Navigation Links
Vulnerability to Anthrax Varies Widely: Study
Date:2/6/2012

MONDAY, Feb. 6 (HealthDay News) -- People's susceptibility to anthrax toxin is determined by their genes and can vary greatly among individuals, a new study says.

Anthrax is an infectious disease widely regarded as a potential bioterrorism weapon.

Stanford University School of Medicine researchers analyzed immune cells from 234 people and found that the cells of three of the people were virtually insensitive to anthrax toxin, while the cells of others were hundreds of times more sensitive than those of other people.

The findings could help lead to new treatments and could also have important implications for U.S. national security, according to a university news release. For example, people known to be more resistant could act as first-line responders in an anthrax bioterrorism attack.

The study appears online Feb. 6 in the journal Proceedings of the National Academy of Sciences.

"This research offers an important proof of principle. They've showed that genetically determined variations in the level of expression of a human protein can influence the susceptibility of host cells to anthrax toxin," Dr. David Relman said in the release.

Relman is a professor of microbiology and immunology and of medicine at Stanford, chair of the Institute of Medicine's Forum on Microbial Threats and a member of the U.S. Department of Health and Human Service's National Science Advisory Board for Biosecurity. He was not involved in the study.

"The findings also provide a possible means for predicting who is likely to become seriously ill after exposure, which could be extremely useful when faced with a large number of exposed people, such as was the case during the 2001 anthrax attacks," Relman said. (A week after the 9/11 attacks, letters carrying anthrax spores were mailed within the United States, killing five people and infecting 17 others.)

"Finally, they could lead to the development of novel treatment strategies, perhaps by blocking the interaction between the toxin and the receptor, or by down-regulating its expression," he added.

More information

The U.S. Centers for Disease Control and Prevention has more about anthrax.

-- Robert Preidt

SOURCE: Stanford University, news release, Feb. 3, 2012


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Signaling pathways point to vulnerability in breast cancer stem cells
2. PTSD: The serotonin system influences vulnerability and treatment
3. Anthrax Vaccine Shows Promise in Monkeys
4. Anthrax capsule vaccine protects monkeys from lethal infection
5. Natural killer cells could be key to anthrax defense
6. Community storage of anthrax-preventing antibiotics should be determined by state
7. Bacillus anthracis and Anthrax
8. Poll: Hypothetical anthrax attack and antibiotics
9. Rate of follow-up surgeries after partial mastectomy varies greatly
10. Treatment of rectal cancer varies enormously between different European countries
11. Thyroid cancer treatment varies by hospital, U-M study finds
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Vulnerability to Anthrax Varies Widely: Study
(Date:2/5/2016)... UT (PRWEB) , ... February 05, 2016 , ... Today, ... Nutrition , announced that the much-anticipated feature with author Jahnavi Foster, specialist in healthy ... Amateur TV Network. , Each week, on his weekly Whole-Food Warrior TV show, Frank ...
(Date:2/5/2016)... MN (PRWEB) , ... February 05, 2016 , ... The ... at the Day Block Event Center in Minneapolis, Minn. Triumph Over Parkinson’s will fund ... Larry Schneiderman, owner of Schneiderman’s Furniture, lives with Parkinson’s disease and is the architect ...
(Date:2/5/2016)... ... February 05, 2016 , ... Francisco Canales, MD and Heather ... Napa Valley office. The technique utilizes the body’s own healing abilities to quickly ... Furnas, are part of only a select few cosmetic surgeons bringing this procedure ...
(Date:2/5/2016)... ... February 05, 2016 , ... Freed-Hardeman University President Joe A. ... a joint enrollment and degree completion agreement. The agreement, which begins with ... at FHU|Dickson. , The agreement allows students to be jointly admitted to ...
(Date:2/5/2016)... ... February 05, 2016 , ... The Lymphoma Research Foundation (LRF) ... and serving the lymphoma community through a comprehensive series of education programs, outreach ... Wine Tasting Event at the La Gorce Country Club in Miami Beach on ...
Breaking Medicine News(10 mins):
(Date:2/5/2016)... 5, 2016  Zimmer Biomet Holdings, Inc. (NYSE and ... announced underwritten secondary offering of 11,027,558 shares of its ... affiliates of Blackstone and Goldman Sachs.  The shares are ... of $96.45 per share. The selling stockholders will receive ... Biomet nor any of its directors, officers or other ...
(Date:2/5/2016)... 2016 Site Profile: --> ... - The Speech Recognition People, announced their latest primary healthcare case ... care, reduce turnaround times and to save the practice money. ... since 2013 Challenge: --> ,- Wirral CCG ... - Six doctors ,- Wirral CCG ,- VoicePower client since 2013 ...
(Date:2/4/2016)... For hospitals considering enrollment in the Federal ... the program, the Health Resources and Services Administration,s (HRSA) ... Mega-Guidance , could have significant impact on plans and ... 2016. Essential Insights , Daniel Neal, ... the Mega-Guidance,s key proposed changes, including a new requirement ...
Breaking Medicine Technology: