Navigation Links
Viruses for a healthy pregnancy

Sequences of DNA in the human genome that originated from ancient viral infections have some surprising effects on our bodies and are even essential for a healthy pregnancy, according to an article in the February issue of Microbiology Today.

Retrovirus infections represent the most intimate host-pathogen relationship. The virus inserts a copy of its genome into the DNA of the host cell, resulting in an irreversible, stable and sometimes lifelong infection. If a sperm or egg cell is infected, the virus DNA can be passed down generations, permanently fixed in the germ line. As a result, an endogenous retrovirus (ERV) can exist for millions of years.

Over the course of evolution, retroviruses have invaded the germ-line of our ancestors on numerous occasions. Now, human ERVs (HERVs) make up around 8% of our genome, say Dr David Griffiths from the Moredun Research Institute and Ccile Voisset from the Facult de Mdecine et des Sciences de la Sant in France.

Although there are no viruses similar to these ancient pathogens currently infecting humans, there are some related viruses in animals. For a retrovirus to become part of the host genome it is usually inactivated by mutation or silencing so it does not express any proteins. An epidemic of neoplastic disease in Australian koalas is giving researchers the rare opportunity to study this process.

Recent work has provided some tantalizing evidence supporting the roles of HERVs in normal physiology and also in disease, says Dr Griffiths, they can be seen as bona fide human genes. Some HERVs may be crucial for a healthy pregnancy, whereas others have been linked to diseases like MS and cancer.

It is only recently that the abundance of HERVs has been recognised and we are learning that they can have significant functions, says Dr Griffiths.


Contact: Lucy Goodchild
Society for General Microbiology

Page: 1

Related medicine news :

1. New viruses to treat bacterial diseases -- My enemies enemy is my friend
2. Laser blasts viruses in blood
3. Novel virus detection identifies new viruses in study of respiratory infections and asthma attacks
4. Influenza: Insights into cell specificity of human vs. avian viruses
5. Common human viruses threaten endangered great apes
6. McMaster test detects the most prevalent respiratory viruses
7. Penn study finds pro-death proteins required to regulate healthy immune function
8. UCLA researchers identify markers that may predict diabetes in still-healthy people
9. Air pollution linked to cardiovascular risk indices in healthy young adults
10. Top Tips to Enjoy Healthy Latin Food Without Losing the Taste (Recipe)
11. Finicky Felines Award Four Stars to New Wellness(R) Healthy Indulgence Everyday Entrees
Post Your Comments:
(Date:10/13/2017)... CT (PRWEB) , ... October 13, 2017 , ... ... long-term care services, staged a mock evacuation of the facility as part of a ... Shelton Fire Department, Echo Hose EMS and Shelton City Emergency Manager, as well as ...
(Date:10/13/2017)... ... , ... Yisrayl Hawkins, Pastor and Overseer at The House of Yahweh, has ... least understood books in the Holy Scriptures, Revelation. The Book of Revelation paints a ... centuries. Many have tossed it off as mere rubbish, but Yisrayl Hawkins says that ...
(Date:10/12/2017)... ... October 12, 2017 , ... First Healthcare ... program management, will showcase a range of technology and learning solutions at the ... Convention and Expo to be held October 14–18, 2017 at the Mandalay Bay ...
(Date:10/12/2017)... ... October 12, 2017 , ... The American College of Medical Informatics (ACMI) ... FACMI, during the Opening Session of AMIA’s Annual Symposium in Washington, D.C. AMIA’s ... Morris F. Collen, a pioneer in the field of medical informatics, this prestigious award ...
(Date:10/12/2017)... ... October 12, 2017 , ... Leading pediatric oncology experts at ... for the 49th Congress of the International Society of Paediatric Oncology (SIOP) ... Center for Cancer and Blood Disorders at Children’s National, and Stephen P. ...
Breaking Medicine News(10 mins):
(Date:10/12/2017)... Pa. , Oct. 12, 2017 ... leader in innovative solutions for injectable drug administration, today ... before the market opens on Thursday, October 26, 2017, ... the results and business expectations at 9:00 a.m. Eastern ... (U.S.) or 253-336-8738 (International). The conference ID is 94093362. ...
(Date:10/10/2017)... , Oct. 10, 2017  NDS received FDA 510(k) clearance in ... medical-grade battery-powered display stand specifically designed for endoscopy environments. An innovative ... into a clinical solution to support the improvement of patient outcomes, ... Design ... Solution ...
(Date:10/4/2017)... 4, 2017  According to the Centers for Disease Control and Prevention ... . PhysicianOne Urgent Care is helping communities across Massachusetts ... , by offering no-cost* flu shots through the end of the month. ... health insurance regulations. ... to get a flu shot is by the end of October, according ...
Breaking Medicine Technology: