Navigation Links
Vitamins may hitch a protected ride on corn starch

Vitamins and medications may one day take rides on starch compounds creating stable vitamin-enriched ingredients and cheaper controlled-release drugs, according to Penn State food scientists.

The technique may offer drug and food companies a less expensive, more environmentally friendly alternative in creating, among other products, medications and food supplements.

In a series of experiments, researchers formed pockets with corn starch and a fatty acid ester to carry oil soluble vitamins, such as vitamin A and vitamin C, into the body, according to Gregory Ziegler, professor, food sciences.

Heat and acids can harm or destroy vitamins. The starch molecule forms a protective pocket around the vitamins as they travel through the highly acidic stomach and into the small intestines, where they can be absorbed into the blood stream.

To form the pocket, the researchers, who released their findings in a recent issue of Carbohydrate Polymers, used a type of corn starch called high amylose maize starch. When amylose comes into contact with fatty acids esters of vitamin A, for example, it creates a coil with an internal wall that repels water -- hydrophobic -- and an exterior wall that attracts water -- hydrophilic. The oil-soluble molecules automatically move into the coil that encapsulates the medication or vitamin.

"There's an ideal size and the real work is to get the right balance of the hydrophilic and hydrophobic properties," said Ziegler, who worked with Ursula V. Lay Ma, graduate student, and John D. Floros, professor, food sciences.

According to Ziegler, there are several benefits for using starches as hosts for delivering drugs and vitamins. Because starches are common, biodegradable and easily absorbed by the body, using corn starch could be inexpensive and better for the environment.

The pharmaceutical industry uses other ingredients and techniques to create inclusion complexes, said Ziegler. For example, cyclodextrin complexes -- donuts of sugar molecules -- form in a similar way to deliver controlled-release substances, such as Ibuprofen. Ziegler said that because the cavity in starch is a different size than that of cyclodextrin, it can increase the size range of molecules that can be encapsulated.

Corn starch could be used in a variety of other applications, including those outside the pharmaceutical and food industries, such as in make-up, containers and even optical and electronic devices, according to Ziegler. "We have more work and research to do," Ziegler said. "The trick is how can we set this up so we can do it simply."


Contact: Matt Swayne
Penn State

Related medicine news :

1. Vitamins C and E linked to metabolic syndrome in low-income Ecuadorians
2. Study Finds Vitamins E and C Dont Reduce Cataract Risk in Men
3. B vitamins and the aging brain examined
4. Vitamins needed to help celiacs stave off bone disease
5. Vitamins D, E Might Help Maintain Brain Health
6. Vitamins for Life Inventory Extended to Wellness Products, Higher Nature Supplements
7. More Evidence That B Vitamins Alone Wont Counter Heart Risks
8. Rich Vitamins Proves Taking Vitamins Doesn't Have to be a Pill with New alternaVites
9. Natural Health Online Retailer Expands Inventory to Meet UK Demands
10. Publix Pharmacy Now Offers Pill Glide, an Innovative New Way for Children and Adults to Take Vitamins, Supplements and Medications
11. Announcing NutriVite, Liquid Multivitamin Shots - Welcome to the Future of Vitamins
Post Your Comments:
(Date:10/13/2017)... ... 13, 2017 , ... Lori R. Somekh, founder of the Law Office ... of elder law and special needs planning attorneys. “Membership in ElderCounsel helps our office ... forum to network with elder law attorneys nationwide,” said Somekh. , ElderCounsel ...
(Date:10/13/2017)... BASKING RIDGE, N.J. (PRWEB) , ... October 13, 2017 , ... ... second annual Holly Day Market. Featuring a collection of specialty vendors and unique items ... myriad of personalized and quality-focused health and wellness services offered by the VNA. ...
(Date:10/13/2017)... , ... October 13, 2017 , ... Yisrayl Hawkins, Pastor ... that explains one of the most popular and least understood books in the Holy ... and puzzling descriptions that have baffled scholars for centuries. Many have tossed it off ...
(Date:10/13/2017)... ... 13, 2017 , ... “The Journey: From the Mountains to the Mission Field”: ... souls in the Philippines. “The Journey: From the Mountains to the Mission Field” is ... Bible. She has taught all ages and currently teaches a class of ladies at ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... treating sleep apnea using cutting-edge Oventus O2Vent technology. As many as ... disorder characterized by frequent cessation in breathing. Oral appliances can offer significant relief ...
Breaking Medicine News(10 mins):
(Date:10/2/2017)... Oct. 2, 2017 Halo Labs announces the European launch ... called the HORIZON at MIBio 2017 in Cambridge, U.K ... visible particulate matter in biopharmaceutical samples with unprecedented speed and sensitivity ... novel technique Backgrounded Membrane Imaging. ... The HORIZON subvisible particle analysis system ...
(Date:9/27/2017)... Israel and NEW YORK , Sept. 27, ... with mobile health and big data solutions, today announced that its MyDario ... Please check your local TV listings for when The Dr. Oz Show ... ... season this month. ...
(Date:9/22/2017)... DIEGO , Sept. 22, 2017 AVACEN ... medical device is now successfully helping those with the ... Fibromyalgia diagnosed Amanda in Essex, ... dressed and washing my hair, experiencing no sleep at ... in painful spasm… I cannot recommend [the AVACEN 100] ...
Breaking Medicine Technology: