, today announced Cumberland Skin Surgery and Dermatology ... Surgery and Dermatology, with offices in both Hermitage and Lebanon, Tennessee, provides comprehensive ...
(Date:8/16/2017)... ... 2017 , ... Paul Vitenas, MD, FACS , is honored to announce ... list identifies the nation’s top physicians, in a variety of specialties. This marks the ... of Castle Connolly’s coveted ranking. , Castle Connolly is the nation’s trusted provider of ...
(Date:8/16/2017)... ... August 16, 2017 , ... SGNA Standards of ... every reprocessing cycle, both between patient procedures and before storage, is a requisite ... as important to the prevention of disease transmission and nosocomial infection as cleaning ...
(Date:8/16/2017)... , ... August 16, 2017 , ... ... $5.99, eBook, 9781498499620    ) shares that during the time of a cancer diagnosis, surgery ... of God's love, and all the many ways God shows love to those ...
(Date:8/16/2017)... ... August 16, 2017 , ... ... an opportunity for men and women to train as hospice volunteers. Volunteers provide ... life-limiting illness. For over 30 years, the agency has trained volunteers to be ...
Breaking Medicine News(10 mins):
(Date:8/2/2017)... Aug. 2, 2017  Life Flight Network and PeaceHealth Oregon ... improves patient care and operational efficiency for patients at hospitals ... , Cottage Grove , and ... PeaceHealth and Life Flight Network work collaboratively to move patients ... or when a time sensitive emergency exists. ...
(Date:7/31/2017)... , July 31, 2017 Three Tru-D SmartUVC robots ... South Korea . Tru-D, short for "Total Room Ultraviolet Disinfection," ... rooms after an environmental services (ES) professional cleans the area with traditional ... Tru-D ... "Although the BAACH has ...
(Date:7/27/2017)... Biomet Holdings, Inc. (NYSE and SIX: ZBH) today reported financial ... Company reported second quarter net sales of $1.954 billion, ... and an increase of 2.1% on a constant currency ... the LDR Holding Corporation acquisition, second quarter 2017 revenues ... 0.3% on a constant currency basis. ...
Breaking Medicine Technology: