Navigation Links
Wayne State University Scientists ID New Biomarker for Prostate Cancer
Date:3/26/2009

DETROIT, March 26 /PRNewswire-USNewswire/ -- Researchers at Wayne State University have identified a new marker for prostate cancer progression that may one day lead to new treatments.

Prostate cancer, one of the most prevalent non-skin cancers in America, affects one in six men. In 2008, nearly two million Americans were being treated for prostate cancer; nearly 186,000 were newly diagnosed, and approximately 28,000 died from the disease.

Avraham Raz, professor of pathology and radiation oncology in the School of Medicine at Wayne State University and the Karmanos Cancer Institute, and his team of renowned research collaborators identified a cleaved form of galectin-3 as a marker for prostate cancer progression. According to the study published in the April 2009 issue of The American Journal of Pathology, previous research indicated that decreased levels of galectin-3 are linked with neoplastic progression in prostate cancer. However, increased levels of galectin-3 are believed to be associated with tumorigenicity in other tumor types.

The study found that cleaved galectin-3, an inheritable gene, is present in late-stage prostate cancer, and that by reducing levels of galectin-3, development of metastatic prostate cancer is inhibited. This finding suggests that galectin-3 may serve as both a diagnostic marker and therapeutic target for future prostate cancer treatments.

"Dr. Raz's brilliant research is leading us closer to discovering the genetic risk factors for developing not only prostate cancer, but other cancers as well," said Dr. Gloria Heppner, associate vice president for research at Wayne State. "His work at Wayne State and the Karmanos Cancer Institute is another example of the tremendous research we are doing to uncover the cause of this prevalent disease, which ultimately will lead to new treatments that will save lives."

Other School of Medicine researchers involved in this study include Drs. Yi Wang, Pratima Nangia-Makker, Vitaly Balan, Victor Hogan and Larry Tait. Dr. Kenneth J. Pienta of the departments of internal medicine and urology at the University of Michigan also collaborated in this study.

Wayne State University is one of the nation's pre-eminent public research universities in an urban setting, ranking in the top 50 in R & D expenditures of all public universities by the National Science Foundation. Through its multidisciplinary approach to research and education, and its ongoing collaboration with government, industry and other institutions, the university seeks to enhance economic growth and improve the quality of life in the city of Detroit, state of Michigan and throughout the world. WSU's School of Medicine is the nation's largest single-campus medical school. Together with the Wayne State University Physician Group and 13 hospital partners, the school is a leader in medical education, biomedical research, and patient care. Its programs of excellence include cancer, maternal-child health, neurosciences, and population studies and urban health.


'/>"/>
SOURCE Wayne State University
Copyright©2009 PR Newswire.
All rights reserved

Related medicine news :

1. Response Biomedical appoints S. Wayne Kay Chief Executive Officer
2. Blue Cross Blue Shield of Michigan Awards Grant to Reduce Accidental Infant Suffocations in Wayne County
3. Enova Medical Technologies Names Wayne Ramaker Vice President of Marketing and Communications
4. EPA Recognizes Fort Wayne Community Schools for Reducing Diesel Emissions From Its School Buses
5. 2008 Caregiving Conferences Come to Wayne County, Offering Free Workshops and Resources in Canton and Taylor Locations
6. First Study of War-Related Mental Disorders Among Iraqis 10 Years Post-Gulf War Published by Researchers at Wayne State University and Basrah University, Iraq
7. Wayne County Medical Society Foundation To Host Holiday Party For Underprivileged Children Saturday
8. New Zealand Waynes New Resources Development Co., Ltd. Completes Reverse Merger to Go Public in the U.S.
9. Andre Konski, M.D., M.B.A., Accepts Radiation Oncology Position at Wayne State University and the Karmanos Cancer Institute
10. Elder Abuse Prevention the Focus of Wayne County Medical Society Foundations Annual Chinese New Year Fundraiser
11. Wayne County Community College District Presents Second Annual Child Car Seat Check Program
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... , ... October 13, 2017 , ... Apple Rehab ... services, staged a mock evacuation of the facility as part of a disaster drill ... Department, Echo Hose EMS and Shelton City Emergency Manager, as well as the ...
(Date:10/13/2017)... ... October 13, 2017 , ... Ellevate Network, the leading network for professional women, ... towards gender equality at their inaugural Summit in New York City in June. The ... social audience of over 3 million. To watch the Mobilize Women video, click ...
(Date:10/13/2017)... ... , ... Talented host, actor Rob Lowe, is introducing a ... episode of "Success Files," which is an award-winning educational program broadcasted on PBS ... in-depth with passion and integrity. , Sciatica occurs when the sciatic nerve in ...
(Date:10/13/2017)... ... 13, 2017 , ... “America On The Brink”: the Christian history of the ... is the creation of published author, William Nowers. Captain Nowers and his wife, ... he spent thirty years in the Navy. Following his career as a naval ...
(Date:10/12/2017)... ... October 12, 2017 , ... Planet Fitness, one of ... announced today its plans to open a flagship location in Covington, LA at 401 ... Rooms To Go store next to Office Depot in the Holiday Square shopping center. ...
Breaking Medicine News(10 mins):
(Date:9/27/2017)... Israel and NEW YORK , Sept. 27, ... with mobile health and big data solutions, today announced that its MyDario ... Please check your local TV listings for when The Dr. Oz Show ... ... season this month. ...
(Date:9/25/2017)... 25, 2017  EpiVax, Inc., a leader in ... immune-engineering today announced the launch of EpiVax Oncology ... personalized therapeutic cancer vaccines. EpiVax has provided $500,000 ... to enabling technologies to the new precision immunotherapy ... EpiVax Oncology as Chief Executive Officer. Gad brings ...
(Date:9/22/2017)... ROCKVILLE, Md. , Sept. 22, 2017  As ... by Republican Senators Bill Cassidy (R-LA) and ... Kalorama Information notes that the medical device industry is ... the medical device tax, the 2.3% excise tax on ... Act.  But they also want covered patients, increased visits ...
Breaking Medicine Technology: