Navigation Links
Viral protein structure study offers HIV therapy hope
Date:6/22/2010

The UK's National Physical Laboratory (NPL) is involved in a collaborative project that is helping to further the understanding of HIV viral protein structure which could lead to new molecular medicines.

In May 2010 the project team, comprising biotechnology experts from NPL, the University of Edinburgh and IBM T.J. Watson Research Center, published some of their research in Journal of Physical Chemistry B.

The article sets out to resolve controversy over how part of an HIV protein is structured. The research team present a definitive structure of the protein, which was obtained using experimental techniques and computer simulation. It is important to know exactly how viral proteins are structured so that drug developers can target weaknesses within it, and therefore devise better treatments for people.

NPL's Eleonora Cerasoli says: "In this research, we were looking at a part of the HIV virus that helps it fuse with, and then infect, healthy cells within the human body. By confirming the structure of this tiny, but significant, fragment of the HIV-1 protein we are helping to shed more light on its infection mechanism. Further work in this area will hopefully lead to a full understanding of exactly how it works, and therefore lead to better treatments for HIV."

To continue their efforts to understand the interactions between human cells and the HIV virus proteins, the research team will also be using the unique synchrotron facility available at Diamond Light Source. The insight this provides may help enable the next steps towards rational drug design and commercial exploitation.

This study is the first outcome of different investigations the research team are carrying out on biomedically important model systems. The overall scope, therefore, goes beyond understanding HIV's structure alone. The team are working on establishing structure-activity relationships which will further our understanding and treatment of other diseases, such as Alzheimer's.


'/>"/>

Contact: Joe Meaney
joe@proofcommunication.com
084-568-01864
National Physical Laboratory
Source:Eurekalert

Related medicine news :

1. NVHR: Administrations 2011 Budget Proposal Shortchanges Five Million Americans Afflicted with Chronic Viral Hepatitis
2. Researchers find broad spectrum antiviral that fights multitude of viruses
3. Immune memory formation seen in early stages of viral infection
4. NVHR Issues Challenge to Administration, Congress: Dont Leave 5 Million Americans Afflicted with Chronic Viral Hepatitis Out in the Cold with Budget Freeze
5. Vaccination, antivirals and social distancing may blunt impact of H1N1 influenza
6. New License Agreement with University of Colorado Gives Viral Genetics, Inc., Right to Develop Cancer Therapies
7. High antiretroviral therapy adherence associated with lower health care costs
8. New Study: Improved Immune System with Gene-Eden, a Natural Antiviral Supplement that Targets Chronic Viruses
9. Bipartisan Capitol Hill Media Event: Health Experts, Lawmakers to Urge Federal Government to Fix the Funding Failure for Chronic Viral Hepatitis
10. Acupuncture may be an effective treatment for post-viral infection loss of smell
11. UNC study offers first clinical evidence of anti-cancer drug triggering viral infection
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/23/2017)... (PRWEB) , ... June 23, 2017 , ... 21 Middle ... (EF) has selected 21 leaders from government, business and civil society in 11 ... in the U.S. this fall, engaging in a transformative exchange of knowledge and ideas ...
(Date:6/23/2017)... , ... June 23, 2017 , ... American Farmer, will ... series, which is slated to air fourth quarter 2017. American Farmer airs Tuesdays at ... Hansen, a Danish pharmacist, founded Chr. Hansen in Denmark in 1874 after a groundbreaking ...
(Date:6/23/2017)... ... ... All-Star Insurance, a family managed agency that offers insurance management assistance and personal ... of a new charity drive to benefit women in the area diagnosed with breast ... estimated 252, 710 new cases of invasive or high risk breast cancer will be ...
(Date:6/22/2017)... , ... June 22, 2017 , ... Plastic Surgery Associates ... a Top Doctor for 2017. Each year, research and information firm, Castle Connolly, releases ... the title in 2015, this marks the 3rd time that Dr. Canales ...
(Date:6/22/2017)... (PRWEB) , ... June 23, 2017 , ... Despite its ... to few reviews available that integrate basic science with clinical practice. Now, however, a ... aimed at providing clinicians with insight into the etiology of NeuP and educating preclinical ...
Breaking Medicine News(10 mins):
(Date:6/16/2017)... , June 16, 2017  Exactly 50 years ago ... off what later became known as the San Francisco "Summer ... ) is unveiling two radical innovations in strategic market research ... This announcement marks the beginning of Northern Light,s "Summer of ... ...
(Date:6/12/2017)... , June 12, 2017 Kineta, Inc., a biotechnology ... Kineta Vice President of R&D and Head of ... Pandemic Preparedness for the Northwest and Beyond meeting ... on June 14, 2017 from 8:30-10:30 AM PDT at the ... Dr. Bedard will be joined by other ...
(Date:6/8/2017)... MAITLAND, Fla. , June 8, 2017  Less ... ransomware attack that hit more than 200,000 companies, including hospital ... is being heralded as one of the largest online ... technology in the healthcare market, it is imperative that ... can protect their data from this — and many ...
Breaking Medicine Technology: