Navigation Links
Vitamin B1 could reverse early-stage kidney disease in diabetes patients
Date:12/8/2008

Researchers at the University of Warwick have discovered high doses of thiamine vitamin B1 can reverse the onset of early diabetic kidney disease.

Kidney disease, or diabetic nephropathy, develops progressively in patients with type 2 diabetes. Early development of kidney disease is assessed by a high excretion rate of the protein albumin from the body in the urine, known as microalbuminuria.

The research is led by Dr Naila Rabbani and Professor Paul J Thornalley at Warwick Medical School, University of Warwick, in collaboration with researchers at the University of Punjab and Sheik Zaid Hospital, Lahore, Pakistan.

The team has discovered taking high oral doses of thiamine can dramatically decrease the excretion of albumin and reverse early stage kidney disease in type 2 diabetes patients.

In a paper published online in the journal Diabetologia, the team show 300 mg of thiamine taken orally each day for three months reduced the rate of albumin excretion in type 2 diabetes patients. The albumin excretion rate was decreased by 41% from the value at the start of the study. The results also showed 35% of patients with microalbuminuria saw a return to normal urinary albumin excretion after being treated with thiamine.

Forty patients with type 2 diabetes aged between 35 and 65 years old took part in the trial. They were randomly assigned a placebo or 3 x 100mg tablets of thiamine a day for three months.

The Warwick research group has already conclusively proven that type 2 diabetes patients have a thiamine deficiency. In an earlier study led by Professor Paul Thornalley at Warwick Medical School, the research team showed that thiamine deficiency could be key to a range of vascular problems for diabetes patients.

Dr Rabbani said: "This study once again highlights the importance of Vitamin B1 and we need to increase awareness. Professor Thornalley and I are planning a foundation at the University of Warwick to further education and research in thiamine deficiency."


'/>"/>

Contact: Kelly Parkes-Harrison
k.e.parkes@warwick.ac.uk
44-078-245-40863
University of Warwick
Source:Eurekalert

Related medicine news :

1. Vitamin K Slows Insulin Resistance in Older Men
2. Aurora Health Care Urges All Wisconsin Residents to Take Vitamin D
3. American Academy of Dermatology Issues Position Statement on Vitamin D
4. Changing Times Vitamins to Sponsor Emmanuel Manny Pacquiao in Upcoming Fight With Oscar De La Hoya.
5. First and Only Single Capsule Daily Rx Prenatal Vitamin With Plant-Based DHA Now Available
6. Nordic Naturals Offers Cod Liver Oil Solutions in Response to Recent Vitamin A and Vitamin D Controversy
7. Vitamin D Vital for the Heart
8. Grassrootshealth Launches D*action Community Project to Solve Vitamin D Deficiency Crisis
9. Vitamin K linked to insulin resistance in older men
10. ClutchWave LLC Launches PricePlow.com: Price Shopping For Supplements and Vitamins
11. JavaFit, Distributors of Vitamin Infused Fresh Roasted Coffee, Announces Partnership With CLR Roasters
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/5/2016)... (PRWEB) , ... December 05, 2016 , ... ... ability of physical therapist assistants, under direct supervision of a licensed physical therapist, ... physical therapy receives a consultation and treatment plan from a licensed physical therapist ...
(Date:12/5/2016)... CHICAGO, IL (PRWEB) , ... December 05, 2016 , ... ... value to the individual looking to buy neoprene knee sleeves for lifting ... activity. The design focuses heavily on two main aspects to provide a higher quality ...
(Date:12/5/2016)... (PRWEB) , ... December 05, ... ... professional calibrations is an excellent way to ensure moisture measurements are consistently ... time-consuming and impractical. , Now, METTLER TOLEDO offers a solution: ...
(Date:12/5/2016)... ... 05, 2016 , ... Z-Medica, LLC, a leading developer and ... American College of Surgeons (ACS) to provide basic bleeding control instructor training to ... course is a pilot program that fulfills the intent of the White House’s ...
(Date:12/4/2016)... , ... December 02, 2016 , ... ... give patients better access to nutraceuticals and help doctors more efficiently manage their ... portal and practice management software platform for Integrative and Functional Medicine. , ...
Breaking Medicine News(10 mins):
(Date:12/5/2016)... 2016 The global  non-invasive prenatal testing market  is ... report by Grand View Research, Inc. Evolution of prenatal testing in the ... serum screening and invasive diagnostic testing to determine the likelihood of fetal ... the forecast period. Continue Reading ... ...
(Date:12/4/2016)... Blueprint Medicines Corporation (NASDAQ: BPMC ... kinase medicines for patients with genomically defined diseases, ... trial evaluating BLU-285, an investigational medicine for the ... Blueprint Medicines is developing BLU-285 as a potent, ... 90 to 95 percent of patients with SM ...
(Date:12/4/2016)... , Dec. 2, 2016  Former Attorney General of ... , a partner at the law firm of Kahn Swick ... investigation into Lannett Company, Inc. (NYSE: LCI ). ... published an article titled "U.S. Charges in Generic-Drug Probe to ... by the Justice Department, begun about two years ago, now ...
Breaking Medicine Technology: