Navigation Links
Viral protein structure study offers HIV therapy hope
Date:6/22/2010

The UK's National Physical Laboratory (NPL) is involved in a collaborative project that is helping to further the understanding of HIV viral protein structure which could lead to new molecular medicines.

In May 2010 the project team, comprising biotechnology experts from NPL, the University of Edinburgh and IBM T.J. Watson Research Center, published some of their research in Journal of Physical Chemistry B.

The article sets out to resolve controversy over how part of an HIV protein is structured. The research team present a definitive structure of the protein, which was obtained using experimental techniques and computer simulation. It is important to know exactly how viral proteins are structured so that drug developers can target weaknesses within it, and therefore devise better treatments for people.

NPL's Eleonora Cerasoli says: "In this research, we were looking at a part of the HIV virus that helps it fuse with, and then infect, healthy cells within the human body. By confirming the structure of this tiny, but significant, fragment of the HIV-1 protein we are helping to shed more light on its infection mechanism. Further work in this area will hopefully lead to a full understanding of exactly how it works, and therefore lead to better treatments for HIV."

To continue their efforts to understand the interactions between human cells and the HIV virus proteins, the research team will also be using the unique synchrotron facility available at Diamond Light Source. The insight this provides may help enable the next steps towards rational drug design and commercial exploitation.

This study is the first outcome of different investigations the research team are carrying out on biomedically important model systems. The overall scope, therefore, goes beyond understanding HIV's structure alone. The team are working on establishing structure-activity relationships which will further our understanding and treatment of other diseases, such as Alzheimer's.


'/>"/>

Contact: Joe Meaney
joe@proofcommunication.com
084-568-01864
National Physical Laboratory
Source:Eurekalert

Related medicine news :

1. NVHR: Administrations 2011 Budget Proposal Shortchanges Five Million Americans Afflicted with Chronic Viral Hepatitis
2. Researchers find broad spectrum antiviral that fights multitude of viruses
3. Immune memory formation seen in early stages of viral infection
4. NVHR Issues Challenge to Administration, Congress: Dont Leave 5 Million Americans Afflicted with Chronic Viral Hepatitis Out in the Cold with Budget Freeze
5. Vaccination, antivirals and social distancing may blunt impact of H1N1 influenza
6. New License Agreement with University of Colorado Gives Viral Genetics, Inc., Right to Develop Cancer Therapies
7. High antiretroviral therapy adherence associated with lower health care costs
8. New Study: Improved Immune System with Gene-Eden, a Natural Antiviral Supplement that Targets Chronic Viruses
9. Bipartisan Capitol Hill Media Event: Health Experts, Lawmakers to Urge Federal Government to Fix the Funding Failure for Chronic Viral Hepatitis
10. Acupuncture may be an effective treatment for post-viral infection loss of smell
11. UNC study offers first clinical evidence of anti-cancer drug triggering viral infection
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/27/2016)... ... ... "FCPX editors can now reveal their media with growing colorful split screen ... - CEO of Pixel Film Studios. , ProSlice Color brings the split screens ... reveal the media of their split screens with growing colorful panels. , ProSlice Color ...
(Date:6/27/2016)... ... June 27, 2016 , ... TopConsumerReviews.com recently awarded their highest five-star rating to ... of individuals in the United States and Canada wear eyeglasses. Once considered to be ... vision and make a fashion statement. Even celebrities use glasses as a way of ...
(Date:6/26/2016)... ... June 26, 2016 , ... PawPaws brand pet supplements owned ... developed to enhance the health of felines. The formula is all-natural and is made ... in the PawPaws Cat Kidney Support Supplement Soft Chews are Astragalus Root ...
(Date:6/25/2016)... ... June 25, 2016 , ... Austin residents seeking Mohs surgery services, ... Mohs Surgery and to Dr. Russell Peckham for medical and surgical dermatology. , Dr. ... skin cancer. The selective fellowship in Mohs Micrographic Surgery completed by Dr. Dorsey was ...
(Date:6/25/2016)... CA (PRWEB) , ... June 25, 2016 , ... As ... with Magna Cum Laude and his M.D from the David Geffen School of Medicine ... and returned to Los Angeles to complete his fellowship in hematology/oncology at the UCLA-Olive ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... 23, 2016 Revolutionary technology includes ... Oticon , industry leaders in advanced audiology and hearing ... Oticon Opn ™, the world,s first internet connected hearing ... IoT devices.      (Photo: http://photos.prnewswire.com/prnh/20160622/382240 ... number of ,world firsts,: , TwinLink™ - ...
(Date:6/23/2016)... Research and Markets has announced ... Analysis (United States, China, Japan, Brazil, United Kingdom, Germany, ... offering. Surgical Procedure ... planners, provides surgical procedure volume data in a geographic ... in-depth analysis of growth drivers and inhibitors, including world ...
(Date:6/23/2016)... , June 23, 2016  The National ... has joined the health policy research organization as ... Romano , MD, senior vice president and chief ... company,s representative on the NPC Board of Directors. ... pleased that Mallinckrodt has joined us in support ...
Breaking Medicine Technology: