Navigation Links
Vitamin B3 as a novel approach to treat fungal infections
Date:7/8/2010

This release is available in French.

Montreal, July 8, 2010 - A team of scientists from the Institute for Research in Immunology and Cancer (IRIC) of the University of Montreal have identified vitamin B3 as a potential antifungal treatment. Led by IRIC Principal Investigators Martine Raymond, Alain Verreault and Pierre Thibault, in collaboration with Alaka Mullick, from the Biotechnology Research Institute of the National Research Council Canada, the study is the subject of a recent article in Nature Medicine.

Infections by the yeast Candida albicans represent a significant public health problem and a common complication in immunodeficient individuals such as AIDS patients, cancer patients undergoing chemotherapy and recipients of organ transplants. While some treatments are available, their efficacy can be compromised by the emergence of drug-resistant strains.

The current study shows that a C. albicans enzyme, known as Hst3, is essential to the growth and survival of the yeast. Researchers found that genetic or pharmacological inhibition of Hst3 with nicotinamide, a form of vitamin B3, strongly reduced C. albicans virulence in a mouse model. Both normal and drug-resistant strains of C. albicans were susceptible to nicotinamide. In addition, nicotinamide prevented the growth of other pathogenic Candida species and Aspergillus fumigatus (another human pathogen), thus demonstrating the broad antifungal properties of nicotinamide.

"There is an urgent need to develop new therapies to kill C. albicans because it is one of the leading causes of hospital-acquired infections and is associated with high mortality rates," explains Martine Raymond, who is also a professor at the University of Montreal Department of Biochemistry. "Although many issues remain to be investigated, the results of our study are very exciting and they constitute an i
'/>"/>

Contact: Carolyne Lord
carolyne.lord@umontreal.ca
514-343-7282
University of Montreal
Source:Eurekalert  

Page: 1 2

Related medicine news :

1. eVitamins Launches New Health Encyclopedia
2. New Multivitamins Target Concern Over China's Quality Problems
3. Vitamin B3 May Help Repair Brain After a Stroke
4. Vitamins stored in bathrooms, kitchens may become less effective
5. Vitamin Shoppe, Inc. To Present at the 2010 Stifel Nicolaus Consumer Conference
6. Vitamin D lifts mood during cold weather months
7. Henry Ford Hospital study shows link between vitamin D, skin cancer
8. Metabolife's New Green Tea + Vitamin D3 Helps Promote Bone Health and Supports Weight Management
9. Boosting Vitamin D Can Do a Heart Good
10. Study: Low Levels of Vitamin D Linked to Higher Rates of Asthma in African American Kids
11. Too Many Infants Short on Vitamin D
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Vitamin B3 as a novel approach to treat fungal infections
(Date:8/28/2015)... ... ... For Dallas, the time is nearing for the annual Heart Walk, and ... The American Heart Association hosts their well-known Heart Walk to raise money in awareness ... can be made. Walkers can participate in the cause and someone can also donate, ...
(Date:8/28/2015)... ... August 28, 2015 , ... Loved ones of a ... struggling with chemical dependency, may be able to find some hope in the ... treatment center for addiction located in Western Michigan. Focusing on several different aspects ...
(Date:8/28/2015)... (PRWEB) , ... August 28, 2015 , ... Medical Solutions, ... 2015 Best Places to Work in Healthcare by Modern Healthcare and will ... , Now in its eighth year, the Best Places to Work in Healthcare ...
(Date:8/28/2015)... ... ... The Quatela Center for Plastic Surgery is excited to bring patients the ground ... the Food and Drug Administration to eliminate submental fat, also known as the double ... among the premier cosmetic surgeons in Rochester to offer this innovative procedure.     , Developed ...
(Date:8/28/2015)... , ... August 28, 2015 , ... ... is dedicated to distributing health information technology innovation to transform quality and efficiency ... of the survey will be de-identified and aggregated before being publicly shared to ...
Breaking Medicine News(10 mins):Health News:North Central Surgical Center’s Subsidiary Participates in Walk 2Health News:Best Drug Rehabilitation Releases New Video Outlining Patients' Personal Recovery Stories 2Health News:Best Drug Rehabilitation Releases New Video Outlining Patients' Personal Recovery Stories 3Health News:Medical Solutions Recognized as One of 2015 Best Places to Work in Healthcare 2Health News:Medical Solutions Recognized as One of 2015 Best Places to Work in Healthcare 3Health News:Non-surgical Treatment to Get Rid of The "Double Chin," Kybella™, Now Available at the Quatela Center for Plastic Surgery 2Health News:Non-surgical Treatment to Get Rid of The "Double Chin," Kybella™, Now Available at the Quatela Center for Plastic Surgery 3Health News:WEDI's The Sullivan Institute for Healthcare Innovation Releases Gaps in Care Survey 2
... Nov. 30 Mary Rita Hyland, Assistant Vice President of ... elected to the 2010 Board for the Workgroup for Electronic ... of leadership positions at SSI since joining the organization in ... of the Quality Assurance division and Business Continuity for SSI. ...
... of ,stroke belt, study finds , MONDAY, ... belt" of the southern United States have a lifelong higher ... live elsewhere later, a new study shows. , Data on ... South Carolina, Georgia, Tennessee, Arkansas, Mississippi and Alabama show a ...
... , LOS ANGELES, ... as a woman, and brings with it a host of uncomfortable ... mood swings, weight gain , night sweats and lethargy are ... worse, menopause signs and symptoms can show up a ...
... , ... , NEW YORK, Nov. 30 Distance runners who live at ... races in areas that are at sea level. Can heart failure ... tent-like, high-altitude simulator? , That is the question being studied among 15 heart ...
... Fla., Nov. 30 The launch of Invivo Corporation,s ... FDA-cleared, fully-automated morphological system for the detection and analysis ... system will be officially unveiled at the Radiological Society ... Developed in partnership with leading experts in breast MRI, ...
... safe transplant results in animals , MONDAY, Nov. 30 (HealthDay ... cells from transplanted human-derived umbilical cord blood could help treat ... that such stem cells can differentiate into a long list ... Soon Park of the Samsung Medical Center in Seoul, Korea, ...
Cached Medicine News:Health News:SSI Assistant Vice President Elected to WEDI Board 2Health News:Birth in South Raises Stroke Risk for Life 2Health News:Birth in South Raises Stroke Risk for Life 3Health News:Anti-Aging Institute of California Offers New Natural Solution for Menopause Symptoms 2Health News:Can Exposure to Low Oxygen Levels Benefit Heart Failure Patients? 2Health News:Can Exposure to Low Oxygen Levels Benefit Heart Failure Patients? 3Health News:Can Exposure to Low Oxygen Levels Benefit Heart Failure Patients? 4Health News:New Breast MRI Technology Enables Enhanced Breast Cancer Detection 2Health News:New Breast MRI Technology Enables Enhanced Breast Cancer Detection 3
(Date:8/28/2015)... SOUTH SAN FRANCISCO, Calif. , Aug. 28, 2015 ... therapeutics for the treatment of cancer, today announced the ... the U.S. Securities and Exchange Commission (SEC) relating to ... The number of shares to be offered and the ... determined. CytomX intends to list its common stock under ...
(Date:8/28/2015)... 2015 Research and Markets ... "Investigation Report on China,s Bevacizumab Market ,2010-2019" ... under the trade name of Avastin, bevacizumab injection is ... 2010, it was approved by CFDA to treat metastatic ... China all come from Roche and its ...
(Date:8/28/2015)... 28, 2015  Today, in final recognition of the ... Health Week, 1-800 Contacts is sharing how to keep ... lens wearers who do not properly care for their ... infections. Most contact lens wearers understand ... clean lens case is sometimes overlooked.  When proper steps ...
Breaking Medicine Technology:CytomX Files Registration Statement for Proposed Initial Public Offering 2Investigation Report on China's Bevacizumab Market 2015-2019 21-800 Contacts Shares Tips on How to Clean Lens Cases 2
... Genomic Health, Inc . (Nasdaq: GHDX ... Executive Chairman of the Board, will present at the Piper ... November 29, 2011 at 1:30 p.m. Eastern Time (ET).   ... of the presentation, visit the Investor Relations section of Genomic ...
... Nov. 22, 2011 Frost & Sullivan honors ... Sullivan 2011 North American Technology Innovation Award in ... VoXcell ® Imaging Suite.  For the first ... throughout the enterprise using robust industry-standard applications, leading-edge ...
Cached Medicine Technology:Genomic Health to Present at the Piper Jaffray Health Care Conference 2Genomic Health to Present at the Piper Jaffray Health Care Conference 3KJAYA Medical Honored with 2011 Frost & Sullivan Award for Technology Innovation in Web-based Medical Imaging Data Management 2
Microcontroller-based isolated electrosurgical generator, designed for all general purpose surgical procedures. Unit includes: Instant Response technology, adaptive REM system, isolated output, CEM c...
Maddox rod and occluder...
Long handle occluder - White...
Double Ended Occluders...
Medicine Products: