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ViroPharma Announces Initiation Of Non-Toxigenic Clostridium Difficile Phase 1 Program
Date:8/6/2009

d Dale N. Gerding, MD, Associate Chief of Staff for Research at the Hines VA Hospital. "Despite the effectiveness of current acute treatment options, CDI recurrence remains a significant unmet medical need and NTCD presents a unique opportunity to not only reduce CDI recurrent disease but to also potentially prevent primary CDI in high-risk patients taking antibiotics."

About Clostridium difficile

One of the most serious problems facing the U.S. healthcare system today is hospital-acquired infections (HAIs) and Clostridium difficile infection is one of the most common and devastating HAIs. The incidence of Clostridium difficile observed in U.S. healthcare facilities more than doubled approximately every five years since 1999 and the reported mortality rates from Clostridium difficile in the U.S. have more than quadrupled in the last decade to 23.7 per million. Elderly patients exposed to antibiotics, long-term care patients, or those who have a serious underlying illness are at greatest risk to contract the disease. Patients with this disease have GI tract conditions that are significantly different from those of a healthy individual due to infection. Typical symptoms include diarrhea (which can be severe), fever, nausea, abdominal pain, and dehydration, though cases can lead to life-threatening complications such as megacolon, peritonitis and perforation of the colon.

About ViroPharma Incorporated

ViroPharma Incorporated is a biopharmaceutical company dedicated to the development and commercialization of products that address serious diseases treated by physician specialists and in hospital settings. ViroPharma commercializes Vancocin(R), approved for oral administration for treatment of antibiotic-associated pseudomembranous colitis caused by Clostridium difficile and enterocolitis caused by Staphylococcus aureus, including methicillin-r
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SOURCE ViroPharma Incorporated
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