Navigation Links
Voices Against Brain Cancer Comments on New Discovery Made by Researchers in Regards to the Tie between Brain Cancer and Genetics

New York, NY (PRWEB) June 07, 2013

On June 7, Voices Against Brain Cancer, an organization dedicated to brain cancer research and advocacy, comments on the recent discovery made by researchers in regards to the tie between brain cancer and genetics.

According to a article, the genetic traits of glial cells, the cells which give rise to the most common form of malignant brain cancer found in humans, have been identified by a team of researchers led by University of Rochester Medical Center (URMC) neurologist, Dr. Steven Goldman.

Goldman, the senior author of the study and the co-director of the URMC Center for Translational Neuromedicine said in a statement released this week, “This study identifies a core set of genes and pathways that are deregulated during both the early and late stages of tumor progression. By virtue of their marked difference from normal cells, these genes appear to comprise a promising set of targets for therapeutic intervention.”

Brain tumors, also known as gliomas, originate from these glial cells. They progress in severity as time passes and ultimately turn into glioblastomas, which are highly invasive tumors that are difficult to treat making them almost always fatal. Presently, these glioblastomas are treated with a combination of surgery, radiation and chemotherapy. Although, these procedures do delay the cancer’s progression, they ultimately prove to be ineffective at fighting the tumor. However, this new study, published in the journal Cell Reports, could change this.

In the study, researchers took human tissue samples that represented the three initial stages of cancer. They were able to identify and isolate “the cancer-inducing stem cells.” They proceeded to compare the gene expression profiles of these cancer stem cells to those of normal glial progenitor cells. They hoped to be able to “determine the earliest point in which genetic changes associated with cancer formation occurs and identify the genes that were both unique to the cancer-causing stem cells and expressed at every stage of the disease’s progression.”

URMC states “the scientists identified a small set of genes in the cancerous glioma progenitor cells that were over-expressed at all stages of malignancy.” Goldman and his team targeted a gene that was highly over-expressed, known as SIX1. When scientists blocked the gene’s expression, the cancer cells stopped growing and the implanted tumors actually began to shrink.

Goldman went on to say, “This study gives us a blueprint to develop new therapies. We can now devise a strategy to systematically and rationally analyze – and eliminate – glioma stem and progenitor cells using compounds that may selectively target these cells, relative to the normal glial progenitors from which they derive.”

Michael Klipper, chairman of Voices Against Brain Cancer, an organization dedicated to brain cancer research and advocacy elaborates on this exciting new discovery. “When scientists are able to target certain brain cancer indicators, then they will eventually be able to effectively treat gliomas. This is huge for the entire brain cancer community and gives us hope that there will one day be a cure.”

VABC has a wide variety of initiatives in place for brain cancer research, awareness and support. The organization’s research grants fund cutting-edge research programs that will have a monumental impact on the diagnosis and treatment of brain cancer. VABC currently funds research at several esteemed institutions such as Brookhaven National Laboratory, Cleveland Clinic, Columbia, Cornell, Duke, Harvard, John Hopkins, Memorial Sloan-Kettering and Yale, to name a few.

VABC's mission is to find a cure for brain cancer by advancing scientific research, increasing awareness within the medical community and supporting patients, their families and caregivers afflicted with this devastating disease.

For press inquiries, please contact: 5W Public Relations


Read the full story at

Source: PRWeb
Copyright©2012 Vocus, Inc.
All rights reserved

Related medicine news :

1. Voices Against Brain Cancer Comments on New Potential Development in Brain Cancer Treatment
2. Voices Against Brain Cancer Commends Family for their Ongoing Efforts to Spread Brain Cancer Awareness
3. Avatar therapy helps silence voices in schizophrenia
4. Voices Against Brain Cancer Comments on Study that Shows Cold Plasma’s Success Against Brain Cancer Cells
5. Voices Against Brain Cancer Commends Young Man for Raising Money for Brain Cancer Despite Fighting His Own Battle
6. Voices Against Brain Cancer Commends Mother for the Way She Honors Her Daughter’s Death
7. Voices Against Brain Cancer Applauds Mother For Starting Riah’s Rainbow Organization
8. Voices Against Brain Cancer Commends Young Brain Tumor Patient for her Appearance on Popular Trivia Game Show
9. Voices Against Brain Cancer Commends Woman on How She is Keeping Her Husband’s Memory Alive
10. Voices Against Brain Cancer Congratulates Alec Panici on Being Recognized as Caregiver of the Year
11. Voices Against Brain Cancer Comments on New Discovery That May Help MDs Diagnose and Treat Certain Pediatric Brain Tumors
Post Your Comments:
(Date:6/25/2016)... Oklahoma City, Oklahoma (PRWEB) , ... June 25, ... ... to helping both athletes and non-athletes recover from injury. Recently, he has implemented ... for the Oklahoma City area —Johnson is one of the first doctors to ...
(Date:6/24/2016)... ... 24, 2016 , ... Those who have experienced traumatic events may suffer from ... avenues, such as drug or alcohol abuse, as a coping mechanism. To avoid this ... coping following a traumatic event. , Trauma sufferers tend to feel a range of ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... Global law ... magazine’s 2016 Legal Elite. The attorneys chosen by their peers for this recognition are ... , Seven Greenberg Traurig Shareholders received special honors as members of this year’s Legal ...
(Date:6/24/2016)... , ... June 24, 2016 , ... People across the ... Genome magazine’s Code Talker Award, an essay contest in which patients and their families ... to be presented at the 2016 National Society of Genetic Counselors (NSGC) Annual Education ...
(Date:6/24/2016)... , ... June 24, 2016 , ... ... actively feeding the Frederick area economy by obtaining investment capital for emerging technology ... past 2½ years that have already resulted in more than a million dollars ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... Belgium , June 24, 2016 /PRNewswire/ ... announced the appointment of Dr. Edward Futcher ... a Non-Executive Director, effective June 23, 2016.Dr. Futcher ... and Nominations and Governance Committees.  As a non-executive ... provide independent expertise and strategic counsel to VolitionRx ...
(Date:6/23/2016)...  MedSource announced today that it has selected ... of choice.  This latest decision demonstrates MedSource,s commitment ... clients by offering a state-of-the-art electronic data capture ... as the EDC platform of choice in exchange ... has long been a preferred EDC platform by ...
(Date:6/23/2016)... , June 23, 2016 Any dentist who ... challenges of the current process. Many of them do not ... the technical difficulties and high laboratory costs involved. And those ... offer it at such a high cost that the majority ... Dr. Parsa Zadeh , founder of Dental ...
Breaking Medicine Technology: