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Virginia Commonwealth University to Study Genomics-Based Diagnostic Test:
Date:11/6/2007

Pathwork Diagnostics' Tissue of Origin Test Designed to Aid in

Determination of a Tumor's Origin

SUNNYVALE, Calif., Nov. 6 /PRNewswire/ -- Pathwork Diagnostics, a genomics-based diagnostics company focused on oncology, announced today that Virginia Commonwealth University School of Medicine has initiated an investigational study of the Pathwork(TM) Tissue of Origin Test. The new genomics-based test is designed to help determine a tumor's origin so that tissue-specific management can begin. VCU's study makes it one of the first institutions in the country to evaluate this leading technology in patients who may have few remaining diagnostic options. The Tissue of Origin Test is also the focus of two workshops and two poster presentations at the 12th Annual Meeting of the Association for Molecular Pathology this week (November 7-10, Los Angeles).

"Patient cases in which a tumor cannot be readily identified are a significant problem," said Catherine Dumur, Ph.D., Director of Molecular Morphology Genomics for the Department of Pathology, VCU. "Such cases are time-consuming for physicians and anxiety-producing for patients, and are a challenge to providing the most appropriate care for the patient. We are eager to see how this investigational new genomics-based test extends and complements traditional histopathological approaches."

There are an estimated 200,000 cancer patients each year in the United States who may benefit from additional diagnostic information to determine the tissue of origin for their cancer. National Comprehensive Cancer Network guidelines emphasize the importance of identifying the tissue of origin so that management specific to the primary cancer can begin.

"We envision that in the future genomics data will become a useful ancillary tool to pathologists to answer complex cancer questions in a clinical setting," said Carleton Garrett, M.D. Ph.D., Director of the Tissue and Data Acquisition an
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SOURCE Pathwork Diagnostics
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