Navigation Links
Vitamins C, E Won't Cut Risk of Pregnancy-Linked Hypertension
Date:4/7/2010

Large study casts doubt on theory that antioxidant nutrients might help prevent preeclampsia

WEDNESDAY, April 7 (HealthDay News) -- Mothers-to-be who take vitamin C and E supplements do not reduce their risk of the dangerous high blood pressure condition called preeclampsia, a new study finds.

Although other studies have suggested that these antioxidant vitamins could prevent preeclampsia, this trial of more than 10,000 women found there was no sign "that the drugs did anything to prevent the diagnosis of preeclampsia," lead researcher Dr. James M. Roberts, from the departments of obstetrics and gynecology at the University of Pittsburgh, said during an afternoon news conference Tuesday.

"That was the disappointing news," he added. "On the other hand, there was no evidence of problems associated with it [the vitamins] that might have been suspected from earlier trials, except for the interesting finding" that women who took the vitamins experienced spikes in blood pressure slightly more often than women who did not.

The report is published in the April 8 issue of the New England Journal of Medicine.

Preeclampsia is a sudden increase in blood pressure occurring usually after the 20th week of pregnancy. It can affect the mother's kidney, liver and brain and if untreated can be fatal to the mother and the baby or lead to long-term health problems, according to the U.S. National Institutes of Health.

Earlier studies had suggested that antioxidant vitamins C and E might lower the risk of preeclampsia by preventing damage from free radicals, which are byproducts of the body's use of oxygen. The theory was that free radicals prevent the placenta from developing normally and interfere with blood flow from mother to baby.

To test whether there were benefits to taking antioxidants during pregnancy, Roberts's team randomly assigned more than 10,000 women to daily supplements of vitamin C and E, or a placebo, between the 9th and 16th weeks of pregnancy. All the women in the study were having their first child.

In addition, all the women were healthy. None had high blood pressure, kidney disease or gestational diabetes, the researchers noted.

The team found that both groups of women had similar incidence of pregnancy-associated hypertension, seizure, protein in the urine, preeclampsia, blood or liver abnormalities, loss of the fetus, underweight newborns and preterm delivery. These problems occurred in 6.1 percent of women taking vitamin supplements and in 5.7 percent of women receiving a placebo.

Among women taking the vitamins, 7.2 percent developed preeclampsia, compared with 6.7 percent of the women receiving placebo, the researchers noted. This difference was not statistically significant, they added.

According to the NIH, about 6 percent to 8 percent of pregnancies in the United States cause high blood pressure problems. Of these, 70 percent occur in women having their first baby.

Dr. Eva K. Pressman, a professor of obstetrics and gynecology at the University of Rochester Medical Center in New York, said that, "despite our earlier information that oxidative stress played a role in preeclampsia and that we can reduce oxidative stress with vitamins C and E, it doesn't actually seem to work in clinical practice."

These findings don't mean that vitamins C and E are without value, Pressman added. "Vitamin C and E are good for you, but there is no need to take extra doses during pregnancy to prevent preeclampsia."

Pressman noted that for healthy women, right now there is "not much that can be done to prevent preeclampsia."

More information

For more information on preeclampsia, visit the U.S. National Institutes of Health.



SOURCES: Eva K. Pressman, M.D., professor, obstetrics and gynecology, University of Rochester Medical Center, NY; April 6, 2010, teleconference with James M. Roberts, M.D., departments of obstetrics and gynecology, University of Pittsburgh; April 8, 2010, New England Journal of Medicine


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. DR Vitamins, LLC Introduces Vision Clarity Carnosine Eye Drops to Treat Cataracts, Glaucoma, Dry Eye, or Other Eye Ailments
2. VitaminSpice Elects Bill Fields to the Board of Directors
3. VitaminSpice Signs Agreement With Former CEO of Wal-Mart Stores Division for US Distribution
4. All Alternative Medicine Products LLC. Presents a New Line of Natural Nutritional Supplements and Vitamins
5. Update on vitamins and diabetic retinopathy; ethnic norms for preschoolers eyesight
6. eVitamins Launches New Health Encyclopedia
7. New Multivitamins Target Concern Over China's Quality Problems
8. Vitamins stored in bathrooms, kitchens may become less effective
9. MyCareTeam™ Significantly Extends Diabetes Offering to Include Management of Hypertension, Obesity, and Congestive Heart Failure
10. PharmaSmart International, Inc and AstraZeneca Canada Enter Into Strategic Partnership to Elevate Pharmacy Based Hypertension Management
11. Hypertension linked to dementia in older women
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... October 13, 2017 , ... Dickinson ... offers insurance and financial preparation services, is providing an update on a charitable ... , Rock City Rescue is a locally recognized nonprofit that provides shelter and ...
(Date:10/13/2017)... Nevada (PRWEB) , ... October 13, 2017 , ... ... Hemp CBD Oil utilizing Purzorb™ technology. Applying the Purzorb™process to full spectrum CBD oil ... required and providing a CBD form that can be easily incorporated into liquid products, ...
(Date:10/13/2017)... , ... October 13, 2017 , ... The Visiting Nurse ... Market. Featuring a collection of specialty vendors and unique items from across the nation, ... quality-focused health and wellness services offered by the VNA. The boutique will be ...
(Date:10/13/2017)... ... October 13, 2017 , ... Coveros, a leader in agile ... a contract by the Center for Medicare and Medicaid Services (CMS). The Enterprise ... use of Agile methodologies in a consistent and high value manner across CMS ...
(Date:10/12/2017)... ... October 12, 2017 , ... Planet Fitness, one of the largest and fastest ... to open a flagship location in Covington, LA at 401 N. U.S. Highway 190, ... next to Office Depot in the Holiday Square shopping center. Its location allows it ...
Breaking Medicine News(10 mins):
(Date:10/10/2017)... , Oct. 10, 2017   West Pharmaceutical Services, ... solutions for injectable drug administration, today shared the results ... Adapter for improving the intradermal administration of polio vaccines. ... Vaccination Summit in May 2017 by Dr. Ondrej ... Department, World Health Organization (WHO), and recently published in ...
(Date:10/4/2017)... , Oct. 4, 2017 ... single-use, self-contained, illuminating medical devices, today announced regulatory ... Health Surveillance Agency (or Agência Nacional de Vigilância ... first single-use, cordless surgical retractor with integrated LED ... optimal access, illumination and exposure of a tissue ...
(Date:10/2/2017)... The Rebound mobile app is poised to become a vital ... prescription drug addiction. The app empowers users to develop an ... their dosage in a safe, controlled manner while maximizing well-being. ... 100,000 people to sign up will enjoy 3 months of ... ...
Breaking Medicine Technology: