Navigation Links
Warning signs predict kidney injury after surgery
Date:8/11/2011

Washington, DC (August 12, 2011) Acute kidney injury (AKI) is a common but preventable -- complication after surgery that can lead to other complications or even death. The use and development of biomarkers will help physicians diagnose and treat acute kidney injury. Three protein measurements indicate who has a high risk of developing kidney injury after heart surgery, according to two studies appearing in an upcoming issue of the Journal of the American Society of Nephrology.

"To date, these are the largest studies in adults and children comparing and validating the performance of three of the most frequently studied markers of kidney injury," said author Chirag Parikh, MD, PhD (Yale University School of Medicine).

The studies included more than 1,200 adults and 300 children undergoing heart surgery throughout North America. Frequent urine and blood samples were collected to measure levels of three proteins -- urine interleukin-18 (IL-18) and urine and plasma (blood) neutrophil gelatinase-associated lipocalin (NGAL)and assess their ability to predict who will develop kidney injury after surgery.

Traditionally, kidney trouble is assessed by measuring the blood protein creatinine, which is not ideal because it has a delayed resultit does not pick up early damage and injury to the kidneys.

"We demonstrated that the three proteins in our study identify kidney injury soon after surgery and 24 to 48 hours earlier than creatinine, and shows a similar result," according to Parikh.

Risk of kidney injury was especially highmore than six times higherfor adults and children with the highest levels of urine IL-18. Plasma NGAL also predicted kidney injury in adults, whereas urine NGAL was not an accurate predictor in adults once results were adjusted for other factors. Urine IL-18 and urine, but not plasma, NGAL were accurate predictors in children.

Doctors may wish to measure these urine or blood proteins
'/>"/>

Contact: Adrienne Lea
alea@asn-online.org
202-503-6560
American Society of Nephrology
Source:Eurekalert

Page: 1 2

Related medicine news :

1. American Heart Association Rapid Access Journal Report: Study Finds Racial Gaps Continue in Heart Disease Awareness, Low Knowledge of Heart Attack Warning Signs Among Women
2. Connecticut Board Considers Warning About Risk Of Stroke Following Chiropractic Neck Manipulation
3. FDA Issues Warning on Key Asthma Drugs
4. Warning: Immigrating to North America may foster smoking in children
5. UNC study: Obese 3-year-olds show early warning signs for future heart disease
6. A Warning to Negligent Apartment Building Landlords in New York From Personal Injury Lawyer, David Perecman
7. Americans for Responsible Health Care Launch Radio Ads Targeting Seven Democrats, Warning The People Are Watching...
8. Not All Slings Are Created Equally: Baby Sling & Carrier Manufacturers Speak Out On Baby Sling Safety Warning
9. FDA Issues Warning on Fat-Melting Spa Injections
10. Warning Over Dangers of Used Racking Issued By Thistle Systems
11. Normal Blood Pressure in Male Teens a Warning Sign
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/28/2015)... ... August 28, 2015 , ... Northridge dentists Dr. Elyson and ... just $199, patients can currently receive a one hour treatment of this teeth whitening ... it includes a number of unique features that can turn teeth up to nine ...
(Date:8/28/2015)... , ... August 28, 2015 , ... ... announce its collaboration with coffee connoisseur and Emmy-nominated actress, Sofia Vergara, and unveil ... features revolutionary Thermal Flavor Extraction™ technology, which delivers a variety of sizes and ...
(Date:8/28/2015)... ... August 28, 2015 , ... ... to distributing health information technology innovation to transform quality and efficiency of healthcare ... survey will be de-identified and aggregated before being publicly shared to document progress ...
(Date:8/28/2015)... DC (PRWEB) , ... August ... ... Information Services, Inc.’s (AIS) Medicare-Medicaid Dual Eligibles Database have added comprehensive information ... CMS-backed alignment demonstration approved for a December 2015 launch; and Idaho’s partnership ...
(Date:8/28/2015)... ... August 28, 2015 , ... Popular review site ... millionaire dating sites . According to the listings, MillionaireMatch.com bags the ... category. , A spokesperson of Top5MillionaireDatingSites.com said, “This website has been ...
Breaking Medicine News(10 mins):Health News:Northridge Dentists Dr. Elyson and Dr. Assili Now Offer a Special Promotion on Zoom Teeth Whitening 2Health News:Sofia Vergara Partners With SharkNinja® To Launch The Ninja Coffee Bar™ 2Health News:Sofia Vergara Partners With SharkNinja® To Launch The Ninja Coffee Bar™ 3Health News:WEDI's The Sullivan Institute for Healthcare Innovation Releases Gaps in Care Survey 2Health News:AIS Duals Database: August Update Finds Two New Duals Programs in Rhode Island and Idaho 2Health News:Top5MillionaireDatingSites.com Publishes Its First List of Reviews of the Best Millionaire Dating Sites 2
... TeamStaff, Inc.,(Nasdaq: TSTF ) a national provider of ... notified by the Nasdaq Stock,Market that the Nasdaq Hearings ... the Nasdaq Global Market pending the effectiveness of the,Company,s ... was held on February 7, 2008. The decision of ...
... mg Delivers the Same, Medicine at the Same Dose ... Nearly 30 Million Frequent ... Beginning early March 2008,the nearly 30 million frequent heartburn ... them as retailers begin selling store,brand Omeprazole, a proton ...
... CHAPEL HILL, N.C., March 12 R&D structure ... is,essential to pharmaceutical companies. In a competitive market ... process increases -- the need to have an,optimized ... Discover the best-suited organizational structure that promotes rapid,growth, ...
... Calif., March 12 Omnicell,Inc. (Nasdaq: OMCL ), ... announced today that it has completed its $40.0,million program ... of,2,133,898 shares were repurchased at an average price of ... OMCL ) is a leading provider of systems and,software ...
... part of its ongoing effort to,give consumers information ... announced that four area hospitals have been,selected as ... Blue Distinction(R) is a nationwide program created ... care decisions and to work with their,health care ...
... Plans Participation in 2009 Medicare Advantage Open Enrollment in ... Florida Upon Approval of Applications, ... (Pink Sheets: PHYH), a developer of,health maintenance organizations (HMOs) in ... applications for the launch,of its pilot HMO in the state ...
Cached Medicine News:Health News:Nasdaq Hearings Panel Grants TeamStaff's Request for Continued Listing Subject to a Reverse Stock Split 2Health News:Nasdaq Hearings Panel Grants TeamStaff's Request for Continued Listing Subject to a Reverse Stock Split 3Health News:First Over-The-Counter Store Brand Omeprazole Offering in U.S. Market Creates New Option for Frequent Heartburn Sufferers 2Health News:First Over-The-Counter Store Brand Omeprazole Offering in U.S. Market Creates New Option for Frequent Heartburn Sufferers 3Health News:R&D Quality Excellence: Proven Tactics Optimize the R&D Quality Organizations of Pharmaceutical and Biotech Industries 2Health News:Omnicell Announces Completion of Its Common Stock Repurchase Plan 2Health News:Independence Blue Cross Announces Blue Distinction Centers for Complex and Rare Cancers(SM) in Philadelphia 2Health News:Independence Blue Cross Announces Blue Distinction Centers for Complex and Rare Cancers(SM) in Philadelphia 3Health News:Phyhealth Submits HMO Applications with Required Federal and State Agencies 2Health News:Phyhealth Submits HMO Applications with Required Federal and State Agencies 3
(Date:8/28/2015)... Shakti, LLC, today announced that it has changed its name ... Logo - http://photos.prnewswire.com/prnh/20150827/261551LOGO ... our transformation into a company focused on patent claim analysis ... validity." In ... the Company commenced a corporate re-branding initiative in order to ...
(Date:8/28/2015)... 2015  Perrigo Company plc ("Perrigo") (NYSE: PRGO ... acquisition of leading OTC brands from GSK in an ... is a clear demonstration of Perrigo,s unique ability to ... network spanning 36 countries.  Perrigo Chairman, ... "We are excited to complete this transaction, which clearly ...
(Date:8/28/2015)... PITTSBURGH , Aug. 28, 2015 ... announced that its shareholders have approved Mylan,s proposed ... ; TASE) and the related issuance of Mylan ... general meeting of shareholders held today. The transaction ... the extraordinary general meeting. In addition, the transaction ...
Breaking Medicine Technology:IP Shakti, LLC Changes Company Name to Prediqtus, LLC 2Perrigo Completes Acquisition of Leading Portfolio of OTC Brands from GSK 2Perrigo Completes Acquisition of Leading Portfolio of OTC Brands from GSK 3Perrigo Completes Acquisition of Leading Portfolio of OTC Brands from GSK 4Mylan Shareholders Overwhelmingly Approve Proposed Acquisition of Perrigo 2Mylan Shareholders Overwhelmingly Approve Proposed Acquisition of Perrigo 3Mylan Shareholders Overwhelmingly Approve Proposed Acquisition of Perrigo 4Mylan Shareholders Overwhelmingly Approve Proposed Acquisition of Perrigo 5Mylan Shareholders Overwhelmingly Approve Proposed Acquisition of Perrigo 6Mylan Shareholders Overwhelmingly Approve Proposed Acquisition of Perrigo 7Mylan Shareholders Overwhelmingly Approve Proposed Acquisition of Perrigo 8Mylan Shareholders Overwhelmingly Approve Proposed Acquisition of Perrigo 9
... Prime Therapeutics, one of the nation,s leading pharmacy ... offering a complete spectrum of options from rich benefits ... comes with a net drug spend guarantee of $47 ... predictable for plan sponsors," said Michael Showalter, Prime Chief ...
... an Informa business unit, and the world,s leading research ... from the 14th International Conference on Alzheimer,s Disease (ICAD ... continues to develop beta amyloid targeting drugs, amyloid targets ... warning for risk of Alzheimer,s. According to ...
Cached Medicine Technology:Prime Therapeutics Announces Pharmacy Offering with Guaranteed Net Spend Per Prescription 2Global Standardization for Alzheimer's Biomarkers Moves a Major Step Closer to Reality 2
Resorbable fixation system 1.5/2.0....
... By combining intra-operative ... imagery, Medtronic Surgical Navigation ... revolutionary product called SonoNav ... system built on the ...
... the two steps are performed in sequence ... single use disposable cartridge and placed in ... touches a button, and the cycle begins. ... Then the integral syringe pump concentrates fibrinogen, ...
Avitene Microfibrillar Collagen Hemostat (MCH) is used in surgical procedures as an adjunct to hemostasis when control of bleeding by ligature or conventional procedures is ineffective or impractical...
Medicine Products: