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Waters Corporation Announces the Purchase of UPLC/MS Systems by the National Cancer Institute for Advanced Metabolomics Research
Date:4/1/2009

ACQUITY UltraPerformance Liquid Chromatography Paired With Xevo TQ and Synapt HDMS Mass Spectrometers Target Small Molecule Biomarkers Linked to Disease

MILFORD, Mass., April 1 /PRNewswire-FirstCall/ -- Waters Corporation (NYSE: WAT) announced today that the National Cancer Institute's Center for Cancer Research in Bethesda, Md., purchased Waters(R) ACQUITY UPLC(R)/Synapt High Definition MS (HDMS(TM)) and Waters ACQUITY(R) UPLC/Xevo(TM) TQ MS Systems for its metabolomics research programs. The research is aimed at discovering small molecule metabolites, or biomarkers, associated with cancer susceptibility and diagnosis, treatment efficacy and the adverse effects of medicines and other chemicals. Researchers are confident these tools will lead to a better understanding of the mechanisms of the disease and its diagnosis, treatment and prevention.

Identifying and quantifying the thousands of metabolic biomarkers present in a complex sample such as urine can be a daunting task. Only with the most sensitive of instruments and most powerful of software can researchers uncover and pinpoint the important biomarkers that may be present even in the smallest of quantities. This level of advanced research requires analytical tools with exceptional separations and confirmatory power, and the speed and reliability to analyze thousands of samples per month. Since purchasing an ACQUITY UPLC/Q-Tof Premier(TM) mass spectrometer in 2005, the Center has tested 80,000 samples using this system in support of various research studies.

Waters ACQUITY UPLC System employs 1.7 micron particles in analytical columns that permit higher chromatographic resolution, shorter analysis times, and the use of less solvent per sample. Paired with tandem quadrupole and quadrupole time-of-flight/ion mobility mass spectrometry, the sharper chromatographi
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SOURCE Waters Corporation
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