Navigation Links
Virginia Tech scientists out for blood when it comes to stopping malaria
Date:3/19/2014

Fighting malaria in today's world will require a new, targeted approach, and Virginia Tech researchers are out for blood.

The parasites responsible for the mosquito-borne infectious disease are increasingly resistant to current drug approaches, and almost half of the world is at risk of contracting an illness.

Maria Belen Cassera, an assistant professor of biochemistry in the College of Agriculture and Life Sciences, and a Fralin Life Science Institute affiliate, examines the metabolism of the malaria-causing parasite Plasmodium falciparum in order to identify new drug targets.

Her newest project, funded by the National Institute of Allergy and Infectious Diseases of the National Institutes of Health, will look at the crucial time when malaria is transmitted when reproductive cell precursors known as gametocytes develop.

Specifically, she wants to understand the role that specific metabolites called isoprenoids play in the early stages of development.

"We think that understanding the role of isoprenoids during gametocytogenesis and identifying metabolic steps absent or sufficiently different from its human host will allow us to design more efficient drugs to block malaria transmission, which is one of the key components for malaria elimination and eradication," Cassera said.

The metabolic pathways that the parasite uses are not found in humans, so pathway-specific drugs would have little effect on the human host.

"Dr. Cassera has taken a leap forward in malaria research by identifying a unique pathway at an essential step in parasite development and transmission to mosquitoes," said Vern Schramm, the Ruth Merns Chair and Professor of Biochemistry at the Albert Einstein College of Medicine, and former postdoctoral mentor to Cassera. "Dr. Cassera is one of a select few scientists who can work productively at the level of parasite biochemistry, biology, drug discovery, transmission, and even primate models of the disease. Her talents have been justly recognized by support from the NIH."

Cassera is a member of the Virginia Tech Center for Drug Discovery, the Virginia Tech Vector-borne Disease Research Group, and the department of basic science at Virginia Tech Carilion School of Medicine.

She is also involved with the Translational Biology, Medicine, and Health graduate program as part of Virginia Tech's new faculty of health sciences.


'/>"/>

Contact: Lindsay Taylor Key
ltkey@vt.edu
540-231-6594
Virginia Tech
Source:Eurekalert  

Related medicine news :

1. Healthy Back Store Confirms Closure of East Tyson’s Virginia Location
2. New TGen, Virginia G. Piper Cancer Center study targets non-small cell lung cancer
3. TrueShred Partners With Virginia Commerce Bank To Host Shred Events and Securely Shred Documents and Files.
4. Hormone Replacement Clinic, Renew Health and Wellness Opens in Richmond, Virginia. New Center Specializes in Anti-Aging Therapies for both Women and Men.
5. Virginia Weight Loss Center "Best of the Best" Awarded to Obesity Surgery Center and to Dr. Osvaldo Anez by Follow Media Consulting, Inc.
6. Weight Loss Virginia "Best of the Best" Awarded to Obesity Surgery Center and to Dr. Osvaldo Anez by Follow Media Consulting, Inc.
7. Ring in the Noon Year at the Science Museum of Virginia
8. Worldwide Internet Sensation and Ashland Musician George Dennehy Performs at the Science Museum of Virginia
9. Marriage Counseling Virginia "Best of the Best" Awarded to Good Neighbor Community Services by Follow Media Consulting, Inc.
10. Virginia Hearing Consultants Now Makes Getting Hearing Aids in Norfolk, VA Easier With Complimentary Hearing Screenings
11. Counseling Virginia "Best of the Best" Awarded to Good Neighbor Community Services by Follow Media Consulting, Inc.
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Virginia Tech scientists out for blood when it comes to stopping malaria
(Date:1/23/2017)... ... 2017 , ... Steviva Ingredients, makers of all-natural sweeteners and ... Organic Program (NOP) for its Portland SQF Level 2 manufacturing facility. , ... systems to complement our current rigorous food-safety management systems,” said Yishu Hou, quality ...
(Date:1/23/2017)... ... ... a story of love and redemption, hope and uncertainty as a girl makes her way ... at the Mill” is the creation of published author, Lois Kulp, who was born in ... County on Crow Hill. The inn, the mill and "Post Yokel" are within ...
(Date:1/23/2017)... ... 23, 2017 , ... Valentine’s Day is a time when many people celebrate romance and love ... may be looking for the ideal present, Atlanta-based Perimeter Plastic Surgery is offering ... free. Or, spend $200 and get $50 free. , “A lot of people just ...
(Date:1/21/2017)... Boca Raton, FL (PRWEB) , ... January 21, 2017 , ... ... Bump eRaiser, recently attended the January ECRM Trade Show in Hilton Head, SC, where ... an international reputation for the quality of its beauty and wellness products. At this ...
(Date:1/21/2017)... ... January 21, 2017 , ... Pacifica Graduate Institute’s Alumni ... line-up of events for its annual meeting “Coming Home 2017,” an activity-packed weekend ... Home 2017” will be held on Friday January 27 through Sunday, January 29, ...
Breaking Medicine News(10 mins):
(Date:1/21/2017)... According to a new market research report ... Compliance, SCM), Component (Software, Service), Delivery (On premise, Cloud), End user ... MarketsandMarkets, the market is expected to reach USD 24.73 Billion by ... 13.3% during the forecast period. Continue ... ...
(Date:1/21/2017)... Jan. 20, 2017  Today, during a ... "PI3K Pathways in Immunology, Growth Disorders and ... INFI ) presented preclinical data ... that selectively inhibits phosphoinositide-3-kinase-gamma (PI3K-gamma). Preclinical data ... overcome resistance to checkpoint inhibition by remodeling ...
(Date:1/21/2017)... , Jan. 20, 2017  Faruqi & Faruqi, LLP, ... Inc. ("KemPharm" or the "Company") (NASDAQ: KMPH ) ... Company and certain officers and directors and underwriters of the ... seek the role of lead plaintiff. The lawsuit ... District Court for Johnson County on ...
Breaking Medicine Technology: