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Voices Against Brain Cancer Comments on Recent Discovery in Ongoing Brain Cancer Research
Date:6/25/2013

New York, NY (PRWEB) June 25, 2013

On June 25, Voices Against Brain Cancer, an organization dedicated to brain cancer research and advocacy, comments on the recent discovery of a combination of viruses that has proven to be effective against the deadliest forms of brain tumors.

According to an article on ScienceDaily.com, a combination of the myxoma virus and the immune suppressant rapamycin can kill glioblastoma multiforme, the most common and deadliest malignant brain tumor. This was reported by research performed by the Moffitt Cancer Center.

Peter A. Forsyth, M.D., of Moffitt’s Neuro-Oncology Program, says the combination “has been shown to infect and kill both brain cancer stem cells and differentiated compartments of glioblastoma multiforme.” This finding means that current barriers to treating the disease may be overcome. For example, some brain cancer patients experience drug resistance to existing therapies, which has become an obstacle in treatment. Forsyth says, “Oncolytic viruses that infect and break down cancer cells offer promising possibilities for overcoming resistance to targeted therapies.”

The authors of the study explain that the combination of viruses have the potential to start a “multipronged attack” on a tumor, with the possibility of killing cancer cells directly through viral infection and inducing the immune system to attack the tumor. There have been several oncolytic viruses that have been tested and show promise against malignant gliomas.

Forsyth says, “We found that myxoma virus combined with rapamycin is a potentially useful combination. The idea that cancer cells can be killed by a harmless virus is an exciting prospect for therapy.”

Michael Klipper, Chairman of Voic
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