Navigation Links
Vital Therapies Initiates Liver Stabilization Trial
Date:10/1/2009

SAN DIEGO, Oct. 1 /PRNewswire/ -- Vital Therapies, Inc. (VTI), today announced that the first subject has been enrolled in a pivotal trial of its ELAD human cell-based liver assist system at California Pacific Medical Center (CPMC) in San Francisco. Todd Frederick, MD, Director of Liver Support Services, is the principal investigator for the trial at CPMC.

It is anticipated that up to 20 leading academic liver centers in the United States and Europe will take part in the SILVER (Stabilization In LiVER disease) study. The SILVER protocol allows for enrollment of patients with chronic liver disease who have recently suffered an acute event leading to moderate to severe liver failure, as measured by the Model for End Stage Liver Disease score (MELD). MELD score is widely accepted as an indicator of liver function.

The SILVER Trial is focusing on stabilization of liver disease so patients can either recover with their own liver intact or live long enough for a liver transplant. Liver transplantation is the only therapy proven to affect survival of liver failure patients. However the shortage of donor livers and the high cost of transplantation create a need either to support regeneration of the patient's own liver or to maintain sufficient liver function until a transplant organ becomes available. This study evaluates whether ELAD can provide this support.

For more details on the SILVER Trial, please go to www.clinicaltrials.gov

More than 120 patients have so far been treated with ELAD in six clinical trials in the United States, United Kingdom and China. An application for approval to market ELAD in China was filed in September 2007 after a pivotal clinical trial in China. This application is under review by China's SFDA.

VTI is also operating a compassionate use program with cost recovery in the United States, United Kingdom and Singapore.

About Vital Therapies, Inc. and ELAD® (Extracorporeal Liver Assist Device)

Vital Therapies, Inc. (VTI) is a privately held, venture backed company, with cell culture facilities in San Diego, California and a wholly owned subsidiary in Beijing, China. VTI is developing the first human liver cell-based Extracorporeal Liver Assist Device (ELAD) to stabilize liver function in patients with severe liver failure. During ELAD therapy the patient's plasma flows inside hollow fiber cartridges containing the cells, which process toxins and synthesize proteins and metabolites that are key products of normal human liver function. VTI completed a pivotal trial and filed for market approval of ELAD in China in September 2007. ELAD is in investigational clinical trials in the United States and Europe.

For more information go to www.vitaltherapies.com

About California Pacific Medical Center

California Pacific Medical Center is one of the largest private, community based, not-for-profit, teaching medical centers in California and is a Sutter Health affiliate. It is a tertiary and quaternary referral center providing access to leading edge medicine while delivering the best possible personalized care. It provides a wide variety of services, including acute, post-acute and outpatient hospital care; hospice services; preventive and complementary care; and health education. Through its medical education program and research institute, physicians at California Pacific Medical Center are able to bring health care innovation to the bedside.

ELAD is a United States trademark of Vital Therapies, Inc.

SOURCE Vital Therapies, Inc.


'/>"/>
SOURCE Vital Therapies, Inc.
Copyright©2009 PR Newswire.
All rights reserved

Related medicine news :

1. Sexually satisfied women have better general well-being and more vitality
2. New Invacare SOLO2 Portable Oxygen Concentrator Available At Vitality Medical
3. Disability Advocates Call-Out Governor Schwarzenegger for Honoring Mother-In-Law While Cutting Vital Services
4. The Vitality Group Joins Efforts to Improve Health of U.S. Workforce
5. Emergency Preparedness Simulation Scenarios Developed for Disaster Training Utilizing Laerdals VitalSim(TM) Product Line
6. Frost & Sullivan: First Responders Communication Interoperability - A Vital Need for Life-Saving Services
7. Flintec Load Cell Design Helps to Create Vital Medical Solutions
8. Add Years to Your Life: Sign up for the AARP(R)/Blue Zones(R) Vitality Project to Be a Part of 6 Weeks to Longevity Kicking off on September 8th
9. Patient perception is vital when reporting medical errors
10. Vitality Health LLC Joins HealthySkinPortal Network
11. Gene vital to brains stem cells implicated in deadly brain cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/28/2017)... ... April 28, 2017 , ... Bill Howe started his sewer and drain company ... Tina Howe joined the team, the Bill Howe brand was born and they began ... and giving back to the San Diego community in which they worked, lived and ...
(Date:4/28/2017)... ... April 28, 2017 , ... Researchers at Moffitt ... ActiGraph’s CentrePoint Data Hub in a sample of participants enrolled in an ... and sleep monitoring solutions for the global scientific community. The company’s new CentrePoint ...
(Date:4/28/2017)... ... April 28, 2017 , ... Intellitec Solutions announced the ... implement a Microsoft Dynamics GP solution that integrates to their PointClickCare EHR software ... in long-term care, Brooke Grove now has the capability to achieve its goal ...
(Date:4/28/2017)... Mateo, CA (PRWEB) , ... April 28, 2017 , ... ... Area cities as diverse as Millbrae, Burlingame, and Palo Alto, is proud to announce ... allow interested persons to bookmark and read organized content on topics such as home ...
(Date:4/28/2017)... ... April 28, 2017 , ... Semrock’s highly popular ... premier online modeling resource for fluorescence microscopists and optical system designers, enabling The ... 5 years spanning the globe, SearchLight has become a tremendously popular tool for ...
Breaking Medicine News(10 mins):
(Date:4/25/2017)... April 25, 2017 Endo International plc (NASDAQ: ... 2017. Members of its senior management team will host a conference ... a.m. ET. The dial-in number to access the ... 509-7598, and the passcode is 6086379. Please dial in 10 minutes ... A replay of the call will be available from May ...
(Date:4/20/2017)... , April 20, 2017  Vivify Health, the ... devices, has been awarded a very significant patent for ... EMRs to continual care via digital health.  This landmark ... intellectual property and further secures Vivify,s position as the ... in 2009, was the first company to apply consumer ...
(Date:4/20/2017)... R.I. , April 20, 2017  CVS ... CVS), today unveiled a new store design to ... assortment of healthier food, health-focused products and expanded ... store to help customers discover new offerings. Together ... the next evolution of the customer experience at ...
Breaking Medicine Technology: