Navigation Links
Vitamin C improves pulmonary function in newborns of pregnant smoking women
Date:5/22/2012

ATS 2012, SAN FRANCISCO Vitamin C supplementation in pregnant women who are unable to quit smoking significantly improves pulmonary function in their newborns, according to a new study.

"Smoking during pregnancy is known to adversely affect the lung development of the developing baby," said Cindy McEvoy, MD, associate professor of pediatrics at Oregon Health & Science University Doernbecher Children's Hospital. "We found that daily use of vitamin C (500 mg/day) by smoking pregnant woman significantly improved pulmonary function tests administered to their offspring at about 48 hours postpartum."

The results will be presented at the ATS 2012 International Conference in San Francisco.

The study enrolled the newborns of 159 smoking women and randomized them to daily vitamin C (500 mg) or placebo before 22 weeks gestation and treatment was continued through delivery.76 non smoking pregnant women were also studied. The primary outcome of the study was the measurement of the newborn's lung function with a pulmonary function test at about 48 hours of life. This assessment included measurement of peak tidal expiratory flow to expiratory time (TPTEF:TE) and respiratory compliance (Crs).

Smokers treated with placebo had significantly lower levels of ascorbic acid than non-smokers, but levels returned to those of non-smokers in smokers randomized to vitamin C. Newborns of smoking women randomized to placebo had decreased TPTEF:TE and Crs compared to non-smokers. Both TPTEF:TE and Crs were significantly increased by vitamin C supplementation, returning them nearly to the levels seen in non-smokers.

"In our pilot study, we were able to show that babies born to smoking pregnant women who were randomized to daily supplemental vitamin C had significantly improved pulmonary/lung function tests compared to babies born to smoking women who were randomized to placebo," said Dr. McEvoy.

"Moreover, although our study numbers were small, we found that one particular genetic variant that has been shown to increase the risk of smokers developing cancer and is associated with both a reduced ability to quit smoking and a high likelihood of relapse, also seemed to intensify the harmful effects of maternal smoking on babies' lungs. Although the lung function of all babies born to smokers in our study was improved by supplemental vitamin C, our preliminary data suggest, importantly, that vitamin C may help those babies at the greatest risk of harm during their development from their mother's smoking in pregnancy."

"Getting women to quit smoking during pregnancy has to be priority one, but this study provides a way to potentially help the infants born to at least 12% of pregnant women who cannot quit smoking when pregnant." said Dr. McEvoy. "Vitamin C supplementation may block some of the in-utero effects of smoking on fetal lung development."

"Our findings are important because improved lung function tests at birth are associated with less wheezing and asthma in childhood," concluded Dr. McEvoy. "Vitamin C is a simple, safe, and inexpensive treatment that may decrease the impact of smoking during pregnancy on the respiratory health of children."


'/>"/>

Contact: Nathaniel Dunford
ndunford@thoracic.org
212-315-8620
American Thoracic Society
Source:Eurekalert

Related medicine news :

1. eVitamins Launches New Health Encyclopedia
2. New Multivitamins Target Concern Over China's Quality Problems
3. Vitamin B3 May Help Repair Brain After a Stroke
4. Vitamins stored in bathrooms, kitchens may become less effective
5. Vitamin Shoppe, Inc. To Present at the 2010 Stifel Nicolaus Consumer Conference
6. Vitamin D lifts mood during cold weather months
7. Henry Ford Hospital study shows link between vitamin D, skin cancer
8. Metabolife's New Green Tea + Vitamin D3 Helps Promote Bone Health and Supports Weight Management
9. Boosting Vitamin D Can Do a Heart Good
10. Study: Low Levels of Vitamin D Linked to Higher Rates of Asthma in African American Kids
11. Too Many Infants Short on Vitamin D
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... October 13, 2017 , ... Yisrayl Hawkins, Pastor and ... explains one of the most popular and least understood books in the Holy Scriptures, ... puzzling descriptions that have baffled scholars for centuries. Many have tossed it off as ...
(Date:10/13/2017)... ... October 13, 2017 , ... “The Journey: From the Mountains to ... to save lost souls in the Philippines. “The Journey: From the Mountains to the ... teacher of the Bible. She has taught all ages and currently teaches a class ...
(Date:10/12/2017)... ... October 12, 2017 , ... CitiDent ... sleep apnea using cutting-edge Oventus O2Vent technology. As many as 18 million ... by frequent cessation in breathing. Oral appliances can offer significant relief to about ...
(Date:10/12/2017)... PALM CITY, Fla. (PRWEB) , ... October 12, 2017 , ... ... of cold therapy products, announced today the introduction of an innovative new design of ... the multipurpose pad so you get maximum comfort while controlling your pain while using ...
(Date:10/12/2017)... ... 2017 , ... Information about the technology: , Otomagnetics has ... prevention of a major side effect of chemotherapy in children. Cisplatin and carboplatin ... cisplatin, hearing loss is FDA listed on-label as a dose limiting toxicity. Hearing ...
Breaking Medicine News(10 mins):
(Date:10/4/2017)... LAWRENCE, Mass. , Oct. 4, 2017 /PRNewswire/ ... developer of single-use, self-contained, illuminating medical devices, today ... National Health Surveillance Agency (or Agência Nacional ... ®. The first single-use, cordless surgical retractor with ... ONETRAC provides optimal access, illumination and exposure of ...
(Date:10/2/2017)... , Oct. 2, 2017 The Rebound mobile ... the struggle to reverse the tide of prescription drug addiction. ... regulating their medicine intake and stepping down their dosage in ... to launch in December 2017; the first 100,000 people to ... more at http://www.rebound-solution.com/ ...
(Date:9/25/2017)... --  Montrium , an industry leader in powerful ... Trial Master Files & Inspection Readiness Conference ( ... Services has selected eTMF Connect to ... a leading European contract research organization (CRO), will ... enable greater collaboration with sponsors, improve compliance and ...
Breaking Medicine Technology: