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Vision restoration therapy shown to improve brain activity in brain injured patients
Date:8/13/2007

Columbia University Medical Center researchers have demonstrated using functional magnetic resonance imaging (fMRI), that brain activity was increased in stroke and traumatic brain injury survivors who underwent Vision Restoration Therapy (VRT), a rehabilitative treatment that helps these patients recover lost vision. The data will be published online in the peer-reviewed journal Neurorehabilitation and Neural Repair on Aug. 14, 2007 at http://nnr.sagepub.com/pap.dtl.

Researchers, led by Randolph S. Marshall, M.D., M.S., associate professor of clinical neurology and acting director, Division of Stroke and Critical Care at Columbia University College of Physicians and Surgeons, examined the fMRIs of six patients aged 35-77 with vision loss on the same side of both eyes (called homonymous hemianopia) caused by stroke or traumatic brain injury. The therapy is based on visual stimulation, which the patient performs daily at home on a dedicated computer device. The fMRI data showed increased activity in visual processing areas of the brain as patients learned to detect stimuli in the borderzone between the seeing and non-seeing fields. This enhanced activity was identified one month after beginning treatment and suggests that the brain is responding accordingly.

This study is encouraging because the fMRI technique allowed us to see and compare the activity levels in specific regions of the brain before and during Vision Restoration Therapy. After examining the images, the increased activity levels demonstrate progress associated with the treatment, said Dr. Marshall. Based on these initial results, we will continue to investigate the relationship between the imaging findings and the degree to which vision is recovered.

The publication of Dr. Marshalls study in Neurorehabilitation and Neural Repair underscores the growing scientific evidence validating Vision Restoration Therapy. For hundreds
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Contact: Elizabeth Streich
eas2125@columbia.edu
212-305-6535
Columbia University Medical Center
Source:Eurekalert

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