"In particular, when beta-amyloid (a hallmark of pathologic Alzheimer's disease) accumulates in the brain, an inflammatory response is likely evoked that produces nitric oxide radicals and downstream neurodegenerative effects. Vitamin E is a powerful fat-soluble antioxidant that may help to inhibit the pathogenesis of dementia," the authors added.
The researchers concluded that further studies are needed to evaluate the possible benefits of dietary intake of antioxidants.
Dr. Michael Holick, a professor of medicine, physiology and biophysics and director of the General Clinical Research Center at Boston University Medical Center said that "these finding are consistent with what we have been believing for a long time, that the brain has receptors for vitamin D, so to maximize brain function you probably need adequate vitamin D."
Holick also believes that vitamin E is probably important for brain health. "It may be that vitamin E improves the health of the brain cell," he said.
For more information on vitamin D, visit the U.S. National Institutes of Health.
SOURCES: Andrew Grey, M.D., associate professor of medicine, University of Auckland, Auckland, New Zealand; Marian Evatt, M.D., assistant professor of neurology, Emory University, Atlanta; Michael Holick, Ph.D., M.D., professor of medicine, physiology and biophysics and director of the General Clinical Research Center at Boston University Medical Center; July 12, 2010, Archives of Internal Medicine; July 2010, Archives of Neurology
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