Navigation Links
Virginia G. Piper Charitable Trust and Flinn Foundation launch molecular diagnostics initiative

PHOENIX, Oct. 17, 2007 Two Arizona-based philanthropic organizations have committed $45 million to fund an innovative initiative to develop personalized molecular diagnostics. The ability to diagnose and treat disease based on every persons unique physiological makeup is critical to enabling physicians to improve health outcomes while at the same time reducing medical costs.

Under the Partnership for Personalized Medicine, The Virginia G. Piper Charitable Trust has committed $35 million and the Flinn Foundation has granted $10 million to bring together a wide range of resources to advance a global personalized medicine initiative.

World-renowned scientist Dr. Lee Hartwell, 2001 Nobel laureate and director of Fred Hutchinson Cancer Research Center, has been recruited to lead this effort. The Hutchinson Center, based in Seattle, is a leader in using molecular diagnostics for the early detection and clinical management of cancer and other diseases. In addition to his current position as president and director of Fred Hutchinson Cancer Research Center, he will chair the Partnership executive committee, which includes Dr. George Poste, director of the Biodesign Institute at Arizona State University, and Dr. Jeffrey Trent, president and scientific director of the Translational Genomics Research Institute (TGen).

It is a tremendous opportunity for me to be a part of this new model for improving health while reducing health care costs that is being funded by the Piper and Flinn foundations, Hartwell said. The collaboration between TGen, the Biodesign Institute at ASU, other institutions in Arizona and Fred Hutchinson Cancer Research Center brings together enormous expertise to tackle major challenges in bringing new science and technology to disease management.

The cornerstone of the Partnership is the creation of the Virginia G. Piper Center for Personalized Diagnostics that draws upon the scientific strengths of two of the states leading bioscience entities, TGen and the Biodesign Institute at ASU, each of which will contribute significant laboratory space to the effort. The Piper Center will utilize bioinformatics and high-performance computing expertise at both institutions, existing nanotechnology and imaging expertise at the Biodesign Institute, and supercomputing resources through ASUs Ira A. Fulton School of Engineering.

Additionally, an industrial scale, high-throughput proteomics production facility will be established that taps expertise at both TGen and the Biodesign Institute at ASU in robotics, protein analysis and computing.

Hartwells involvement provides the Piper Center with opportunity to draw on the Hutchinson Centers extensive capabilities in health economics and the design of clinical and public-health trials through consultative and collaborative relationships.

The Piper trustees made this investment because Dr. Hartwell has a vision to transform the prevention, diagnosis and treatment of disease, said Dr. Judy Jolley Mohraz, president and CEO of the Piper Trust. That vision draws together scientists, clinicians, engineers, statisticians, insurers and regulators to work collectively to make health care more targeted and affordable. This initiative holds the promise of making a difference in the quality of life for people here in Arizona and throughout the world.

According to John Murphy, president and CEO of the Flinn Foundation, biomarker discovery and diagnostic development could ultimately lead to earlier disease detection and more precise disease management. To leverage Arizonas institutional assets, the Flinn Foundations grant commitment to TGen will link Arizonas research universities, health care providers, research institutes and industry partners throughout the state to support the collection and storage of biospecimens and drive Arizona-centric demonstration projects, Murphy said.

Approximately 50 percent of the Flinn Fund for Arizona Proteomics Research will be available to promote research collaborations to leverage the states significant institutional resources in this field, Murphy added, with the balance supporting the creation of a high-throughput proteomics production facility."

Proteomics is a promising and cutting-edge field that studies proteins and their functions in the body. The proteomics production facility will focus on discovering new proteins for the development of diagnostic tests for patients with cancer or other illnesses. These tests could ultimately lead to earlier disease detection and more precise disease management.

Even though the necessary technologies to develop personalized diagnostic tests are available, barriers such as the expense of clinical trials and difficulty obtaining clinical samples have significantly slowed the development process. The Partnership will focus on the development, testing and validation of new molecular diagnostic tools and the approval and distribution of these tools for widespread clinical use. This will be accomplished through a series of collaborative demonstration projects that integrate key health organizations.

The Holy Grail of personalized medicine includes blood-based tests that improve diagnosis and help direct clinical care, said Trent. The unparalleled opportunity the Partnership provides is to expand the magnitude of proteomic studies across a spectrum of key clinical questions.

The Partnership includes recruitment of new faculty and will engage national and international partners to ensure developments are rapidly commercialized.

With the team of scientific and clinical research excellence we are assembling, our goal is to transform medicine from the current one size fits all approach to one that is targeted around a patients unique genetic and molecular profile, Poste said.

Partnerships formed with large health care systems and disease-focused foundations will facilitate the implementation and validation of molecular diagnostics in clinical settings, as well as close ongoing interaction between scientists and clinicians. Health care systems will benefit from newly developed diagnostics through the most cost-effective use of medical treatments, while patients and the public in general will enjoy greater overall health outcomes.

ASU President Michael Crow added that this endeavor promises to become a shining example of how multiple partners can work together to address a critical need in human health and accelerate solutions that extend beyond our own community.


Contact: Galen Perry
The Translational Genomics Research Institute

Related medicine news :

1. Once a Lawn Mower, a Self-made Billionaire Makes a Lasting Gift to Virginia Tech
2. West Virginia Organizes a Program to Fight Obesity
3. Indians Add to Rich Diversity of Virginia Tech
4. Virginia Tech. Shooter -Human Rights or Innocent Lives
5. Virginia Tech Shooters Mental Health Records No More Secret
6. Fire Ants are Emerging Nuisance for Virginians
7. Australian Devises Online Game Based on Virginia Tech Shootout
8. Pain Doctor in Virginia Sentenced to Five Years Imprisonment
9. Five Killed by Methane Gas on Virginia Farm
10. Trust In Doctors Can Affect Taking Medications
11. Repeated checking causes memory distrust
Post Your Comments:
(Date:11/27/2015)... ... November 27, 2015 , ... The rapid speed ... As people age, more care is needed, especially with Alzheimer’s, dementia and other ... are being overworked. The forgotten part of this equation: 80 percent of medical ...
(Date:11/27/2015)... (PRWEB) , ... November 27, 2015 , ... ... a safe and convenient way to dispense prescription medications at home, so he ... effective way to monitor and dispense prescription medications. In doing so, it could ...
(Date:11/27/2015)... ... November 27, 2015 , ... Lizzie’s Lice Pickers just ... is offering customers 10% off of their purchase of lice treatment product. In addition, ... price. According to a company spokesperson. “Finding lice is a sure way to ruin ...
(Date:11/27/2015)... ... 27, 2015 , ... ProSidebar: Fashion is a set of 30 ... ProSidebar: Fasion, video editors can easily add an informative sidebar to any FCPX production. ... Utilize presets featuring self-animating drop zones, lines, bars, and text with the ease of ...
(Date:11/27/2015)... , ... November 27, 2015 , ... ... of progress through sharing, the 2016 Building Better Radiology Marketing Programs ... will begin on Sunday, March 6, 2016, at Caesars Palace in Las Vegas ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... 26, 2015 Research and Markets ( ) ... Pacemaker Market Outlook to 2019 - Rise in Cardiac Disorders ... report to their offering. Boston ... Boston scientific and others. --> ... Biotronik, Boston scientific and others. ...
(Date:11/26/2015)... , November 26, 2015 ... of the "2016 Future Horizons and ... Abuse Testing Market: Supplier Shares, Country Segment ... to their offering. --> ... "2016 Future Horizons and Growth Strategies ...
(Date:11/26/2015)... STOCKHOLM , November 26, 2015 /PRNewswire/ ... --> Juntendo universitetssjukhus ser potential att ... av magnetresonansbilder (MR-bilder) för patienter med ... tecknat ett forskningsavtal med SyntheticMR AB för ... kliniska forskningsprojekt på sjukhuset. Med SyMRI kan ...
Breaking Medicine Technology: