Navigation Links
WVU Doctor Works to Reduce Cancer Burden in Africa
Date:6/12/2009

MORGANTOWN, W.Va., June 12 /PRNewswire-USNewswire/ -- In 2010, cancer will be the single leading cause of death worldwide, overtaking chronic illnesses such as heart disease and stroke. Already cancer causes more deaths than HIV/AIDS, tuberculosis and malaria combined. Almost three-quarters of new cases will occur in developing countries, with more than a million cases in sub-Saharan Africa by 2020, according to World Health Organization projections.

Scot Remick, M.D., director of the Mary Babb Randolph Cancer Center at West Virginia University, is leading U.S. efforts to help prepare for the growing cancer burden in Third World nations. He heads the International Working Group of the National Cancer Institute's AIDS Malignancy Consortium, which has been instrumental in training doctors and building clinical trials for AIDS-related diseases in Uganda and Kenya.

"Most people don't realize that by 2010 cancer will be the single greatest cause of mortality worldwide," said Remick after returning from the May-June meeting of the American Society of Clinical Oncology, where he chaired an education session on the topic. "Anywhere from 15 to 20 percent of cancers are due to transmissible causes, and healthcare professionals in the industrialized world are likely to underestimate the role of infectious agents -- even though they constitute a significant burden."

Transmissible causes include viruses such as Epstein-Barr virus, human immunodeficiency virus (HIV), Hepatitis B and Hepatitis C viruses, and the human papillomavirus. Viruses may hit the developing world particularly hard, but rising rates of obesity and tobacco use are a factor, too.

"You're beginning to see Western influences on lifestyle, and this is creating impact on the cancer rate," Remick said.

Remick and an international team of researchers have just published results of the first clinical trial of its type in Africa -- a low-dose chemotherapy regimen for people with AIDS-related non-Hodgkin's lymphoma. The trial showed dramatic results -- a 6 percent mortality rate, compared with an expected 20 percent to 66 percent rate in the Kenyan and Ugandan populations studied.

The research team chose a low-dose chemotherapy regimen because it's vital that cancer therapies in sub-Saharan Africa be less myelotoxic -- or damaging to bone marrow -- than conventional treatment plans. Money, means and blood products may not exist in resource-challenged countries to counteract chemotherapy's potentially destructive effects on bone marrow.

Remick, senior researcher on the study published in the current issue of the Journal of Clinical Oncology, said the clinical trial represents a dozen years of work. Partners in the project are Case Western Reserve University in Ohio, Ohio State University, the Uganda Cancer Institute and Kenyatta National Hospital as well as medical schools in Uganda and Kenya.

The AIDS Malignancy Consortium will be promoting measures such as vaccination and other strategies aimed at preventing cancer as well as screening programs to encourage early diagnosis. Development of more low-dose chemotherapy trials is also on the agenda.

"The hope is that, as things will evolve, our efforts will be less about awareness and advocacy and more about action," Remick said.

This news release was issued on behalf of Newswise(TM). For more information, visit http://www.newswise.com.


'/>"/>
SOURCE West Virginia University Health Sciences Center
Copyright©2009 PR Newswire.
All rights reserved

Related medicine news :

1. UK junior doctors gaining less experience of common procedures
2. Doctors Often Miss High Blood Pressure in Kids
3. One-fourth of HIV patients believe their doctors stigmatize them
4. Annual flu shot cuts need for doctors visits, hospitalization among children
5. Teens need to see their doctors more often
6. Doctors and medical ethicist discuss whether doctors should participate in capital punishment
7. Doctors and Medical Ethicist Discuss Whether Doctors Should Participate in Capital Punishment
8. Figure Skater Peggy Fleming, HealthSaver Says: Take Pains For Back Strains, 2nd Most Common Doctor Complaint
9. Research says doctors gender may hinder early diagnosis of heart disease in women
10. South Texas Doctors Report More Severe Cases of Community Staph Super Bug Hospitalizing Children
11. Maimonides Expands Circulation of Physicians Practice Journal to Staten Island Doctors
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/2/2016)... ... December 02, 2016 , ... ... needy individuals and families from eight different sites throughout Miami-Dade and Broward counties. ... 1,000 volunteers worked very hard on Thanksgiving morning by putting together individual meals ...
(Date:12/2/2016)... ... 02, 2016 , ... ‘Tis the season for giving! Today, 20 creative teams ... Family Partnership and the Drug Enforcement Administration as part of the National Red Ribbon ... winning schools who decorated their campuses with this year’s Red Ribbon Week theme: “YOLO. ...
(Date:11/30/2016)... ... November 30, 2016 , ... "I hate when the mixture of ... my teeth," said an inventor from Bridgewater, N.J. "I thought that there had to ... device." , He developed the patent-pending DEFLECTOR to prevent saliva and toothpaste from running ...
(Date:11/30/2016)... ... November 30, 2016 , ... ... treatment has announced the opening of a new residential mental health treatment program ... mental health issues such as severe anxiety, depression, bi-polar disorder, and other related ...
(Date:11/30/2016)... ... November 30, 2016 , ... The Clinical ... that the FDA Binding Guidance goes into effect next month. Sponsors whose studies ... the FDA Data Standards Catalog. The current FDA Data Standards Catalog specifies the ...
Breaking Medicine News(10 mins):
(Date:12/2/2016)... 2016 bioLytical Laboratories, un líder mundial en test rápidos ... HIV Self Test , a los miembros de la Kenya Pharmaceutical Association. ... ... INSTI HIV Self Test! (PRNewsFoto/bioLytical Laboratories) ...      (Photo: http://photos.prnewswire.com/prnh/20161201/444905 ) bioLytical fue invitada por la ...
(Date:12/2/2016)... DUBLIN , Dec 2, 2016 Research ... Market Size, Share, Development, Growth and Demand Forecast to 2022" report ... , , ... revenue of $6 billion in 2015, and it is expected to grow ... ultrasound segment is expected to witness faster growth during the forecast period, ...
(Date:12/2/2016)... , December 2, 2016 On ... Committee honored excellence in research, development and innovation in ... gala dinner was held in the presence of Sergey ... Russian Federation , Natalia Sanina, First ... Mikhail Murashko , Head of Roszdravnadzor, National Service of ...
Breaking Medicine Technology: