Navigation Links
Viral infections in infancy are not associated with wheezing symptoms in later childhood
Date:5/23/2012

ATS 2012, SAN FRANCISCO The number of viral infections during infancy is not associated with wheezing later in childhood, according to a new study from researchers in the Netherlands. While viral illnesses with wheezing in infancy predicted wheezing later in childhood, this association was due in part to decreased neonatal lung function.

"Viral infections in infancy, particularly rhinovirus, are thought to be a risk factor for later asthma development, but it is unclear whether this association is due to the viruses themselves or whether rhinovirus-associated wheeze is merely an indicator of disease susceptibility," said Anne van der Gugten, MD, a researcher at the University Medical Center Utrecht. "Accordingly, we examined the association between viruses during the first year of life independent of symptoms and the subsequent development of wheezing symptoms in childhood."

The results of the study will be presented at the ATS 2012 International Conference in San Francisco.

In the prospective, population-based birth cohort study, 96 children were followed from infancy through age four. Nose and throat swabs were collected at the beginning of every month during the first year of life, independent of the occurrence of symptoms. Pre-symptomatic lung function was assessed at the age of two months using the single occlusion technique.

Of 96 children, 13 (13.5%) had wheezing illnesses at age four. Compared to children without wheezing at age four, those with wheezing had decreased neonatal lung function. Children with wheezing at age four had a median of four human rhinovirus (HRV) infections in their first year, compared with a median of five among children without wheezing.

Neither the number of HRV infections in infancy nor the number of viral infections in general were associated with an increased risk of wheezing at age four. While a higher number of viral episodes with wheezing or a higher number of HRV episodes with wheezing was associated with an increased risk of wheezing at age four, these associations were not significant after adjustment for neonatal lung function.

"A number of prospective studies in high-risk cohorts have shown that viral wheezing illnesses, especially those caused by rhinovirus, are the most important predictors of the subsequent development of wheezing or asthma in childhood," said Dr. van der Gugten, "but it is unclear if rhinovirus is causally related to the development of asthma."

"Our study is the first to examine the association between viruses in infancy independent of symptoms and wheezing symptoms in childhood," said Dr. van der Gugten. "Our findings indicate that viral infections by themselves may not be associated with the development of asthma, but that children with reduced neonatal lung function are prone to experience wheezing during viral infections in infancy and to have asthma in childhood."

"Future research into the relationship between rhinovirus and wheezing disorders should account for factors that might modify this relationship, including neonatal lung function," Dr. van der Gugten concluded.


'/>"/>

Contact: Nathaniel Dunford
ndunford@thoracic.org
212-315-8620
American Thoracic Society
Source:Eurekalert

Related medicine news :

1. New Study: Improved Immune System with Gene-Eden, a Natural Antiviral Supplement that Targets Chronic Viruses
2. Bipartisan Capitol Hill Media Event: Health Experts, Lawmakers to Urge Federal Government to Fix the Funding Failure for Chronic Viral Hepatitis
3. Acupuncture may be an effective treatment for post-viral infection loss of smell
4. UNC study offers first clinical evidence of anti-cancer drug triggering viral infection
5. Viral Infection Could Be Marker for Type 1 Diabetes
6. Antiviral therapy during compensated cirrhosis most cost-effective approach
7. Longer Antiviral Therapy Reduces Lung Transplant Complications
8. Antiretrovirals During Breast-Feeding Shield Babies From HIV, Study Shows
9. Viral protein structure study offers HIV therapy hope
10. Texas A&M researcher explains how embryo fights retroviral infection
11. Vanishing bile duct syndrome secondary to anti-retroviral therapy in HIV
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... October 13, 2017 , ... As health professionals work to improve ... engagement.” The patient is doing more than filling out a survey; in many cases ... an increasing emphasis in health care and research on the importance of active engagement ...
(Date:10/13/2017)... ... October 13, 2017 , ... ... PharmD ‘17, and Jennifer Huggins, PharmD ’17, along with clinical associate professor ... prevention of cardiovascular diseases during the 15th Annual Women’s Health Conference. The ...
(Date:10/13/2017)... ... 2017 , ... Ellevate Network, the leading network for professional women, brought together ... equality at their inaugural Summit in New York City in June. The event was ... of over 3 million. To watch the Mobilize Women video, click here . ...
(Date:10/13/2017)... ... October 13, 2017 , ... “The Journey: From the Mountains to the ... save lost souls in the Philippines. “The Journey: From the Mountains to the Mission ... of the Bible. She has taught all ages and currently teaches a class of ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... the demand of today’s consumer and regulatory authorities worldwide. From Children’s to Adults ... tested to meet the highest standard. , These products are also: Gluten ...
Breaking Medicine News(10 mins):
(Date:10/2/2017)... Halo Labs announces the European launch of their new low volume, ... 2017 in Cambridge, U.K on October 4th. ... samples with unprecedented speed and sensitivity while using far less sample ... ... system ...
(Date:9/27/2017)... 27, 2017  Commended for their devotion to personalized service, ... as number one in the South Florida Business Journal,s 50 ... 5000 yearly list, the national specialty pharmacy has found its ... will soon be honored by SFBJ as the 2017 ... Set to receive his award in October, Bardisa said ...
(Date:9/23/2017)... Janssen Biotech, Inc. (Janssen) announced today that ... U.S. Food and Drug Administration (FDA) for the Biologics ... treatment of moderately to severely active rheumatoid arthritis (RA). ... needed to further evaluate the safety of sirukumab in ... "We are disappointed ...
Breaking Medicine Technology: