Navigation Links
Virginia Tech scientists out for blood when it comes to stopping malaria
Date:3/19/2014

Fighting malaria in today's world will require a new, targeted approach, and Virginia Tech researchers are out for blood.

The parasites responsible for the mosquito-borne infectious disease are increasingly resistant to current drug approaches, and almost half of the world is at risk of contracting an illness.

Maria Belen Cassera, an assistant professor of biochemistry in the College of Agriculture and Life Sciences, and a Fralin Life Science Institute affiliate, examines the metabolism of the malaria-causing parasite Plasmodium falciparum in order to identify new drug targets.

Her newest project, funded by the National Institute of Allergy and Infectious Diseases of the National Institutes of Health, will look at the crucial time when malaria is transmitted when reproductive cell precursors known as gametocytes develop.

Specifically, she wants to understand the role that specific metabolites called isoprenoids play in the early stages of development.

"We think that understanding the role of isoprenoids during gametocytogenesis and identifying metabolic steps absent or sufficiently different from its human host will allow us to design more efficient drugs to block malaria transmission, which is one of the key components for malaria elimination and eradication," Cassera said.

The metabolic pathways that the parasite uses are not found in humans, so pathway-specific drugs would have little effect on the human host.

"Dr. Cassera has taken a leap forward in malaria research by identifying a unique pathway at an essential step in parasite development and transmission to mosquitoes," said Vern Schramm, the Ruth Merns Chair and Professor of Biochemistry at the Albert Einstein College of Medicine, and former postdoctoral mentor to Cassera. "Dr. Cassera is one of a select few scientists who can work productively at the level of parasite biochemistry, biology, drug discovery, transmission, and even primate models of the disease. Her talents have been justly recognized by support from the NIH."

Cassera is a member of the Virginia Tech Center for Drug Discovery, the Virginia Tech Vector-borne Disease Research Group, and the department of basic science at Virginia Tech Carilion School of Medicine.

She is also involved with the Translational Biology, Medicine, and Health graduate program as part of Virginia Tech's new faculty of health sciences.


'/>"/>

Contact: Lindsay Taylor Key
ltkey@vt.edu
540-231-6594
Virginia Tech
Source:Eurekalert  

Related medicine news :

1. Healthy Back Store Confirms Closure of East Tyson’s Virginia Location
2. New TGen, Virginia G. Piper Cancer Center study targets non-small cell lung cancer
3. TrueShred Partners With Virginia Commerce Bank To Host Shred Events and Securely Shred Documents and Files.
4. Hormone Replacement Clinic, Renew Health and Wellness Opens in Richmond, Virginia. New Center Specializes in Anti-Aging Therapies for both Women and Men.
5. Virginia Weight Loss Center "Best of the Best" Awarded to Obesity Surgery Center and to Dr. Osvaldo Anez by Follow Media Consulting, Inc.
6. Weight Loss Virginia "Best of the Best" Awarded to Obesity Surgery Center and to Dr. Osvaldo Anez by Follow Media Consulting, Inc.
7. Ring in the Noon Year at the Science Museum of Virginia
8. Worldwide Internet Sensation and Ashland Musician George Dennehy Performs at the Science Museum of Virginia
9. Marriage Counseling Virginia "Best of the Best" Awarded to Good Neighbor Community Services by Follow Media Consulting, Inc.
10. Virginia Hearing Consultants Now Makes Getting Hearing Aids in Norfolk, VA Easier With Complimentary Hearing Screenings
11. Counseling Virginia "Best of the Best" Awarded to Good Neighbor Community Services by Follow Media Consulting, Inc.
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Virginia Tech scientists out for blood when it comes to stopping malaria
(Date:2/27/2017)... TX (PRWEB) , ... February 27, 2017 , ... ... 75,000 customer threshold mark last week. In addition, Discount Power's RCE (Residential Customer ... Energy LLC in March 2014. The company had 800 customers and 2,250 RCEs ...
(Date:2/27/2017)... ... February 27, 2017 , ... Silicon Valley Hair ... announce a new informational post on robotic hair transplantation. San Francisco residents may ... transplant and Follicular Unit Transplantation (FUT) can sound similar. Either treatment can be ...
(Date:2/27/2017)... ... ... New Jersey ranks among the top five states in the entire nation ... advanced services is growing. , Project WE vs C is a focused two-year ... non-profit partners in their fight against cancer and in support of their shared mission ...
(Date:2/26/2017)... Como, Italy (PRWEB) , ... February 26, 2017 ... ... its last call for entries to the 7th Edition of International Social Design ... by Social Design Professionals, Product Designers, System Designers, Governments and Institutions worldwide with ...
(Date:2/26/2017)... ... February 26, 2017 , ... NuevaCare, a leading home care agency based in ... Palo Alto, is proud to announce an important upgrade to its geographic information pages, ... care close to home, and by having city-specific pages, NuevaCare is answering that information ...
Breaking Medicine News(10 mins):
(Date:2/24/2017)... 2017  Today, exocad America and the Biodenta ... new path to produce 510(K) cleared, in-house milled, ... integrated into exocad DentalCAD software. In order to ... Manufacturing Processes (GMP,s) into their organization, sign up ... an audit process. Then, dental labs can use Biodenta,s ...
(Date:2/24/2017)... Research and Markets has announced the addition of ... to 2025" report to their offering. ... The Global Empty Capsules Market is poised to grow ... approximately $2.9 billion by 2025. This industry report analyzes ... as well as regional levels presented in the research scope. The study ...
(Date:2/24/2017)... Feb. 24, 2017  In conjunction with DURECT Corporation,s ... results press release, you are invited to listen to ... the internet on Tuesday, March 14, 2017 at 4:30 ... A live audio webcast of the presentation will be ... and clicking "Investor Relations."  If you are unable to ...
Breaking Medicine Technology: