Navigation Links
Virginia Tech scientists out for blood when it comes to stopping malaria
Date:3/19/2014

Fighting malaria in today's world will require a new, targeted approach, and Virginia Tech researchers are out for blood.

The parasites responsible for the mosquito-borne infectious disease are increasingly resistant to current drug approaches, and almost half of the world is at risk of contracting an illness.

Maria Belen Cassera, an assistant professor of biochemistry in the College of Agriculture and Life Sciences, and a Fralin Life Science Institute affiliate, examines the metabolism of the malaria-causing parasite Plasmodium falciparum in order to identify new drug targets.

Her newest project, funded by the National Institute of Allergy and Infectious Diseases of the National Institutes of Health, will look at the crucial time when malaria is transmitted when reproductive cell precursors known as gametocytes develop.

Specifically, she wants to understand the role that specific metabolites called isoprenoids play in the early stages of development.

"We think that understanding the role of isoprenoids during gametocytogenesis and identifying metabolic steps absent or sufficiently different from its human host will allow us to design more efficient drugs to block malaria transmission, which is one of the key components for malaria elimination and eradication," Cassera said.

The metabolic pathways that the parasite uses are not found in humans, so pathway-specific drugs would have little effect on the human host.

"Dr. Cassera has taken a leap forward in malaria research by identifying a unique pathway at an essential step in parasite development and transmission to mosquitoes," said Vern Schramm, the Ruth Merns Chair and Professor of Biochemistry at the Albert Einstein College of Medicine, and former postdoctoral mentor to Cassera. "Dr. Cassera is one of a select few scientists who can work productively at the level of parasite biochemistry, biology, drug discovery, transmission, and even primate models of the disease. Her talents have been justly recognized by support from the NIH."

Cassera is a member of the Virginia Tech Center for Drug Discovery, the Virginia Tech Vector-borne Disease Research Group, and the department of basic science at Virginia Tech Carilion School of Medicine.

She is also involved with the Translational Biology, Medicine, and Health graduate program as part of Virginia Tech's new faculty of health sciences.


'/>"/>

Contact: Lindsay Taylor Key
ltkey@vt.edu
540-231-6594
Virginia Tech
Source:Eurekalert  

Related medicine news :

1. Healthy Back Store Confirms Closure of East Tyson’s Virginia Location
2. New TGen, Virginia G. Piper Cancer Center study targets non-small cell lung cancer
3. TrueShred Partners With Virginia Commerce Bank To Host Shred Events and Securely Shred Documents and Files.
4. Hormone Replacement Clinic, Renew Health and Wellness Opens in Richmond, Virginia. New Center Specializes in Anti-Aging Therapies for both Women and Men.
5. Virginia Weight Loss Center "Best of the Best" Awarded to Obesity Surgery Center and to Dr. Osvaldo Anez by Follow Media Consulting, Inc.
6. Weight Loss Virginia "Best of the Best" Awarded to Obesity Surgery Center and to Dr. Osvaldo Anez by Follow Media Consulting, Inc.
7. Ring in the Noon Year at the Science Museum of Virginia
8. Worldwide Internet Sensation and Ashland Musician George Dennehy Performs at the Science Museum of Virginia
9. Marriage Counseling Virginia "Best of the Best" Awarded to Good Neighbor Community Services by Follow Media Consulting, Inc.
10. Virginia Hearing Consultants Now Makes Getting Hearing Aids in Norfolk, VA Easier With Complimentary Hearing Screenings
11. Counseling Virginia "Best of the Best" Awarded to Good Neighbor Community Services by Follow Media Consulting, Inc.
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Virginia Tech scientists out for blood when it comes to stopping malaria
(Date:6/25/2016)... ... June 25, 2016 , ... "With 30 hand-drawn hand ... project," said Christina Austin - CEO of Pixel Film Studios. , ProHand Cartoon’s ... within Final Cut Pro X . Simply select a ProHand generator and drag ...
(Date:6/25/2016)... , ... June 25, 2016 , ... ... and non-athletes recover from injury. Recently, he has implemented orthobiologic procedures as a ... area —Johnson is one of the first doctors to perform the treatment. Orthobiologics ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... A recent ... that most people are unfamiliar with. The article goes on to state that individuals ... also many of these less common operations such as calf and cheek reduction. The ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... Marcy was in a crisis. Her son ... lash out at his family verbally and physically. , “When something upset him, he couldn’t ... would use it. He would throw rocks at my other children and say he was ...
(Date:6/24/2016)... ... June 24, 2016 , ... Dr. ... accelerated orthodontic treatment. Dr. Cheng has extensive experience with all areas of orthodontics, ... and accelerated osteogenic orthodontics. , Micro-osteoperforation is a revolutionary adjunct to orthodontic ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... -- Jazz Pharmaceuticals plc (Nasdaq: JAZZ ) ... Improvements Act of 1976, as amended ("HSR"), with respect ... Nasdaq: CPXX ) expired effective June 24, ... As previously announced on May 31, 2016, Jazz Pharmaceuticals ... which Jazz Pharmaceuticals has commenced a tender offer for ...
(Date:6/24/2016)... SAN FRANCISCO, Calif. , June 24, 2016 ... GBT ), a biopharmaceutical company developing novel therapeutics ... significant unmet needs, today announced the closing of ... shares of common stock, at the public offering ... shares in the offering were offered by GBT. ...
(Date:6/24/2016)... June 24, 2016 Dehaier Medical Systems Ltd. ... which develops, markets and sells medical devices and wearable ... signed a strategic cooperation agreement with Hongyuan Supply Chain ... Chain") on June 20, 2016, to develop Dehaier,s new ... cooperation agreement, Dehaier will leverage Hongyuan Supply Chain,s sales ...
Breaking Medicine Technology: