Navigation Links
Vitamin D Use Linked to Lower Mortality in Kidney Patients
Date:5/16/2008

Study finds chronic disease sufferers gain benefit from calcitriol, an oral form

FRIDAY, May 16 (HealthDay News) -- Taking activated vitamin D may cut the risk of death for people with moderate to severe chronic kidney disease by about one quarter, a new study suggests.

During a two-year study of more than 1,400 patients, those being treated with calcitriol, an oral form of activated vitamin D, had their overall risk of death lowered by 26 percent when compared with those not on the drug. Those taking calcitriol were also less likely to develop end-stage renal disease, which requires dialysis to replace lost kidney function.

Patients with advanced chronic kidney disease (CKD) often take calcitriol to treat elevated levels of parathyroid hormone (hyperparathyroidism), a condition that can weaken the bones.

"Although activated vitamin D is known to influence many biological processes, previous clinical knowledge is limited to its effect on parathyroid hormone levels," study co-author Dr. Bryan Kestenbaum, of the University of Washington in Seattle, said in a prepared statement.

Overall, calcitriol use was linked to a 20 percent reduction in the likelihood of either dying or needing dialysis. The reduction in mortality with calcitriol appeared to be unrelated to its effect on parathyroid hormone levels.

The study is published in the August issue of the Journal of the American Society of Nephrology.

The lack of data on other factors that may have improved survival rates in patients taking calcitriol does limit the study's conclusions, as does the narrow range of demographics among its subjects, the study added. Those studied were primarily older, white men, so the results are not guaranteed to repeat when treatment is given to a younger, more ethnically diverse population with chronic kidney disease (CKD).

"Randomized clinical trials are needed to test the hypothesis that vitamin D therapy can improve cardiovascular health and survival in CKD," Kestenbaum said. "Future studies should also examine the role of non-activated vitamin D, which is less expensive and less toxic."

More information

The U.S. National Library of Medicine has more about the causes and treatment of kidney failure.



-- Kevin McKeever



SOURCE: American Society of Nephrology, news release, May 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Study shines more light on benefit of vitamin D in fighting cancer
2. Vitamin Es lack of heart benefit linked to dosage
3. Fat transforms vitamin C from good cop into bad cop
4. Vitamin C Plus Fat Might Spur Cancer
5. How vitamin C stops the big C
6. Vitamin D Supplements May Lengthen Life
7. Joint Juice Launches New Ready-to-Drink Glucosamine & Vitamin-Enhanced Dietary Supplement Water Nationwide
8. Vitamin Relief Brings Needed Nutrition to School District Resurrecting After Katrina
9. Excessive Multivitamin Use May Raise Risk for Prostate Cancer, from Harvard Mens Health Watch
10. As Winter Approaches, Risk for Vitamin D Deficiency Increases
11. Vitamin D Wont Help Prevent Most Cancers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/18/2017)... ... February 17, 2017 , ... ... Devicemakers , Sponsored by Axendia, **FDAnews Free Webinar**, March 1, 2017 — ... looking to reduce their regulatory burden? Pay dividends in enhanced and predictable ...
(Date:2/18/2017)... California (PRWEB) , ... February 17, 2017 , ... ... info@drvallecillos.com , drvallecillos.com , Beverly Hills plastic surgeon Dr. Glenn ... fat cells. , Dr. Vallecillos says, "Traditionally, plastic surgery has been centered around ...
(Date:2/18/2017)... ... February 18, 2017 , ... A new directory from the ... to easily connect elderly veterans of America's armed forces to a range of ... conveys material on this year's increase in the Veterans Pension with Aid & ...
(Date:2/17/2017)... ... February 17, 2017 , ... The Alliance Healthcare ... designed to further positively impact the health and wellness of our community in ... it our duty to seriously consider releasing our assets beyond our 5% targeted ...
(Date:2/17/2017)... , ... February 17, 2017 ... ... Approval and Reimbursement , **An FDAnews Webinar**, Feb. 22, 2017 — 1:30 ... the critical reimbursement questions manufacturers should be asking before selecting an FDA ...
Breaking Medicine News(10 mins):
(Date:2/17/2017)... Cryoablation, Electrical, Endometrial Hydrothermal, Laser/Light, Microwave, Radiofrequency, Ultrasound, Cardiovascular, ... is expected to grow at a CAGR of 9.4% from 2017-2022 ... grow at a CAGR of 9.5% from 2017 to 2027. The ... ... will benefit you Read on to discover how you can ...
(Date:2/17/2017)... , Feb. 17, 2017 Arvinas LLC, ... drugs based on protein degradation, today announced the presentation ... (AR) PROTAC during a poster session at the American ... GU) in Orlando, FL. ... validate our platform and the potential of PROTACs to ...
(Date:2/17/2017)... , Feb 17, 2017 Research and Markets has ... Business Report" report to their offering. ... The report provides separate comprehensive analytics for the US, ... , Asia-Pacific , and Rest of World. Annual ... a six-year historic analysis is provided for these markets. Market data and ...
Breaking Medicine Technology: