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Wayne State University researcher to study spinal muscular atrophy
Date:9/9/2011

hat downregulation of SNCA can compromise the viability of neural cells."

In this study, Parker will put SNCA to the test. He aims to determine whether dramatically decreasing SNCA expression levels will mimic the motor neuron death observed under SMA conditions. He will then increase SNCA expression levels to see if this slows the progression of SMA.

Parker expects his findings to come with important implications for the discovery of new therapies. "The knowledge gained from this research is a highly desirable goal, potentially allowing us to identify more useful disease markers for future clinical trials, as well as develop new models to advance neuromuscular disease research," said Parker.


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Contact: Julie O'Connor
julie.oconnor@wayne.edu
313-577-8845
Wayne State University - Office of the Vice President for Research
Source:Eurekalert

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