Navigation Links
Warning signs predict kidney injury after surgery
Date:8/11/2011

Washington, DC (August 12, 2011) Acute kidney injury (AKI) is a common but preventable -- complication after surgery that can lead to other complications or even death. The use and development of biomarkers will help physicians diagnose and treat acute kidney injury. Three protein measurements indicate who has a high risk of developing kidney injury after heart surgery, according to two studies appearing in an upcoming issue of the Journal of the American Society of Nephrology.

"To date, these are the largest studies in adults and children comparing and validating the performance of three of the most frequently studied markers of kidney injury," said author Chirag Parikh, MD, PhD (Yale University School of Medicine).

The studies included more than 1,200 adults and 300 children undergoing heart surgery throughout North America. Frequent urine and blood samples were collected to measure levels of three proteins -- urine interleukin-18 (IL-18) and urine and plasma (blood) neutrophil gelatinase-associated lipocalin (NGAL)and assess their ability to predict who will develop kidney injury after surgery.

Traditionally, kidney trouble is assessed by measuring the blood protein creatinine, which is not ideal because it has a delayed resultit does not pick up early damage and injury to the kidneys.

"We demonstrated that the three proteins in our study identify kidney injury soon after surgery and 24 to 48 hours earlier than creatinine, and shows a similar result," according to Parikh.

Risk of kidney injury was especially highmore than six times higherfor adults and children with the highest levels of urine IL-18. Plasma NGAL also predicted kidney injury in adults, whereas urine NGAL was not an accurate predictor in adults once results were adjusted for other factors. Urine IL-18 and urine, but not plasma, NGAL were accurate predictors in children.

Doctors may wish to measure these urine or blood proteins
'/>"/>

Contact: Adrienne Lea
alea@asn-online.org
202-503-6560
American Society of Nephrology
Source:Eurekalert

Page: 1 2

Related medicine news :

1. American Heart Association Rapid Access Journal Report: Study Finds Racial Gaps Continue in Heart Disease Awareness, Low Knowledge of Heart Attack Warning Signs Among Women
2. Connecticut Board Considers Warning About Risk Of Stroke Following Chiropractic Neck Manipulation
3. FDA Issues Warning on Key Asthma Drugs
4. Warning: Immigrating to North America may foster smoking in children
5. UNC study: Obese 3-year-olds show early warning signs for future heart disease
6. A Warning to Negligent Apartment Building Landlords in New York From Personal Injury Lawyer, David Perecman
7. Americans for Responsible Health Care Launch Radio Ads Targeting Seven Democrats, Warning The People Are Watching...
8. Not All Slings Are Created Equally: Baby Sling & Carrier Manufacturers Speak Out On Baby Sling Safety Warning
9. FDA Issues Warning on Fat-Melting Spa Injections
10. Warning Over Dangers of Used Racking Issued By Thistle Systems
11. Normal Blood Pressure in Male Teens a Warning Sign
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/20/2014)... Los Angeles, CA (PRWEB) August 20, 2014 ... Conference will get a sneak peak at Los Angeles’ ... along with a tour of a blossoming 1.5-acre high ... visit to a shipping container farm in the L.A. ... the wide-ranging diversity of sustainable urban agriculture, will kick ...
(Date:8/20/2014)... 2014 August is Children’s Eye Health ... educated about eye health and safety for their children ... eye condition that must be checked for, according to ... of Water radio show, is pediatric dry eye. With ... dry eye is becoming a very real concern to ...
(Date:8/20/2014)... OXNARD, CA (PRWEB) August 20, 2014 ... Saj Jivraj, founder of the Anacapa Dental Art Institute, ... month. , Dr. Jivraj will be speaking on ... and Laboratory Aspects of Graft Less Solutions” at 12:40 ... Conference Centre in Vancouver, British Columbia, Canada. , “The ...
(Date:8/20/2014)... Inc. Magazine recently named Etransmedia ... annual Inc. 500|5000, an exclusive ranking of the ... most comprehensive look at the most important segment ... Yelp, Pandora, Timberland, Dell, Domino’s Pizza, LinkedIn, Zillow ... as members of the Inc. 500|5000. , “We ...
(Date:8/20/2014)... “Have you recently been involved in an ... injury lawyer serving the greater Seattle area. “Are you still ... then keep reading . , In a recently released article, ... auto accident can use to see if they may qualify ... injury insurance claim will allow an individual to receive medical ...
Breaking Medicine News(10 mins):Health News:Seedstock Sustainable Agriculture Conference’s Urban Farm Field Trip to Offer First Look at Los Angeles’ Premier Food Business Incubator 2Health News:Seedstock Sustainable Agriculture Conference’s Urban Farm Field Trip to Offer First Look at Los Angeles’ Premier Food Business Incubator 3Health News:August is Children’s Eye Health Month, Exams Must Check for Pediatric Dry Eye 2Health News:August is Children’s Eye Health Month, Exams Must Check for Pediatric Dry Eye 3Health News:Internationally Known Oxnard Dentist to Speak at Conference in Vancouver 2Health News:Internationally Known Oxnard Dentist to Speak at Conference in Vancouver 3Health News:Etransmedia Makes Exclusive List for the Eighth Consecutive Year in Inc. Magazine 2Health News:Etransmedia Makes Exclusive List for the Eighth Consecutive Year in Inc. Magazine 3Health News:Five Questions to Determine Who Qualifies for a Personal Injury Claim Recently Released by The Jones Firm in Recent Article 2
... 5 Chiltern, a leading global research,organization, is proud ... Clinical Researcher of the Year ceremony, including the coveted,Clinical ... following awards: Gold: Clinical Department of the Year ... Project Manager category Gold: Kara Tanabe in Clinical ...
... evidence shows that surgery may effectively cure Type 2 diabetes -- ... is treated, but that introduces a new way of thinking about ... to the February issue of Diabetes Care by a leading expert ... small bowel as the possible site of critical mechanisms for the ...
... 5 A protein that governs,development of human ... spread of malignant melanoma, the deadliest skin cancer, ... the transformation of skin pigment cells or melanocytes, ... and a median survival of less than 7.5 ...
... INDIANAPOLIS, March 5 Anthem National Accounts today,announced ... to address,the needs of early retirees -- a ... of products is designed to meet the needs ... and provide affordable,access to medical coverage while helping ...
... to protect their children from exposure to secondhand smoke, ... Hopkins Bloomberg School of Public Health. Exposure to secondhand ... for numerous illnesses and premature death. The household study, ... parents who smoked reported smoking around their children. Measurements ...
... Kids Pledges up to ... Type 1 Diabetes Research, ATLANTA, March 5 White Hat ... announced today the launch of a,three- year partnership with the Juvenile ... 1,diabetes research., As part of this milestone relationship, White Hat ...
Cached Medicine News:Health News:Chiltern Wins Top Prize 2Health News:Type 2 diabetes may be caused by intestinal dysfunction 2Health News:Type 2 diabetes may be caused by intestinal dysfunction 3Health News:Type 2 diabetes may be caused by intestinal dysfunction 4Health News:Protein in Human Embryonic Stem Cells Controls Malignant Tumor Cells 2Health News:Protein in Human Embryonic Stem Cells Controls Malignant Tumor Cells 3Health News:Protein in Human Embryonic Stem Cells Controls Malignant Tumor Cells 4Health News:Anthem National Accounts Introduces New Products for Large Employers' Early Retirees 2Health News:Anthem National Accounts Introduces New Products for Large Employers' Early Retirees 3Health News:Secondhand smoke a risk for children worldwide 2Health News:White Hat Brands, Juvenile Diabetes Research Foundation Offer the 'Juice' on New Partnership 2Health News:White Hat Brands, Juvenile Diabetes Research Foundation Offer the 'Juice' on New Partnership 3
(Date:8/19/2014)... Research and Markets has announced the addition of ... Report" report to their offering. This ... in US$ Million by the following Brands: Humatrope, Norditropin, Genotropin, ... comprehensive analytics for the US, Canada , ... Asia-Pacific , and Rest of World. Annual ...
(Date:8/19/2014)... 2014 According to Kalorama Information, electronic medical ... Big Data in healthcare a reality, and this a ... the American Recovery and Reinvestment Act, the U.S. government ... and penalties will start applying soon for use of ... complete study of the EMR industry, EMR 2014: ...
(Date:8/19/2014)... 19, 2014 Oramed Pharmaceuticals ... pharmaceutical company focused on the development of oral ... Property Department of Spain ... titled "Methods and Compositions for Oral Administrations of ... Oramed Pharmaceuticals is a technology pioneer in the ...
Breaking Medicine Technology:Global Human Growth Hormone Drugs - Strategic Business Report 2014 2Kalorama: EMR Paves the Way for Big Data 2Kalorama: EMR Paves the Way for Big Data 3Oramed Granted Patent in Spain for Oral Administration of Insulin 2Oramed Granted Patent in Spain for Oral Administration of Insulin 3
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: