Navigation Links
Vitamin D Use Linked to Lower Mortality in Kidney Patients
Date:5/16/2008

Study finds chronic disease sufferers gain benefit from calcitriol, an oral form

FRIDAY, May 16 (HealthDay News) -- Taking activated vitamin D may cut the risk of death for people with moderate to severe chronic kidney disease by about one quarter, a new study suggests.

During a two-year study of more than 1,400 patients, those being treated with calcitriol, an oral form of activated vitamin D, had their overall risk of death lowered by 26 percent when compared with those not on the drug. Those taking calcitriol were also less likely to develop end-stage renal disease, which requires dialysis to replace lost kidney function.

Patients with advanced chronic kidney disease (CKD) often take calcitriol to treat elevated levels of parathyroid hormone (hyperparathyroidism), a condition that can weaken the bones.

"Although activated vitamin D is known to influence many biological processes, previous clinical knowledge is limited to its effect on parathyroid hormone levels," study co-author Dr. Bryan Kestenbaum, of the University of Washington in Seattle, said in a prepared statement.

Overall, calcitriol use was linked to a 20 percent reduction in the likelihood of either dying or needing dialysis. The reduction in mortality with calcitriol appeared to be unrelated to its effect on parathyroid hormone levels.

The study is published in the August issue of the Journal of the American Society of Nephrology.

The lack of data on other factors that may have improved survival rates in patients taking calcitriol does limit the study's conclusions, as does the narrow range of demographics among its subjects, the study added. Those studied were primarily older, white men, so the results are not guaranteed to repeat when treatment is given to a younger, more ethnically diverse population with chronic kidney disease (CKD).

"Randomized clinical trials are needed to test the hypothesis that vitamin D therapy can improve cardiovascular health and survival in CKD," Kestenbaum said. "Future studies should also examine the role of non-activated vitamin D, which is less expensive and less toxic."

More information

The U.S. National Library of Medicine has more about the causes and treatment of kidney failure.



-- Kevin McKeever



SOURCE: American Society of Nephrology, news release, May 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Study shines more light on benefit of vitamin D in fighting cancer
2. Vitamin Es lack of heart benefit linked to dosage
3. Fat transforms vitamin C from good cop into bad cop
4. Vitamin C Plus Fat Might Spur Cancer
5. How vitamin C stops the big C
6. Vitamin D Supplements May Lengthen Life
7. Joint Juice Launches New Ready-to-Drink Glucosamine & Vitamin-Enhanced Dietary Supplement Water Nationwide
8. Vitamin Relief Brings Needed Nutrition to School District Resurrecting After Katrina
9. Excessive Multivitamin Use May Raise Risk for Prostate Cancer, from Harvard Mens Health Watch
10. As Winter Approaches, Risk for Vitamin D Deficiency Increases
11. Vitamin D Wont Help Prevent Most Cancers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/24/2016)... , ... June 24, 2016 , ... Marcy was in a crisis. Her son James, ... out at his family verbally and physically. , “When something upset him, he couldn’t control ... use it. He would throw rocks at my other children and say he was going ...
(Date:6/24/2016)... ... June 24, 2016 , ... Dr. Amanda Cheng, ... treatment. Dr. Cheng has extensive experience with all areas of orthodontics, including robotic ... osteogenic orthodontics. , Micro-osteoperforation is a revolutionary adjunct to orthodontic treatment. It ...
(Date:6/24/2016)... ... 24, 2016 , ... People across the U.S. are sharpening their pencils and ... essay contest in which patients and their families pay tribute to a genetic counselor ... National Society of Genetic Counselors (NSGC) Annual Education Conference (AEC) this September. , ...
(Date:6/24/2016)... , ... June 24, 2016 , ... ... The Grove Investment Group (TGIG), has initiated cultivation and processing operations at its ... Vegas and Pahrump, Nevada. , Puradigm is the manufacturer of a complete system ...
(Date:6/24/2016)... D.C. (PRWEB) , ... June 24, 2016 , ... ... Heroes Golf Classic Tournament held on June 20th at the Woodmont Country Club ... charity, Luke’s Wings, an organization dedicated to helping service members that have been wounded ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... Dehaier Medical Systems Ltd. (NASDAQ: ... and sells medical devices and wearable sleep respiratory products ... cooperation agreement with Hongyuan Supply Chain Management Co., Ltd. ... 20, 2016, to develop Dehaier,s new Internet medical technology ... will leverage Hongyuan Supply Chain,s sales platform to reach ...
(Date:6/24/2016)... India , June 24, 2016 ... Needles Market by Type (Standard Pen Needles, Safety Pen ... Therapy (Insulin, GLP-1, Growth Hormone), Mode of Purchase (Retail, ... by MarketsandMarkets, This report studies the market for the ... expected to reach USD 2.81 Billion by 2021 from ...
(Date:6/24/2016)... June 24, 2016  Arkis BioSciences, a leading ... and more durable cerebrospinal fluid treatments, today announced ... Series-A funding is led by Innova Memphis, followed ... other private investors.  Arkis, new financing will accelerate ... the market release of its in-licensed Endexo® technology. ...
Breaking Medicine Technology: