Navigation Links
Vitamin Holds Promise for Alzheimer's Disease
Date:11/5/2008

Treatment cured memory problems in mice, researchers found

WEDNESDAY, Nov. 5 (HealthDay News) -- Researchers report that huge doses of an ordinary vitamin appeared to eliminate memory problems in mice with the rodent equivalent of Alzheimer's disease.

At the moment, there's no way to know if the treatment will have the same effect in humans. Researchers are beginning to enroll Alzheimer's patients in a new study, and scientists aren't ready to recommend that people try the vitamin on their own outside of normal doses.

Still, "it's definitely promising, and if we combine this with other things already out there, we'd probably see a large effect," said study author Kim Green, a researcher at the University of California at Irvine.

Alzheimer's disease affects an estimated 5.2 million Americans, causing senility and often leading to death. The Alzheimer's Association estimates that the disease will strike one in eight Baby Boomers.

There's no cure for the neurodegenerative condition, and medications have only limited effects.

In the new study, Green and colleagues looked at nicotinamide, a form of Vitamin B3 that is found in foods such as pork, peanuts, turkey, chicken, veal, fish, salmon, swordfish, tuna and sunflower seeds.

Previous research has suggested that vitamins such as Vitamin E, Vitamin C and Vitamin B12 may help people lower their risk of developing Alzheimer's disease, said Dr. Ralph Nixon, vice chair of the Alzheimer's Association Medical & Scientific Advisory Council.

In the new study, researchers genetically engineered mice to develop the equivalent of human Alzheimer's disease. They tested their memory by putting them in a shallow pool of water and seeing if they could remember the location of a platform that would allow them to emerge from the water.

The researchers then gave Vitamin B3 to some of the mice; the amount was equal to about 2 grams to 3 grams of the vitamin for humans, Green said. The mice were again tested in the pool.

The findings were published online Nov. 5 in The Journal of Neuroscience.

The forgetful mice who took the vitamin did well. "Cognitively, they were cured," Green said. "They performed as if they'd never developed the disease."

The vitamin appears to work by clearing "tangles" of a protein known as tau in brain cells. In Alzheimer's disease, the protein becomes poisonous and contributes to dangerous clogging inside brain cells.

The vitamin holds promise for people, because it's cheap -- Green bought a year's supply for $30 -- and appears to be safe. Even so, "until we've done the proper clinical trials, I wouldn't advocate people rush out and eat grams of this stuff each day," he said.

Nixon said the new study is "intriguing," but people should be cautious and not assume that "more is better" when it comes to possible treatments, even ones that appear to be safe.

More information

Learn more about Alzheimer's from the Alzheimer's Association.



SOURCES: Kim Green, Ph.D., researcher, University of California at Irvine; Ralph Nixon, M.D., Ph.D., vice chair, Alzheimer's Association Medical & Scientific Advisory Council, and professor, psychiatry and cell biology, New York University School of Medicine; Nov. 5, 2008, The Journal of Neuroscience, online


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Study shines more light on benefit of vitamin D in fighting cancer
2. Vitamin Es lack of heart benefit linked to dosage
3. Fat transforms vitamin C from good cop into bad cop
4. Vitamin C Plus Fat Might Spur Cancer
5. How vitamin C stops the big C
6. Vitamin D Supplements May Lengthen Life
7. Joint Juice Launches New Ready-to-Drink Glucosamine & Vitamin-Enhanced Dietary Supplement Water Nationwide
8. Vitamin Relief Brings Needed Nutrition to School District Resurrecting After Katrina
9. Excessive Multivitamin Use May Raise Risk for Prostate Cancer, from Harvard Mens Health Watch
10. As Winter Approaches, Risk for Vitamin D Deficiency Increases
11. Vitamin D Wont Help Prevent Most Cancers
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Vitamin Holds Promise for Alzheimer's Disease
(Date:5/31/2016)... Beach, Florida (PRWEB) , ... May 31, 2016 ... ... to Jay Butch of CertainTeed Corporation, he knew it was something that contractors ... as state-of-the-art and cutting-edge as it gets,” says Butch, CertainTeed’s Director of Contractor ...
(Date:5/31/2016)... Newport Beach, Calif. (PRWEB) , ... May 31, 2016 , ... ... trust among colleagues, clients, and the industry as a whole. On June 2, Northbound ... Coast Symposium on Addictive Disorders (WCSAD) and presenting the opening plenary on “Leadership: The ...
(Date:5/31/2016)... ... ... WaterField Designs, an innovative leader in custom laptop sleeve s, ... Kit , the ideal gift upgrade for Dad this Father’s Day . Made ... designed for Dad’s grooming routine. Two compartments keep items separated and organized. A leather ...
(Date:5/31/2016)... ... 31, 2016 , ... Interest is on the rise for using the CRISPR-Cas9 ... tool for RNAi hit validation. A key reason may be that high-throughput synthesis—combined with ... CRISPR RNA (crRNA) collections in arrayed formats. , Arrayed crRNA screens ...
(Date:5/31/2016)... ... May 31, 2016 , ... MinerEye today announced ... Security Infrastructure Protection report by Gartner1 Inc. , Each year, Gartner identifies new ... evaluating these innovative vendors and their products and services. , According to Gartner, ...
Breaking Medicine News(10 mins):
(Date:5/27/2016)... , May 27, 2016 According ... of hypertension is driving ambulatory blood pressure monitoring system ... elasticity and their ability to respond to different pressure ... condition can lead to various cardiovascular disorders such as ... disease. These diseases are growing in prevalence each year. ...
(Date:5/26/2016)... , May 26, 2016 According ... "Medical Waste Management Market - U.S. Industry Analysis, Size, Share, ... management market in the U.S. was valued at US$ 5.89 ... CAGR of 3.4% from 2015 to 2023 to reach US$ ... analysis of current and emerging needle free drug delivery devices ...
(Date:5/25/2016)... FDA 510(k) clearance covers ... for urological and surgical applications Mauna ... Cellvizio®, the multidisciplinary confocal laser endomicroscopy (CLE) platform, ... US with the 12 th 510(k) clearance ... This new FDA clearance covers Confocal Miniprobes indicated ...
Breaking Medicine Technology: