Navigation Links
Vitamins may hitch a protected ride on corn starch
Date:5/11/2011

Vitamins and medications may one day take rides on starch compounds creating stable vitamin-enriched ingredients and cheaper controlled-release drugs, according to Penn State food scientists.

The technique may offer drug and food companies a less expensive, more environmentally friendly alternative in creating, among other products, medications and food supplements.

In a series of experiments, researchers formed pockets with corn starch and a fatty acid ester to carry oil soluble vitamins, such as vitamin A and vitamin C, into the body, according to Gregory Ziegler, professor, food sciences.

Heat and acids can harm or destroy vitamins. The starch molecule forms a protective pocket around the vitamins as they travel through the highly acidic stomach and into the small intestines, where they can be absorbed into the blood stream.

To form the pocket, the researchers, who released their findings in a recent issue of Carbohydrate Polymers, used a type of corn starch called high amylose maize starch. When amylose comes into contact with fatty acids esters of vitamin A, for example, it creates a coil with an internal wall that repels water -- hydrophobic -- and an exterior wall that attracts water -- hydrophilic. The oil-soluble molecules automatically move into the coil that encapsulates the medication or vitamin.

"There's an ideal size and the real work is to get the right balance of the hydrophilic and hydrophobic properties," said Ziegler, who worked with Ursula V. Lay Ma, graduate student, and John D. Floros, professor, food sciences.

According to Ziegler, there are several benefits for using starches as hosts for delivering drugs and vitamins. Because starches are common, biodegradable and easily absorbed by the body, using corn starch could be inexpensive and better for the environment.

The pharmaceutical industry uses other ingredients and techniques to create inclusion complexes, said Ziegler. For example, cyclodextrin complexes -- donuts of sugar molecules -- form in a similar way to deliver controlled-release substances, such as Ibuprofen. Ziegler said that because the cavity in starch is a different size than that of cyclodextrin, it can increase the size range of molecules that can be encapsulated.

Corn starch could be used in a variety of other applications, including those outside the pharmaceutical and food industries, such as in make-up, containers and even optical and electronic devices, according to Ziegler. "We have more work and research to do," Ziegler said. "The trick is how can we set this up so we can do it simply."


'/>"/>

Contact: Matt Swayne
mls29@psu.edu
814-865-9481
Penn State
Source:Eurekalert

Related medicine news :

1. Vitamins C and E linked to metabolic syndrome in low-income Ecuadorians
2. Study Finds Vitamins E and C Dont Reduce Cataract Risk in Men
3. B vitamins and the aging brain examined
4. Vitamins needed to help celiacs stave off bone disease
5. Vitamins D, E Might Help Maintain Brain Health
6. Vitamins for Life Inventory Extended to Wellness Products, Higher Nature Supplements
7. More Evidence That B Vitamins Alone Wont Counter Heart Risks
8. Rich Vitamins Proves Taking Vitamins Doesn't Have to be a Pill with New alternaVites
9. Natural Health Online Retailer VitaminsForLife.co.uk Expands Inventory to Meet UK Demands
10. Publix Pharmacy Now Offers Pill Glide, an Innovative New Way for Children and Adults to Take Vitamins, Supplements and Medications
11. Announcing NutriVite, Liquid Multivitamin Shots - Welcome to the Future of Vitamins
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2016)... (PRWEB) , ... June 26, 2016 , ... Pixel Film ... Pro X. , "Film editors can give their videos a whole new perspective by ... Austin - CEO of Pixel Film Studios. , ProSlice Levels contains over 30 ...
(Date:6/25/2016)... ... June 25, 2016 , ... Experts from the American ... Annual Research Meeting June 26-28, 2016, at the Hynes Convention Center in Boston. ... including advance care planning, healthcare costs and patient and family engagement. , AIR ...
(Date:6/25/2016)... ... June 25, 2016 , ... First Choice Emergency Room , the largest ... as the Medical Director of its new Mesquite-Samuell Farm facility. , “We are ... Mesquite location,” said Dr. James M. Muzzarelli, Executive Medical Director of First Choice Emergency ...
(Date:6/25/2016)... ... , ... Conventional wisdom preaches the benefits of moderation, whether it’s a matter ... bar too high can result in disappointment, perhaps even self-loathing. However, those who set ... , Research from PsychTests.com reveals that behind the tendency to set low ...
(Date:6/24/2016)... , ... June 24, 2016 , ... Marcy was in a crisis. Her son James, ... out at his family verbally and physically. , “When something upset him, he couldn’t control ... use it. He would throw rocks at my other children and say he was going ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... Research and Markets has announced the ... to 2022" report to their offering. ... patients with kidney failure, it replaces the function of kidneys ... blood and thus the treatment helps to keep the patient ... Increasing number of ESRD patients & substantial ...
(Date:6/23/2016)... , June 23, 2016 ... "Pharmaceutical Excipients Market by Type (Organic Chemical (Sugar, ... Formulation (Oral, Topical, Coating, Parenteral) - Global Forecast to ... The global pharmaceutical excipients market ... at a CAGR of 6.1% in the forecast period ...
(Date:6/23/2016)... 23, 2016 Roche (SIX: RO, ROG; OTCQX: ... its Elecsys BRAHMS PCT (procalcitonin) assay as a dedicated ... shock. With this clearance, Roche is the first IVD ... solution for sepsis risk assessment and management. ... and PCT levels in blood can aid clinicians in ...
Breaking Medicine Technology: