Navigation Links
Vitamin Holds Promise for Alzheimer's Disease
Date:11/5/2008

Treatment cured memory problems in mice, researchers found

WEDNESDAY, Nov. 5 (HealthDay News) -- Researchers report that huge doses of an ordinary vitamin appeared to eliminate memory problems in mice with the rodent equivalent of Alzheimer's disease.

At the moment, there's no way to know if the treatment will have the same effect in humans. Researchers are beginning to enroll Alzheimer's patients in a new study, and scientists aren't ready to recommend that people try the vitamin on their own outside of normal doses.

Still, "it's definitely promising, and if we combine this with other things already out there, we'd probably see a large effect," said study author Kim Green, a researcher at the University of California at Irvine.

Alzheimer's disease affects an estimated 5.2 million Americans, causing senility and often leading to death. The Alzheimer's Association estimates that the disease will strike one in eight Baby Boomers.

There's no cure for the neurodegenerative condition, and medications have only limited effects.

In the new study, Green and colleagues looked at nicotinamide, a form of Vitamin B3 that is found in foods such as pork, peanuts, turkey, chicken, veal, fish, salmon, swordfish, tuna and sunflower seeds.

Previous research has suggested that vitamins such as Vitamin E, Vitamin C and Vitamin B12 may help people lower their risk of developing Alzheimer's disease, said Dr. Ralph Nixon, vice chair of the Alzheimer's Association Medical & Scientific Advisory Council.

In the new study, researchers genetically engineered mice to develop the equivalent of human Alzheimer's disease. They tested their memory by putting them in a shallow pool of water and seeing if they could remember the location of a platform that would allow them to emerge from the water.

The researchers then gave Vitamin B3 to some of the mice; the amount was equal to about 2 grams to 3 grams of the vitamin for humans, Green said. The mice were again tested in the pool.

The findings were published online Nov. 5 in The Journal of Neuroscience.

The forgetful mice who took the vitamin did well. "Cognitively, they were cured," Green said. "They performed as if they'd never developed the disease."

The vitamin appears to work by clearing "tangles" of a protein known as tau in brain cells. In Alzheimer's disease, the protein becomes poisonous and contributes to dangerous clogging inside brain cells.

The vitamin holds promise for people, because it's cheap -- Green bought a year's supply for $30 -- and appears to be safe. Even so, "until we've done the proper clinical trials, I wouldn't advocate people rush out and eat grams of this stuff each day," he said.

Nixon said the new study is "intriguing," but people should be cautious and not assume that "more is better" when it comes to possible treatments, even ones that appear to be safe.

More information

Learn more about Alzheimer's from the Alzheimer's Association.



SOURCES: Kim Green, Ph.D., researcher, University of California at Irvine; Ralph Nixon, M.D., Ph.D., vice chair, Alzheimer's Association Medical & Scientific Advisory Council, and professor, psychiatry and cell biology, New York University School of Medicine; Nov. 5, 2008, The Journal of Neuroscience, online


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Study shines more light on benefit of vitamin D in fighting cancer
2. Vitamin Es lack of heart benefit linked to dosage
3. Fat transforms vitamin C from good cop into bad cop
4. Vitamin C Plus Fat Might Spur Cancer
5. How vitamin C stops the big C
6. Vitamin D Supplements May Lengthen Life
7. Joint Juice Launches New Ready-to-Drink Glucosamine & Vitamin-Enhanced Dietary Supplement Water Nationwide
8. Vitamin Relief Brings Needed Nutrition to School District Resurrecting After Katrina
9. Excessive Multivitamin Use May Raise Risk for Prostate Cancer, from Harvard Mens Health Watch
10. As Winter Approaches, Risk for Vitamin D Deficiency Increases
11. Vitamin D Wont Help Prevent Most Cancers
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Vitamin Holds Promise for Alzheimer's Disease
(Date:3/24/2017)... ... 2017 , ... Judy Buchanan, co-owner of Serenity Natural Health ... says, “I am passionate about sharing Reiki as a holistic, complementary therapy with ... time.” , A Certified Medical Reiki™ Master trained by Raven Keys Medical Reiki™ ...
(Date:3/24/2017)... ... ... “End Time GPS”: a dauntless and enlightened study of the second-coming of Christ, ... of published author, Wesley Gerboth, a World War II veteran, with a highly-regarded reputation ... age ninety-one, he shares the Wisdom God bestowed upon him in this publication. ...
(Date:3/24/2017)... ... March 24, 2017 , ... ... stories about real people of God in congregations across the United States. ... Presbyterian minister ordained in 1964 who has served congregations in seven states throughout ...
(Date:3/23/2017)... Greensboro, NC & Seattle, WA (PRWEB) , ... March 23, 2017 ... ... international public health emergency and now estimates that there could be four million Zika-related ... fastest growing epidemics to date with numbers of US cases reported per year skyrocketing ...
(Date:3/23/2017)... ... March 23, 2017 , ... The physicians of KSF ... the greater Houston Area. The new location is located at 2255 E. Mossy Oaks ... Springwoods Village. This newest location will provide patients living in the north Houston area ...
Breaking Medicine News(10 mins):
(Date:3/24/2017)... Research and Markets has announced the addition of the ... 2022" report to their offering. ... The global wound care market was worth $24,482.9 million in ... during 2016-2022 Among the various wound care products type, the ... market in 2015. Among the various applications, surgical wound segment held the ...
(Date:3/24/2017)... Research and Markets has announced the addition of the "Dental ... ... markets for Dental Implants in US$ Million. The report provides separate comprehensive ... , Europe , Asia-Pacific , ... Annual estimates and forecasts are provided for the period 2015 through ...
(Date:3/24/2017)... 24, 2017 ShangPharma, a leading ... cost-effective drug development and discovery services, technology, ... industry, announced today the intent for a ... be consolidating the Contract Research Organizations (CRO) ... ChemPartner. These entities include ChemPartner Shanghai, ChemPartner ...
Breaking Medicine Technology: