Navigation Links
Warning signs predict kidney injury after surgery
Date:8/11/2011

Washington, DC (August 12, 2011) Acute kidney injury (AKI) is a common but preventable -- complication after surgery that can lead to other complications or even death. The use and development of biomarkers will help physicians diagnose and treat acute kidney injury. Three protein measurements indicate who has a high risk of developing kidney injury after heart surgery, according to two studies appearing in an upcoming issue of the Journal of the American Society of Nephrology.

"To date, these are the largest studies in adults and children comparing and validating the performance of three of the most frequently studied markers of kidney injury," said author Chirag Parikh, MD, PhD (Yale University School of Medicine).

The studies included more than 1,200 adults and 300 children undergoing heart surgery throughout North America. Frequent urine and blood samples were collected to measure levels of three proteins -- urine interleukin-18 (IL-18) and urine and plasma (blood) neutrophil gelatinase-associated lipocalin (NGAL)and assess their ability to predict who will develop kidney injury after surgery.

Traditionally, kidney trouble is assessed by measuring the blood protein creatinine, which is not ideal because it has a delayed resultit does not pick up early damage and injury to the kidneys.

"We demonstrated that the three proteins in our study identify kidney injury soon after surgery and 24 to 48 hours earlier than creatinine, and shows a similar result," according to Parikh.

Risk of kidney injury was especially highmore than six times higherfor adults and children with the highest levels of urine IL-18. Plasma NGAL also predicted kidney injury in adults, whereas urine NGAL was not an accurate predictor in adults once results were adjusted for other factors. Urine IL-18 and urine, but not plasma, NGAL were accurate predictors in children.

Doctors may wish to measure these urine or blood proteins
'/>"/>

Contact: Adrienne Lea
alea@asn-online.org
202-503-6560
American Society of Nephrology
Source:Eurekalert

Page: 1 2

Related medicine news :

1. American Heart Association Rapid Access Journal Report: Study Finds Racial Gaps Continue in Heart Disease Awareness, Low Knowledge of Heart Attack Warning Signs Among Women
2. Connecticut Board Considers Warning About Risk Of Stroke Following Chiropractic Neck Manipulation
3. FDA Issues Warning on Key Asthma Drugs
4. Warning: Immigrating to North America may foster smoking in children
5. UNC study: Obese 3-year-olds show early warning signs for future heart disease
6. A Warning to Negligent Apartment Building Landlords in New York From Personal Injury Lawyer, David Perecman
7. Americans for Responsible Health Care Launch Radio Ads Targeting Seven Democrats, Warning The People Are Watching...
8. Not All Slings Are Created Equally: Baby Sling & Carrier Manufacturers Speak Out On Baby Sling Safety Warning
9. FDA Issues Warning on Fat-Melting Spa Injections
10. Warning Over Dangers of Used Racking Issued By Thistle Systems
11. Normal Blood Pressure in Male Teens a Warning Sign
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/27/2015)... May 27, 2015 Ticket Down is a reputable ... The Chicago Blackhawks are currently in the middle of their series ... in the series. If the Blackhawks can win tonight at ... played on Saturday, May 30th at the Honda Center in Anaheim. ... best record in the Western Conference as they won the Pacific ...
(Date:5/27/2015)... 27, 2015 As the U.S. Supreme ... health insurance under the Affordable Care Act (ACA), an ... Public Health, the RAND Corporation and Express Scripts provides ... a million initial enrollees. , The analysis is ... Affairs and will also appear in the journal’s June ...
(Date:5/27/2015)... CA (PRWEB) May 27, 2015 Khanna Vision ... the art web portal focussed on keratoconus eye disease ... relentless progressive disease has its onset in the teenage years. ... The cornea or the front clear part of the eye ... pressure in the eye. It results in poor vision which ...
(Date:5/27/2015)... 27, 2015 “We are honored to ... executive vice president and vice president of clinical affairs ... possible allows us to provide comprehensive care to more ... , SSCHC provides clinical care and behavioral health services ... in 2014, many of whom took advantage of the ...
(Date:5/27/2015)... (PRWEB) May 27, 2015 Hundreds ... on behalf of individuals who allegedly suffered gynecomastia ... the use of the antipsychotic drug continue to ... underway in Pennsylvania’s Philadelphia Court of Common Pleas. ... with its bellwether trial program, as the third ...
Breaking Medicine News(10 mins):Health News:Blackhawks vs. Ducks NHL Western Conference Finals Tickets: Ticket Down Slashes Ticket Prices on Chicago Blackhawks vs. Anaheim Ducks 2015 NHL Western Conference Finals 2Health News:Large-Scale Analysis of Medication Data Provides Insights into Who Is Covered by Affordable Care Act 2Health News:Large-Scale Analysis of Medication Data Provides Insights into Who Is Covered by Affordable Care Act 3Health News:Large-Scale Analysis of Medication Data Provides Insights into Who Is Covered by Affordable Care Act 4Health News:KVI announced the launch of The Keratoconus website focused on age based keratoconus treatment . 2Health News:Sixteenth Street Community Health Centers To Expand Primary Care and Behavioral Health Services Through $1 Million Grant From Aurora's Better Together Fund 2Health News:Risperdal Lawsuit Attorneys at Bernstein Liebhard LLP Look Forward to Start of Third Gynecomastia Bellwether Trial in Pennsylvania 2Health News:Risperdal Lawsuit Attorneys at Bernstein Liebhard LLP Look Forward to Start of Third Gynecomastia Bellwether Trial in Pennsylvania 3
... MMR(measles, mumps and rubella) vaccine and bowel disorders and autism has ... the assurances extended by government experts and all the ... by the Department of Health, and tests are to be ... by the vaccine. The offer comes after a new study found ...
... spells heaven for millions of avian influenza patients there is ... //. According to them they have developed in the lab ... the avian influenza virus H5N1. The scientific discovery is that ... future variants/mutants of the virus. ,The great ...
... people across the globe die every year of ... revealed Friday//. ,The four main diseases influenced ... tract infection, various forms of unintentional injuries and ... "Preventing Disease through Healthy Environments", underlined that over ...
... guess on what could be top of the heap among ... open as a common affliction// , needs urgent remedy, because ... become a social problem. ,It is estimated that ... this debilitating ailment that renders them unemployed. Sadly, most of ...
... patients in Bihar, a high profile meeting of members ... those connected// with AIDS awareness programme has been called ... drive against the dreaded disease, official sources said today. ... brainstorming session on June 24 here, the sources said. ...
... The Royal Free Hospital in Northwest London where Peter Butler ... await the approval// from the ethics board for going ahead ... the ethics board had given Butler and his team permission ... patients regarding the risks involved, now it is in the ...
Cached Medicine News:Health News:Striking a Gold Mine: H5N1 Vaccine may Serve as an Antidote for Mutants and Variants 2Health News:13 million environment-linked deaths every year: WHO 2
(Date:5/27/2015)... DUBLIN , May 27, 2015 /PRNewswire/ ... ) has announced the addition of the  ... Trends And Forecasts (2014 - 2019)" ...      (Logo: http://photos.prnewswire.com/prnh/20130307/600769) , , ,Ultrasound is ... sound waves to look at body parts ...
(Date:5/27/2015)... , May 27, 2015  LumiThera Inc., a ... photobiomodulation (PBM) treatment for ocular disorders and disease, ... Washington State Life Sciences Discovery Fund ... recipients of the LSDF matching grants worth $500,000 ... for subjects with dry age-related macular degeneration (AMD). ...
(Date:5/27/2015)... -- Research and Markets( http://www.researchandmarkets.com/research/hxhwtv/asia_pacific ) has announced the ... Growth, Trends And Forecasts (2014 - 2019)" company ... Asia Pacific market for Fluoroscopy is expected ... 2020 Fluoroscopy is the imaging technology which ... interior of the body. The imaging team consists of ...
Breaking Medicine Technology:Asia Pacific Ultrasound Devices Market Report 2015 - Growth, Trends And Forecasts 2014 - 2019 2LumiThera Receives LSDF Commercialization Grant Award 2Asia Pacific Fluoroscopy Market Trends and Forecasts 2014 - 2019 2
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: