Navigation Links
Vitamin B12 Key to Aging Brain
Date:9/8/2008

Deficiency led to more brain shrinkage, study shows

MONDAY, Sept. 8 (HealthDay News) -- Older individuals with low levels of vitamin B12 seem to be at increased risk of having brain atrophy or shrinkage, new research suggests.

Brain atrophy is associated with Alzheimer's disease and impaired cognitive function.

Although the study, published in the Sept. 8 issue of Neurology, can't confirm that lower levels of B12 actually cause brain atrophy, they do suggest that "we ought to be more aware of our B12 status, especially people who are vulnerable to B12 deficiency [elderly, vegetarians, pregnant and lactating women, infants], and take steps to maintain it by eating a balanced and varied diet," said study co-author Anna Vogiatzoglou, a registered dietician and doctoral candidate in the department of physiology, anatomy and genetics at the University of Oxford, in England.

"It's worth looking at B12 levels. It's a simple blood test," affirmed Dr. Shari Midoneck, an internist at the Iris Cantor Women's Health Center in New York City. "It doesn't hurt to take B12."

Good sources of the vitamin include meat, fish, milk and fortified cereals.

According to the study authors, vitamin B12 deficiency is a public health problem, especially among older people.

This study involved 107 volunteers aged 61 to 87 who were cognitively normal at the beginning of the study. All participants underwent annual clinical exams, MRI scans and cognitive tests and had blood samples taken.

Individuals with lower vitamin B12 levels at the start of the study had a greater decrease in brain volume. Those with the lowest B12 levels had a sixfold greater rate of brain volume loss compared with those who had the highest levels of the vitamin.

Interestingly, none of the participants were deficient in vitamin B12, they just had low levels within a normal range.

"They all had normal B12 levels, yet there was a difference between the higher levels and the lower levels in terms of brain shrinkage, which is new information which could potentially change what we recommend to people in terms of diet," said Dr. Jonathan Friedman, an associate professor of surgery and neuroscience and experimental therapeutics at Texas A&M Health Science Center College of Medicine and associate dean of the College of Medicine, Bryan-College Station campus.

Other risk factors for brain atrophy include high blood pressure, diabetes and high cholesterol.

Not only might B12 levels be a modifiable risk factor for cognitive decline, it might also be a clue to help clinicians assess cognitive problems earlier on.

Right now, it's not clear what the biological mechanisms behind the link might be, nor is it clear whether added B12 would avert brain atrophy.

"We are doing a clinical trial in Oxford in which we are giving B vitamins [including B12] to elderly people with memory impairment," Vogiatzoglou said. "In this trial, we are doing MRI scans at the start and the end, and so, we will be able to find out if taking B vitamins really does slow down the shrinking of the brain. The trial will be completed in 2009."

More information

Learn more about vitamin B-12 at the National Institutes of Health.



SOURCES: Anna Vogiatzoglou, R.D., doctoral candidate, department of physiology, anatomy and genetics, University of Oxford, England; Jonathan Friedman, M.D., associate professor, surgery and neuroscience and experimental therapeutics, Texas A&M Health Science Center College of Medicine, and associate dean, College of Medicine, Bryan-College Station campus, and director, Texas Brain and Spine Institute, College Station; Shari Midoneck, M.D., associate clinical professor, medicine, Weill Cornell Medical College, and internist, Iris Cantor Women's Health Center, New York City; Sept. 8, 2008, Neurology


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Genetic variants associated with vitamin B12
2. Vitamin B, Folate Supplements Wont Help Heart
3. New Vitamin Targets Needs of Nurses
4. Low Vitamin D Raises Womens Hip Fracture Risk
5. Lack of Vitamin D Boosts Death Risk
6. Vitamin C injections slow tumor growth in mice
7. Vitalize(TM) Receives Top Multivitamin Rating
8. July 2008 Mayo Clinic Womens HealthSource Highlights Vitamin D, Savvy Use of Sunscreen and Gastrointestinal Upset and Celiac Disease
9. Moms Vitamin D Levels Affect Babys Dental Health
10. Mothers vitamin D status during pregnancy will affect her babys dental health
11. Photo: VitaminLife.com Sees Internet Sales Up 40% in Major Metro Markets as Gas Crisis Looms; Shopping Behaviors Change as People Conserve Gas
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Vitamin B12 Key to Aging Brain
(Date:12/7/2016)... , ... December 07, 2016 , ... ... consultation services from offices located in South Lyon, Dewitt, Williamston, East Lansing, Ann ... basketball coach who needs treatment for a brain tumor. , Jason Bauer and ...
(Date:12/7/2016)... ... December 07, 2016 , ... One of two inventors from Glen Burnie, Md., ... painful for her. "This is why the co-inventor and I have designed a new ... then created a prototype of the patent-pending AV-AIR, a device that serves as an ...
(Date:12/7/2016)... ... XX, 2016 (PRWEB) (PRWEB) December 07, 2016 , ... Man’s ... Filamentous Dermatitis Associated with Borrelia Infection” reveals that a condition similar ... the prestigious Journal of Veterinary Science & Medical Diagnosis. , Morgellons disease is ...
(Date:12/7/2016)... ... December 07, 2016 , ... Facial plastic surgeon, Dr. John D. Rachel ... a portion of proceeds to two local organizations: North Chicago Animal Control and Friends ... is a team of authorized and trained volunteers who support rescued animals held ...
(Date:12/7/2016)... ... December 07, 2016 , ... 1105 Media’s Live ... the Folio: Marketing Awards competition. Live From won in the Use of Social ... and ultimately successful projects undertaken by the media industry’s most innovative marketing professionals. ...
Breaking Medicine News(10 mins):
(Date:12/6/2016)... 6, 2016 Homozygous Familial Hypercholesterolemia ... Summary Global Markets Direct,s latest Pharmaceutical ... Hypercholesterolemia (HoFH) – Pipeline Review, H2 2016, ... Hypercholesterolemia (HoFH) (Metabolic Disorders) pipeline landscape. ... which is caused due to mutation from ...
(Date:12/6/2016)... Colo. , Dec. 6, 2016   ... of cartilage, cellular, bone, skin and soft-tissue allografts ... Meyer , Business Process Manager, for being named ... Malcolm Baldrige National Quality Award by the Commerce ... deepening the organization,s commitment to process excellence. The ...
(Date:12/6/2016)... 2016 Two new disaster drones delivered telemedical ... mass casualty event Tuesday at John Bell Airport in ... before an audience including Mississippi ... Security, Federal Law Enforcement Agencies, and the United Nations. ... (Health Integrated Rescue Operations), was developed by Italo ...
Breaking Medicine Technology: