Navigation Links
Vulnerability to Anthrax Varies Widely: Study
Date:2/6/2012

MONDAY, Feb. 6 (HealthDay News) -- People's susceptibility to anthrax toxin is determined by their genes and can vary greatly among individuals, a new study says.

Anthrax is an infectious disease widely regarded as a potential bioterrorism weapon.

Stanford University School of Medicine researchers analyzed immune cells from 234 people and found that the cells of three of the people were virtually insensitive to anthrax toxin, while the cells of others were hundreds of times more sensitive than those of other people.

The findings could help lead to new treatments and could also have important implications for U.S. national security, according to a university news release. For example, people known to be more resistant could act as first-line responders in an anthrax bioterrorism attack.

The study appears online Feb. 6 in the journal Proceedings of the National Academy of Sciences.

"This research offers an important proof of principle. They've showed that genetically determined variations in the level of expression of a human protein can influence the susceptibility of host cells to anthrax toxin," Dr. David Relman said in the release.

Relman is a professor of microbiology and immunology and of medicine at Stanford, chair of the Institute of Medicine's Forum on Microbial Threats and a member of the U.S. Department of Health and Human Service's National Science Advisory Board for Biosecurity. He was not involved in the study.

"The findings also provide a possible means for predicting who is likely to become seriously ill after exposure, which could be extremely useful when faced with a large number of exposed people, such as was the case during the 2001 anthrax attacks," Relman said. (A week after the 9/11 attacks, letters carrying anthrax spores were mailed within the United States, killing five people and infecting 17 others.)

"Finally, they could lead to the development of novel treatment strategies, perhaps by blocking the interaction between the toxin and the receptor, or by down-regulating its expression," he added.

More information

The U.S. Centers for Disease Control and Prevention has more about anthrax.

-- Robert Preidt

SOURCE: Stanford University, news release, Feb. 3, 2012


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Signaling pathways point to vulnerability in breast cancer stem cells
2. PTSD: The serotonin system influences vulnerability and treatment
3. Anthrax Vaccine Shows Promise in Monkeys
4. Anthrax capsule vaccine protects monkeys from lethal infection
5. Natural killer cells could be key to anthrax defense
6. Community storage of anthrax-preventing antibiotics should be determined by state
7. Bacillus anthracis and Anthrax
8. Poll: Hypothetical anthrax attack and antibiotics
9. Rate of follow-up surgeries after partial mastectomy varies greatly
10. Treatment of rectal cancer varies enormously between different European countries
11. Thyroid cancer treatment varies by hospital, U-M study finds
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Vulnerability to Anthrax Varies Widely: Study
(Date:10/13/2017)... ... October 13, 2017 , ... PurhealthRX , a leading Health ... technology. Applying the Purzorb™process to full spectrum CBD oil will revolutionize the rapidly growing ... form that can be easily incorporated into liquid products, while reducing costs to end ...
(Date:10/13/2017)... ... 13, 2017 , ... The Visiting Nurse Association (VNA) of Somerset Hills is ... vendors and unique items from across the nation, this holiday-themed event will raise funds ... by the VNA. The boutique will be open Saturday, November 4 (10:00 a.m. ...
(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... ... DevOps and Agile Software Development, has been awarded a contract by the Center ... Purchase Agreement (BPA) aims to accelerate the enterprise use of Agile methodologies in ...
(Date:10/12/2017)... ... , ... Planet Fitness, one of the largest and fastest growing franchisors and ... flagship location in Covington, LA at 401 N. U.S. Highway 190, in January of ... Depot in the Holiday Square shopping center. Its location allows it to serve both ...
(Date:10/12/2017)... Rockville, Maryland (PRWEB) , ... October 12, 2017 ... ... a magnetic drug delivery system that we intend to develop to enable prevention ... regimens can lead to severe hearing loss, especially in pediatric patients. For cisplatin, ...
Breaking Medicine News(10 mins):
(Date:10/12/2017)... 12, 2017 West Pharmaceutical Services, Inc. ... for injectable drug administration, today announced that it will ... on Thursday, October 26, 2017, and will follow with ... expectations at 9:00 a.m. Eastern Time. To participate on ... The conference ID is 94093362. ...
(Date:10/11/2017)... 11, 2017  True Health, a leader in ... effort during National Breast Cancer Awareness month to ... Research recently ... that more than 10 million American women are ... BRCA1 or BRCA2 and have not had testing. These ...
(Date:10/10/2017)... , Oct. 10, 2017   West Pharmaceutical Services, ... solutions for injectable drug administration, today shared the results ... Adapter for improving the intradermal administration of polio vaccines. ... Vaccination Summit in May 2017 by Dr. Ondrej ... Department, World Health Organization (WHO), and recently published in ...
Breaking Medicine Technology: