Navigation Links
Vitamin B1 could reverse early-stage kidney disease in diabetes patients
Date:12/8/2008

Researchers at the University of Warwick have discovered high doses of thiamine vitamin B1 can reverse the onset of early diabetic kidney disease.

Kidney disease, or diabetic nephropathy, develops progressively in patients with type 2 diabetes. Early development of kidney disease is assessed by a high excretion rate of the protein albumin from the body in the urine, known as microalbuminuria.

The research is led by Dr Naila Rabbani and Professor Paul J Thornalley at Warwick Medical School, University of Warwick, in collaboration with researchers at the University of Punjab and Sheik Zaid Hospital, Lahore, Pakistan.

The team has discovered taking high oral doses of thiamine can dramatically decrease the excretion of albumin and reverse early stage kidney disease in type 2 diabetes patients.

In a paper published online in the journal Diabetologia, the team show 300 mg of thiamine taken orally each day for three months reduced the rate of albumin excretion in type 2 diabetes patients. The albumin excretion rate was decreased by 41% from the value at the start of the study. The results also showed 35% of patients with microalbuminuria saw a return to normal urinary albumin excretion after being treated with thiamine.

Forty patients with type 2 diabetes aged between 35 and 65 years old took part in the trial. They were randomly assigned a placebo or 3 x 100mg tablets of thiamine a day for three months.

The Warwick research group has already conclusively proven that type 2 diabetes patients have a thiamine deficiency. In an earlier study led by Professor Paul Thornalley at Warwick Medical School, the research team showed that thiamine deficiency could be key to a range of vascular problems for diabetes patients.

Dr Rabbani said: "This study once again highlights the importance of Vitamin B1 and we need to increase awareness. Professor Thornalley and I are planning a foundation at the University of Warwick to further education and research in thiamine deficiency."


'/>"/>

Contact: Kelly Parkes-Harrison
k.e.parkes@warwick.ac.uk
44-078-245-40863
University of Warwick
Source:Eurekalert

Related medicine news :

1. Vitamin K Slows Insulin Resistance in Older Men
2. Aurora Health Care Urges All Wisconsin Residents to Take Vitamin D
3. American Academy of Dermatology Issues Position Statement on Vitamin D
4. Changing Times Vitamins to Sponsor Emmanuel Manny Pacquiao in Upcoming Fight With Oscar De La Hoya.
5. First and Only Single Capsule Daily Rx Prenatal Vitamin With Plant-Based DHA Now Available
6. Nordic Naturals Offers Cod Liver Oil Solutions in Response to Recent Vitamin A and Vitamin D Controversy
7. Vitamin D Vital for the Heart
8. Grassrootshealth Launches D*action Community Project to Solve Vitamin D Deficiency Crisis
9. Vitamin K linked to insulin resistance in older men
10. ClutchWave LLC Launches PricePlow.com: Price Shopping For Supplements and Vitamins
11. JavaFit, Distributors of Vitamin Infused Fresh Roasted Coffee, Announces Partnership With CLR Roasters
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/20/2017)... , ... January 20, 2017 , ... Michael and Betsy ... Farber Cancer Institute. For Betsy, the clinical trial has been life-saving as she ... not worsened. , Betsy Brauser was diagnosed with ovarian cancer in 2009. She ...
(Date:1/20/2017)... ... ... “Mary Magdalene: Grace is Greater than Sin”: a unique and memorable piece ... “Mary Magdalene: Grace is Greater than Sin” is the creation of published author, Brenda ... women who had little knowledge of the female characters portrayed in the Holy Bible. ...
(Date:1/20/2017)... ... , ... “I Forgive You”: a fine examination of how God handles sin, including how ... published author, Stephen Miller, who, for over ten long years has been waiting to release ... Trinidad and Tobago, he has been serving the Lord for over twenty years, and he ...
(Date:1/20/2017)... ... ... enchanting tale that teaches children the true meaning of Christmas. “Journey to Christmas” is the ... devoted woman of faith. , “Becoming a parent changes you. In my case, the ... years, but actually doing it might have been a while in coming if it hadn’t ...
(Date:1/20/2017)... ... 2017 , ... “God's Miracle Man: Against All Odds”: an inspiring affirmation ... author, Keith C. A. Tucker, son of Minister Delores Pinnock and a Jamaican native ... Mark Hardy , “While sitting up in bed, I felt a pounding headache. It ...
Breaking Medicine News(10 mins):
(Date:1/20/2017)... , January 20, 2017 Stock-Callers.com today ... SGYP ), Novo Nordisk A/S (NYSE: ... and Pernix Therapeutics Holdings Inc. (NASDAQ: PTX ). ... Thursday, January 19 th , 2017, finishing near its session ... Index dropped over 0.7%, while shares of health care companies ...
(Date:1/20/2017)... LONDON , January 20, 2017 Avillion ... the appointment of Mark Weinberg , MD MBA as Chief ... , USA . ... Dr Weinberg has spent more than 17 ... "top 20" pharma companies to micro-cap biotech. Over the course of ...
(Date:1/19/2017)... -- The U.S. Food and Drug Administration today approved Trulance ... adult patients. "No one medication works for ... Beitz , M.D., director of the Office of Drug Evaluation ... "With the availability of new therapies, patients and their doctors ... ...
Breaking Medicine Technology: