Navigation Links
Vitamin D No Magic Bullet for Osteoarthritis

By Steven Reinberg
HealthDay Reporter

SUNDAY, Nov. 7 (HealthDay News) -- People suffering from osteoarthritis of the knee appear to receive no relief from taking vitamin D supplements, U.S. researchers report.

"I've never heard of vitamin D as an intervention strategy," said Dr. Kevin Dalal, an assistant professor of rehabilitation medicine at the University of Miami Miller School of Medicine. "I am not surprised it didn't work. It's a tough process to try to change after it's been going on for years."

He noted that 25 million Americans suffer from osteoarthritis.

"The joints that bear the weight take the brunt of the disease. The joint space starts narrowing, bone spurs develop and the joint becomes very uncomfortable," explained Dalal, who was not involved in the study.

He said the theory behind why vitamin D might work is its ability to increase the absorption of calcium, which might strengthen the knee joint.

The findings were to be presented Sunday at the American College of Rheumatology's annual meeting in Atlanta.

To see if vitamin D might have a beneficial effect, a team led by Dr. Timothy McAlindon, an associate professor of medicine in the division of rheumatology at Tufts New England Medical Center, studied 146 people with osteoarthritis of the knee.

The participants were randomly assigned to take vitamin D or placebo. Those taking vitamin D group started taking 2,000 International Units (IU) daily.

Over the course of the study, doses of vitamin D were increased in 2,000 IU increments to maintain a blood level of the vitamin at more than 30 nanograms per milliliter, the researchers noted.

In addition, McAlindon's team gave the participants physical function tests and X-rayed the affected knee at the start of the study and one year later. They also had the participants undergo an MRI at the start and at the end of the study.

These data helped the researchers keep track of knee cartilage volume and thickness, along with bone marrow lesion volume, to see if there were any changes over time.

After two years, there were no substantial differences between those people taking vitamin D and those taking placebo, the researchers found.

"This study tested whether vitamin D supplementation, given over a two-year period, could influence the rate of progression of joint damage in people with knee osteoarthritis," McAlindon said in a statement. "The study found no difference compared to a placebo treatment."

Osteoarthritis is the most common joint disease affecting middle-age and older people. The condition causes progressive damage to the joint cartilage and causes changes in the structures around the joint, the researchers said.

These changes can include accumulation of fluid, bony overgrowth, and loosening and weakness of muscles and tendons, all of which can limit movement and cause pain and swelling.

Dalal noted that the only treatment for osteoarthritis is physical therapy, exercise and anti-inflammatory medication. Eventually, many people suffering from knee osteoarthritis will need a joint replacement, he said.

Research suggests that other treatments such as glucosamine and other herbal remedies also don't work, Dalal said. "But some people are desperate and try alternatives," he said.

More information

For more information on osteoarthritis, visit the U.S. National Library of Medicine.

SOURCES: Kevin Dalal, M.D., assistant professor, rehabilitation medicine, University of Miami Miller School of Medicine; Nov. 7, 2010, presentation, American College of Rheumatology annual meeting, Atlanta

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. eVitamins Launches New Health Encyclopedia
2. New Multivitamins Target Concern Over China's Quality Problems
3. Vitamin B3 May Help Repair Brain After a Stroke
4. Vitamins stored in bathrooms, kitchens may become less effective
5. Vitamin Shoppe, Inc. To Present at the 2010 Stifel Nicolaus Consumer Conference
6. Vitamin D lifts mood during cold weather months
7. Henry Ford Hospital study shows link between vitamin D, skin cancer
8. Metabolife's New Green Tea + Vitamin D3 Helps Promote Bone Health and Supports Weight Management
9. Boosting Vitamin D Can Do a Heart Good
10. Study: Low Levels of Vitamin D Linked to Higher Rates of Asthma in African American Kids
11. Too Many Infants Short on Vitamin D
Post Your Comments:
Related Image:
Vitamin D No Magic Bullet for Osteoarthritis
(Date:11/27/2015)... ... November 27, 2015 , ... According to an ... changing the way that they are handling security in light of the recent terrorist ... presence in an attempt to stop an attack from reaching U.S. soil. Especially around ...
(Date:11/27/2015)... ... November 27, 2015 , ... A team of Swiss doctors has released ... Surviving Mesothelioma has just posted the findings on the website. Click here to ... cases of 136 mesothelioma patients who were treated with chemotherapy followed by EPP surgery. ...
(Date:11/27/2015)... (PRWEB) , ... November 27, 2015 , ... ... filthy the toilets were," said an inventor from Hillside, N.J. "Many people catch ... seat cover so that individuals will always be protected from germs." , He ...
(Date:11/27/2015)... ... November 27, 2015 , ... The ... of USA Today in Atlanta, Dallas, New York, Minneapolis, South Florida, with a ... component is distributed nationally, through a vast social media strategy and across a ...
(Date:11/27/2015)... ANGELES, CA (PRWEB) , ... November 27, 2015 , ... MPWH, the No.1 Herpes-only dating ... of 30 (see Table 1-1 ). More than 3.7 billion people under the ... virus type 1 (HSV-1), according to WHO's first global estimates of HSV-1 infection . ...
Breaking Medicine News(10 mins):
(Date:11/25/2015)... 25, 2015 AAIPharma Services Corp./Cambridge Major ... at least $15.8  Million to expand its laboratories ... . The expansion will provide additional office ... growing demands of the pharmaceutical and biotechnology markets. ... will provide up to 40,000 square feet of ...
(Date:11/25/2015)... 25, 2015  Henry Schein, Inc., the world,s largest ... dental, medical and animal health practitioners, will unveil at ... Henry Schein ConnectDental® Pavilion , which brings together for ... solutions designed to help any practice or laboratory enter ... for a schedule of experts appearing at the Pavilion. ...
(Date:11/25/2015)... , Nov. 25, 2015  Trovagene, Inc. (NASDAQ: ... announced that Chief Executive Officer Antonius Schuh, Ph.D., is ... th Annual Piper Jaffray Healthcare Conference. ... New York Palace Hotel in New York ... p.m. EST. Mr. Schuh will be available for one-on-one ...
Breaking Medicine Technology: