Navigation Links
WTC workers exposed earlier to dust cloud have higher risk of atherosclerotic lesions
Date:11/16/2011

In the first study using magnetic resonance imaging (MRI) to evaluate cardiovascular risk in World Trade Center (WTC) first responders, researchers from Mount Sinai School of Medicine have found that the responders who experienced high levels of exposure to the initial dust cloud on September 11, 2001, demonstrate high-risk features of atherosclerosis (plaque in arteries). The data was presented at the American Heart Association's Scientific Sessions 2011 in Orlando, Florida.

Mary Ann McLaughlin, MD, MPH, Associate Professor of Medicine is the primary investigator for this study and has been evaluating the cardiovascular health of the WTC responders since 2007. In addition to the current study, her research has shown more impaired cardiac relaxation and coronary calcification in responders at Ground Zero, compared with the general population.

First author, Venkatesh Mani, PhD, and colleagues, used MRI to evaluate the blood vessels of 19 responders exposed to the high levels of particulate matter from the dust cloud, and 12 exposed to the lower levels. They found that WTC workers who were exposed to the initial dust cloud had higher blood vessel formation in their artery plaque compared to people with lower exposure. Co-investigator, Simonette Sawit, MD also demonstrated impaired vascular reactivity, or dysfunction of the inner lining of blood vessels, in those with higher dust exposure. This dysfunction may accelerate the progression of atherosclerosis. The Mount Sinai team discovered this association in WTC workers independent of other clinical factors.

"Using noninvasive MRI imaging, we were able to see a significant impact of the events of 9/11 on the cardiovascular health of the brave men and women who responded that day," said Zahi Fayad, PhD, Professor of Radiology, and Medicine in the Division of Cardiology, and the Director of the Translational and Molecular Imaging Institute at Mount Sinai School of Medicine. "Now that we have visualized the risk and early development of vascular lesions, in a subset of subjects, we look forward to studying the use of imaging in the greater patient population."

"This study defines physiologic change associated with greater exposure to the dust cloud at the WTC site," said Dr. McLaughlin. "We are currently evaluating other predictors of cardiovascular risk in this population to gain a better understanding of the impact of particulate matter exposure on cardiovascular health."


'/>"/>

Contact: Mount Sinai Press Office
newsmedia@mssm.edu
212-241-9200
The Mount Sinai Hospital / Mount Sinai School of Medicine
Source:Eurekalert

Related medicine news :

1. Smithfield, United Food and Commercial Workers Union, and Food Networks Paula Deen to Deliver 150,000 Servings of Protein to San Francisco Food Bank
2. Hope Phones, IntraHealth and FrontlineSMS:Medic Collaborate on Phone Donation Campaign to Support Health Workers in Africa
3. March Is National Social Work Month: Social Workers Work to Inspire Community Action While Facing Threats of Budget Cuts
4. Galfand Berger Wins Important Case for Injured Workers in Pennsylvania
5. Teamsters, Religious Leaders Call on Ascension Health to Respect Rights of Workers, Patients and Communities
6. Free Seminars to Help Employers Prevent Noise-Induced Hearing Loss Among Workers Set for Phoenix, Reno, Salt Lake City, Denver in May
7. Mount Sinai researchers are the first to identify heart abnormalities in World Trade Center workers
8. New Research from EBRI: Older Workers Trending Toward More Part-Time Work
9. Georgia Firm Adds Medical Travel to Cut Costs, Provide Options for Workers
10. Looming unemployment harms older workers health
11. Shift workers at more risk for irritable bowel syndrome, U-M study says
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/20/2017)... Missoula, MT (PRWEB) , ... January 20, 2017 , ... Spectrum Aquatics Launches New ADA ... use, saving deck space. Since the lift is mounted on wheels, it can be wheeled ... a lock down kit, to fasten to the deck. "We have transformed the feedback from ...
(Date:1/20/2017)... ... ... Sports Nutrition LLC, an American company devoted to developing high-quality nutritional supplements for people ... in Hilton Head, SC. , Bionic Sports Nutrition manufactures its entire line of ... clients at reasonable prices. At the ECRM trade show, it had a unique chance ...
(Date:1/20/2017)... ... , ... "TransFlare 4K Mystique comes with 44 colorful mysterious transitions that are ... Austin - CEO of Pixel Film Studios. , TransFlare 4K Mystique contains 44 ... flare and light leak transitions have a very high-dynamic range for super smooth falloff. ...
(Date:1/20/2017)... (PRWEB) , ... January 20, 2017 , ... “I Forgive You”: a fine examination ... “I Forgive You” is the creation of published author, Stephen Miller, who, for over ten ... has gracefully given to him. Born in Trinidad and Tobago, he has been serving the ...
(Date:1/20/2017)... (PRWEB) , ... January 20, 2017 , ... “The Land ... brings attention to the issue of world hunger, and shares the simple and achievable ... Brubaker, devoted husband and member of the Fairview Missionary Church in Angola, Indiana where ...
Breaking Medicine News(10 mins):
(Date:1/21/2017)... -- ResMed (NYSE: RMD ), BMC ( Beijing, ... ) today announced they have agreed on a global settlement ... permitted to sell their existing products in exchange for royalty payments ... 3B to close the Florida litigation between ... liability or wrongdoing by any party. The five-year ...
(Date:1/21/2017)... YORK , Jan. 20, 2017  Faruqi & Faruqi, ... KemPharm, Inc. ("KemPharm" or the "Company") (NASDAQ: KMPH ... the Company and certain officers and directors and underwriters of ... to seek the role of lead plaintiff. The ... District Court for Johnson County ...
(Date:1/20/2017)... Research and Markets has announced the addition of the ... to their offering. ... This research service on the global pharmaceutical stability testing market ... of the key participants in the market. The ... 2020. The market is expected to grow at a CAGR of ...
Breaking Medicine Technology: