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WSU researcher creates patented personalized therapy that causes cancer cells to kill themselves
Date:2/28/2011

but that's a tradeoff someone suffering from metastatic cancer and given a limited prognosis may accept in exchange for becoming cancer-free.

To date, Dr. Rosner has demonstrated cancer cell kill rates of 70 to 100 percent with his first generation of "gene suicide therapy." To further increase the killing efficiency, he has recently designed a second generation of constructs. In the near future he intends to test the therapy in an animal model, an intermediate step required before moving the treatment into clinical trial.

"Although this has been tested on melanoma cell lines, Dr. Rosner's approach can be tailored to other types of tumors," said Darius Mehregan, M.D., the Hermann Pinkus Chair of the Department of Dermatology. "I think it is important for other researchers in the Wayne State University system to be aware of possibilities to collaborate, and for the pharmaceutical industry to be aware of the economic potential of this novel technology."


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Contact: Julie O'Connor
julie.oconnor@wayne.edu
313-577-8845
Wayne State University - Office of the Vice President for Research
Source:Eurekalert

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