Navigation Links
Virginia Tech scientists out for blood when it comes to stopping malaria
Date:3/19/2014

Fighting malaria in today's world will require a new, targeted approach, and Virginia Tech researchers are out for blood.

The parasites responsible for the mosquito-borne infectious disease are increasingly resistant to current drug approaches, and almost half of the world is at risk of contracting an illness.

Maria Belen Cassera, an assistant professor of biochemistry in the College of Agriculture and Life Sciences, and a Fralin Life Science Institute affiliate, examines the metabolism of the malaria-causing parasite Plasmodium falciparum in order to identify new drug targets.

Her newest project, funded by the National Institute of Allergy and Infectious Diseases of the National Institutes of Health, will look at the crucial time when malaria is transmitted when reproductive cell precursors known as gametocytes develop.

Specifically, she wants to understand the role that specific metabolites called isoprenoids play in the early stages of development.

"We think that understanding the role of isoprenoids during gametocytogenesis and identifying metabolic steps absent or sufficiently different from its human host will allow us to design more efficient drugs to block malaria transmission, which is one of the key components for malaria elimination and eradication," Cassera said.

The metabolic pathways that the parasite uses are not found in humans, so pathway-specific drugs would have little effect on the human host.

"Dr. Cassera has taken a leap forward in malaria research by identifying a unique pathway at an essential step in parasite development and transmission to mosquitoes," said Vern Schramm, the Ruth Merns Chair and Professor of Biochemistry at the Albert Einstein College of Medicine, and former postdoctoral mentor to Cassera. "Dr. Cassera is one of a select few scientists who can work productively at the level of parasite biochemistry, biology, drug discovery, transmission, and even primate models of the disease. Her talents have been justly recognized by support from the NIH."

Cassera is a member of the Virginia Tech Center for Drug Discovery, the Virginia Tech Vector-borne Disease Research Group, and the department of basic science at Virginia Tech Carilion School of Medicine.

She is also involved with the Translational Biology, Medicine, and Health graduate program as part of Virginia Tech's new faculty of health sciences.


'/>"/>

Contact: Lindsay Taylor Key
ltkey@vt.edu
540-231-6594
Virginia Tech
Source:Eurekalert  

Related medicine news :

1. Healthy Back Store Confirms Closure of East Tyson’s Virginia Location
2. New TGen, Virginia G. Piper Cancer Center study targets non-small cell lung cancer
3. TrueShred Partners With Virginia Commerce Bank To Host Shred Events and Securely Shred Documents and Files.
4. Hormone Replacement Clinic, Renew Health and Wellness Opens in Richmond, Virginia. New Center Specializes in Anti-Aging Therapies for both Women and Men.
5. Virginia Weight Loss Center "Best of the Best" Awarded to Obesity Surgery Center and to Dr. Osvaldo Anez by Follow Media Consulting, Inc.
6. Weight Loss Virginia "Best of the Best" Awarded to Obesity Surgery Center and to Dr. Osvaldo Anez by Follow Media Consulting, Inc.
7. Ring in the Noon Year at the Science Museum of Virginia
8. Worldwide Internet Sensation and Ashland Musician George Dennehy Performs at the Science Museum of Virginia
9. Marriage Counseling Virginia "Best of the Best" Awarded to Good Neighbor Community Services by Follow Media Consulting, Inc.
10. Virginia Hearing Consultants Now Makes Getting Hearing Aids in Norfolk, VA Easier With Complimentary Hearing Screenings
11. Counseling Virginia "Best of the Best" Awarded to Good Neighbor Community Services by Follow Media Consulting, Inc.
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Virginia Tech scientists out for blood when it comes to stopping malaria
(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... Apple ... care services, staged a mock evacuation of the facility as part of a disaster ... Fire Department, Echo Hose EMS and Shelton City Emergency Manager, as well as the ...
(Date:10/13/2017)... , ... October 13, 2017 , ... Global Healthcare Management’s ... Alexandria Park in Milford, NJ. This free event, sponsored by Global Healthcare Management’s ... The fun run is geared towards children of all ages; it is a ...
(Date:10/13/2017)... ... October 13, 2017 , ... “The Journey: From the ... danger possible to save lost souls in the Philippines. “The Journey: From the Mountains ... a dedicated teacher of the Bible. She has taught all ages and currently teaches ...
(Date:10/12/2017)... ... October 12, 2017 , ... Planet Fitness, one of the largest and ... plans to open a flagship location in Covington, LA at 401 N. U.S. Highway ... store next to Office Depot in the Holiday Square shopping center. Its location allows ...
(Date:10/12/2017)... ... 2017 , ... Asante, a nationally recognized health system in ... existing home health joint venture through an agreement, effective October 1, 2017, to ... home health company with Asante, delivering clinically integrated care, for the past eight ...
Breaking Medicine News(10 mins):
(Date:10/10/2017)... -- NDS received FDA 510(k) clearance in May 2017 for its highly ... designed for endoscopy environments. An innovative secondary monitor solution, ZeroWire ... support the improvement of patient outcomes, procedural efficiency, and the lowering ... ... ...
(Date:10/4/2017)... 4, 2017  South Korean-based healthcare product Development Company ... "cprCUBE" on Kickstarter. The device will educate the user ... with better efficiency compared to the dated and pricey ... on efficacy of the compression for a more informed ... goal to raise $5,000. ...
(Date:10/2/2017)... 2017  Eli Lilly and Company (NYSE: ... third quarter of 2017 on Tuesday, October 24, 2017. ... day with the investment community and media to further ... call will begin at 9 a.m. Eastern time. Investors, ... webcast of the conference call through a link that ...
Breaking Medicine Technology: