Navigation Links
Virus-like particles provide vital clues about brain tumors
Date:4/17/2013

"Current wisdom says that cells are closed entities that communicate through the secretion of soluble signalling molecules. Recent findings indicate that cells can exchange more complex information whole packages of genetic material and signalling proteins. This is an entirely new conception of how cells communicate", says Dr Mattias Belting, Professor of Oncology at Lund University and senior consultant in oncology at Skne University Hospital, Lund, Sweden.

Exosomes are small vesicles of only 30 nm. They are produced inside cells and act as "transport vehicles" of genetic material that can be transferred to surrounding cells. Since their first discovery, exosomes have been found in blood, saliva, urine, breast milk and other body fluids.

Mattias Belting's research group has investigated exosomes released from tumour cells of patients with gliomas.

The tiny exosome particles are delivered from the tumour to healthy cells of the brain and may prime normal tissue for efficient spreading of the tumour. The researchers in Lund have now shown that the aggressiveness of the tumour is reflected in the exosome molecular profile.

"We have succeeded in developing a method for the isolation of exosomes from brain tumour patients through a relatively simple blood test. Our analyses indicate that the content of exosomes mirrors the aggressiveness of the tumour in a unique manner", says postdoctoral researcher Paulina Kucharzewska.

Exosomes could thus be utilised as biomarkers, i.e. to provide guidance on how the patient should be treated and to monitor treatment response. This possibility is particularly attractive with brain tumours that are not readily accessible for tissue biopsy. However, analysis of exosomes from the blood may also prove important with other tumour types. The value of conventional tumour biopsies is limited by the heterogeneity of tumour tissue, i.e. the tissue specimen may not be fully representative of the
'/>"/>

Contact: Mattias Belting
mattias.belting@med.lu.se
46-467-335-07473
Lund University
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Applied nanobiomedicine: Exploiting nanoparticles to hunt for hidden cancer cells
2. Nanoparticles engineered at Notre Dame promise to improve blood cancer treatment
3. Researchers find gold nanoparticles capable of unzipping DNA
4. Higher energies for laser-accelerated particles possible
5. New nanoparticles shrink tumors in mice
6. UCSB scientists examine effects of manufactured nanoparticles on soybean crops
7. Improved nanoparticles deliver drugs into brain
8. Nanoparticles detect biochemistry of inflammation
9. UGA researchers boost efficacy of drugs by using nanoparticles to target powerhouse of cells
10. New electrically-conductive polymer nanoparticles can generate heat to kill colorectal cancer cells
11. Patients can emit small, influenza-containing particles into the air during routine care
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2015)... ... July 31, 2015 , ... Like nearly every other form of surgery, it ... made more effective and less intrusive and painful. Leading these advances in the ... Dr. Loria currently stands as the only doctor in the United States who is ...
(Date:7/31/2015)... ... July 31, 2015 , ... Florida Hospital Tampa ... that was developed for targeted delivery of fluids to selected sites in the ... Florida Hospital Tampa with the device that provides direct, local delivery of chemotherapy ...
(Date:7/31/2015)... ... July 31, 2015 , ... ... announce that their latest designer handbag line will be named for Madeline Stuart, ... sensation as the first globally recognized model with Down syndrome, gracing the front ...
(Date:7/31/2015)... ... July 31, 2015 , ... According to WFLA on July ... heroin use and eventual overdoses. Thricefold deaths have held steady over the last “couple ... the Sarasota heroin epidemic, which was spurred by the crackdown of prescription painkillers. Many ...
(Date:7/31/2015)... ... 31, 2015 , ... New Energy Works Timberframers invites the public to join ... 15th, 2015 from 9am – 12pm. Timber frame raisings are special, celebrating ... community as the culmination of months of effort, planning, fundraising, and dreaming takes shape. ...
Breaking Medicine News(10 mins):Health News:Loria Medical Penile Enlargement Center to Expand, Offering Practice Partnership to Doctors 2Health News:Florida Hospital Tampa Expands Treatment Options for Patients with Pancreatic Cancer Using New Catheter Technology 2Health News:Florida Hospital Tampa Expands Treatment Options for Patients with Pancreatic Cancer Using New Catheter Technology 3Health News:Florida Hospital Tampa Expands Treatment Options for Patients with Pancreatic Cancer Using New Catheter Technology 4Health News:everMaya to Launch Madeline Stuart Handbag Line 2Health News:everMaya to Launch Madeline Stuart Handbag Line 3Health News:Sarasota Sufferers Increased Heroin Overdoses and Deaths 2Health News:Sarasota Sufferers Increased Heroin Overdoses and Deaths 3Health News:Timber Frame Raising: Granary District Stage Amphitheater Timber Frame Hand-Raising by New Energy Works Timberframers 2Health News:Timber Frame Raising: Granary District Stage Amphitheater Timber Frame Hand-Raising by New Energy Works Timberframers 3
... , Salad Bar to Be Donated to ... , , WASHINGTON, Aug. 19 The ... bar at its Fresh Festival event, September 9, in the Cannon House ... salad bar, stocked with fresh fruits and vegetables, will underscore the need ...
... , , NEW YORK, Aug. ... point-of-care digital signage network into major U.S. markets, including Detroit, Miami, ... demand for HMN,s services by healthcare providers and advertisers. Installations in ... markets is slated for the second half of 2009. HMN,s largest ...
... experts say , WEDNESDAY, Aug. 19 (HealthDay ... with the drug letrozole (Femara) increases survival after surgery ... confirms. , Both letrozole and tamoxifen have been used ... with hormone receptor-positive cancer, but whether one drug is ...
... , , , ... and BRISBANE, Calif., Aug. 19 Roche (SIX: ROG.VX; RO.S, OTCQX: ... that the first patient has been dosed in a Phase 2b ... in combination with PEGASYS(R) (pegylated interferon alfa-2a) and COPEGUS(R) (ribavirin). ...
... (August 19, 2009) Using a novel robot-assisted endoscopic ... of Medicine in Seoul, Korea, has successfully treated 200 ... which has several technical and cosmetic benefits that the ... the August issue of the Journal of the ...
... paraffin, suggest beeswax instead , WEDNESDAY, Aug. 19 (HealthDay ... ambiance, fragrance and light, may also contribute to air ... made from petroleum, are a source of known human ... to be presented Wednesday at the American Chemical Society,s ...
Cached Medicine News:Health News:United Fresh to Feature Salad Bar at Capitol Hill Event to Advocate National School Salad Bar Policy 2Health News:United Fresh to Feature Salad Bar at Capitol Hill Event to Advocate National School Salad Bar Policy 3Health News:Health Media Network Expands to New Markets 2Health News:Newer Drug Beats Tamoxifen for Older Breast Cancer Patients 2Health News:Newer Drug Beats Tamoxifen for Older Breast Cancer Patients 3Health News:Roche and InterMune Initiate Phase 2b Clinical Trial of RG7227/ ITMN-191 in Patients With Chronic Hepatitis C 2Health News:Roche and InterMune Initiate Phase 2b Clinical Trial of RG7227/ ITMN-191 in Patients With Chronic Hepatitis C 3Health News:Roche and InterMune Initiate Phase 2b Clinical Trial of RG7227/ ITMN-191 in Patients With Chronic Hepatitis C 4Health News:Roche and InterMune Initiate Phase 2b Clinical Trial of RG7227/ ITMN-191 in Patients With Chronic Hepatitis C 5Health News:Roche and InterMune Initiate Phase 2b Clinical Trial of RG7227/ ITMN-191 in Patients With Chronic Hepatitis C 6Health News:Roche and InterMune Initiate Phase 2b Clinical Trial of RG7227/ ITMN-191 in Patients With Chronic Hepatitis C 7Health News:Roche and InterMune Initiate Phase 2b Clinical Trial of RG7227/ ITMN-191 in Patients With Chronic Hepatitis C 8Health News:Roche and InterMune Initiate Phase 2b Clinical Trial of RG7227/ ITMN-191 in Patients With Chronic Hepatitis C 9Health News:Roche and InterMune Initiate Phase 2b Clinical Trial of RG7227/ ITMN-191 in Patients With Chronic Hepatitis C 10Health News:New robot-assisted surgical method found successful for treatment of thyroid cancer 2
(Date:7/30/2015)... CHAGRIN FALLS, Ohio , July 30, 2015 /PRNewswire/ ... in his OMTEC® 2015 keynote address last month that ... business models in order to gain the efficiencies—and develop ... future. Dr. Barsoum,s comments were preceded by ... Tornier, avid entrepreneur and OMTEC moderator, who stressed that ...
(Date:7/30/2015)... , July 30, 2015 ... research report with market overview, trends, DRO ... porter analysis, recent developments, competitive scenario and ... Industry Insight: Biosensors Market Development and Demand ... http://photos.prnewswire.com/prnh/20150727/756778 ) Explore more ...
(Date:7/30/2015)... 2015 Vermillion, Inc. (VRML), a ... announced today it will report its second ... close on Thursday, August 13, 2015, followed ... at 4:30pm Eastern.Conference Call and Webcast:  ... Pacific  Domestic: , 888-430-8691International: ...
Breaking Medicine Technology:Orthopaedic Surgery Reimbursement Shifts to Episode of Care 2Global Biosensors Market (Size of $12,964 Million in 2014) to Witness 10% CAGR During 2015 - 2020 2Global Biosensors Market (Size of $12,964 Million in 2014) to Witness 10% CAGR During 2015 - 2020 3Global Biosensors Market (Size of $12,964 Million in 2014) to Witness 10% CAGR During 2015 - 2020 4Global Biosensors Market (Size of $12,964 Million in 2014) to Witness 10% CAGR During 2015 - 2020 5
... MILPITAS, Calif., May 5, 2011 AmbiCom ... wireless products for medical equipment suppliers, today announced that ... investor relations consulting firm, to develop and implement a ... strengthen its relationships with the investment community. ...
... SAN MATEO, Calif., May 5, 2011 NeurogesX, Inc. (NASDAQ: ... and commercializing novel pain management therapies, announced today that Anthony ... at the 10th Annual JMP Securities Research Conference, to be ... , 10th Annual JMP Securities Research Conference Date : ...
Cached Medicine Technology:AmbiCom Retains Hayden IR to Develop Strategic Investor Relations Program 2AmbiCom Retains Hayden IR to Develop Strategic Investor Relations Program 3NeurogesX to Present at 10th Annual JMP Securities Research Conference 2NeurogesX to Present at 10th Annual JMP Securities Research Conference 3
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: