Navigation Links
Vigorous Exercise Aids Those With Obesity-Related Gene
Date:9/8/2008

Effect of mutation blunted in people with above-average activity scores, study finds

MONDAY, Sept. 8 (HealthDay News) -- Physical activity may reduce the risk of obesity in people with a genetic mutation that predisposes them to high body-mass index (BMI), says a U.S. study.

Recent research has shown a link between BMI and variants of the fat mass and obesity associated with the (FTO) gene. The mutations connected with obesity occur in about 30 percent of European populations and are associated with a 1.75-kilogram (3.9-lb.) increase in body weight, according to background information in the study.

While lifestyle factors such as diet and exercise are important factors in weight control, it's not exactly clear how they interact with genetics.

In this study, researchers analyzed DNA samples from 704 healthy Amish adults, average age 43.6, and also conducted a series of physiological tests on the participants, including recording their physical activity over a seven-day period.

Among the participants, 54 percent of men and 63.7 percent of women were overweight, and 10.1 percent of men and 30.5 percent of women were obese. The genetic analysis showed that 26 single-nucleotide polymorphisms (SNPs -- changes in a single base letter of DNA) in the FTO gene were associated with BMI.

Further investigation found that the two strongest SNPs were associated with BMI only in people with low physical activity scores. The SNPs had no effect on people with above-average physical activity scores.

The study was published in the Sept. 8 issue of the Archives of Internal Medicine.

"Activity levels in the 'high-activity' stratum were approximately 900 calories [860 calories for women and 980 calories for men] higher than in the 'low-activity' stratum, which, depending on body size, corresponds to about three to four hours of moderately intensive physical activity, such as brisk walking
'/>"/>

Copyright©2008 ScoutNews,LLC.
All rights reserved

Page: 1 2

Related medicine news :

1. Manor Care To Vigorously Contest TRO
2. More Sweat Equals Lower Risk of Exercise-Induced Asthma
3. Exercise May Help Prevent Age-Related Memory Loss
4. September 2008 Mayo Clinic Womens HealthSource Highlights Normal Weight Obesity, Regular Exercise and Cholesterol
5. Active Video Games Help Kids Exercise
6. Exercise Lowers Risk of Colon Cancer
7. Immigrant Children Less Likely to Exercise
8. Creatine Has Negligible Effect on COPD Exercise Rehab
9. No substitute for hard work: Creatine supplementation does not improve exercise outcomes in COPD
10. Exercise Testing for Cancer Fails to Follow Guidelines
11. Making patients move requires the right exercise advice
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/22/2014)... German . , ... their mode of action is complex: In low concentrations ... while at high concentrations they can cause "oxidative stress", ... redox signaling unfolds in single cells and organelles in ... jointly by the teams of LMU Professor Martin Kerschensteiner ...
(Date:4/22/2014)... (SALT LAKE CITY)A computational tool developed at the University ... with unknown gene mutations in three separate cases, U ... new study in The American Journal of Human ... Re-ranking tool), identifies undiagnosed illnesses and unknown gene mutations ... proteins that code for genes are made, in individual ...
(Date:4/22/2014)... nanodot technology, Berkeley Lab researchers have demonstrated the ... used to study the membranes of living cells. ... structures can reveal information critical to whether a ... cancerous, that can,t be obtained through conventional microscopy. ... provide a physical means to both probe and ...
(Date:4/22/2014)... -- In parallel with modern man ( Homo sapiens ), ... we lived side by side, such as Neanderthals and the ... sapiens survived. What was it in our genetic makeup ... little is known about our unique genetic makeup as distinguished ... fact that we are the only species among them ,to ...
(Date:4/22/2014)... may throw tantrums like toddlers, but their total ... say, a gerbil or fox squirrel, according to ... and birds ranging from orangutans to zebra finches. ... Yale and more than two-dozen other research institutions ... evolution of self-control, defined in the study as ...
Breaking Medicine News(10 mins):Health News:Neuroimaging: Live from inside the cell 2Health News:Applying math to biology: Software identifies disease-causing mutations in undiagnosed illnesses 2Health News:Applying math to biology: Software identifies disease-causing mutations in undiagnosed illnesses 3Health News:First size-based chromatography technique for the study of livi 2Health News:First size-based chromatography technique for the study of livi 3Health News:What gave us the advantage over extinct types of humans? 2Health News:Brain size matters when it comes to animal self-control 2Health News:Brain size matters when it comes to animal self-control 3
... NEW DELHI: The government of India has today assured that ... in the country // ,The government has ... eye on the on the domestic poultry population and migratory ... and take appropriate action as and when required. ...
... is to fund ?28m for research in United Kingdom ... for the eradication of Malaria worldwide. Bill Gates along ... three // international projects for malaria eradication over the ... funding is contributed to research of AIDS and cancer, ...
... there maybe gender difference of the risk of tobacco for ... at higher risk of developing the cancer. //, ... presented her findings at the 70th Annual Scientific Meeting ... smoking and alcohol use are well-established risk factors for colorectal ...
... Forest University Baptist Medical Center have found a new treatment ... found that the inactive form of EphA2 // protein in ... and the work was published in the Journal Molecular Cancer ... tumor and the least curable of all human cancers. ...
... to investigate the association among non-insulin-dependent diabetes, bone mineral ... that diabetic women have a higher bone mineral // ... between osteoporosis and cardiovascular risk factors in diabetics. , ... Type II diabetics have bone mass alterations and may ...
... is one of the most common cancers occurring in ... Eloxatin drug with other chemotherapeutic cancer drug for treatment ... reduced recurrence in these patients. This study which is ... Eloxatin with chemotherapeutic drugs more effective than control group ...
Cached Medicine News:Health News:Bill Gates to Fund ?28m for Malaria researc 2Health News:Women More Prone To Risk of Colorectal Cancer from Tobacco 2Health News:Protein Markers for Identification of Brain Tumor 2Health News:Diabetic Type II Women Have Elevated Bone Density Mass 2
(Date:1/15/2014)... , Jan. 15, 2014 As health officials across ... virus, select Meijer pharmacies in Michigan ... to eligible patients, enabling Meijer pharmacists to administer tests and, ... set by a physician participating in the study. ...
(Date:1/15/2014)... , Jan. 15, 2014  Celsion Corporation (the "Company") (NASDAQ: ... received commitments from institutional investors to purchase an aggregate ... in an at-the-market registered direct offering, led by a ... into definitive purchase agreements with these investors pursuant to ...
(Date:1/15/2014)...  Humberto C. Antunes,  Galderma  worldwide CEO, will receive a ... of Drugs in Dermatology (JDD) at the upcoming ... is January 17-20, 2014, at the Omni Orlando Resort at ChampionsGate ... The ODAC is a distinguished event that delivers a ...
Breaking Medicine Technology:Meijer Pharmacy Offers Free Flu, Strep Testing as Influenza Cases Rise Across the Midwest 2Meijer Pharmacy Offers Free Flu, Strep Testing as Influenza Cases Rise Across the Midwest 3Celsion Corporation Announces $15 Million At-The-Market Registered Direct Offering 2Celsion Corporation Announces $15 Million At-The-Market Registered Direct Offering 3Galderma's global leader honored with a "Lifetime in Dermatology Achievement Award" by Journal of Drugs in Dermatology 2Galderma's global leader honored with a "Lifetime in Dermatology Achievement Award" by Journal of Drugs in Dermatology 3Galderma's global leader honored with a "Lifetime in Dermatology Achievement Award" by Journal of Drugs in Dermatology 4
... 2011 BioSpecifics Technologies Corp. (Nasdaq: BSTC ... class collagenase-based products, today announced that its Board of ... the Company is authorized to repurchase up to $2 ... the Company,s continued commitment to increasing value for its ...
... 2011 Reportlinker.com announces that a new ... catalogue: Top Medical Devices ... http://www.reportlinker.com/p0558499/Top-Medical-Devices-and-Imaging-Technologies-2011.html?utm_source=prnewswire&utm_medium=pr&utm_campaign=Medical_Devices This research ... technologies that have excellent growth potential in ...
Cached Medicine Technology:BioSpecifics Technologies Corp. Announces Board Authorization of up to $2 Million Share Repurchase Program 2BioSpecifics Technologies Corp. Announces Board Authorization of up to $2 Million Share Repurchase Program 3Reportlinker Adds Top Medical Devices and Imaging Technologies 2011 2
Supplied sterile in peel-open packages. Intended for one-time use....
Used as a percutaneous entry needle to introduce wire guides. The coaxial design reduces potential A.V. malformations. Supplied sterile in peel-open packages. Intended for one-time use....
... affordable, high-quality light guide cables work in ... provide optimal brightness during a number of ... give you the flexibility and ease-of-use necessary ... is fully-autoclavable so they can be easily ...
ACMI™ offers an assortment of fiberoptic light guides, high transmission autoclavable fiberoptic light guides, and light guide adapters to connect our scopes to other manufacturers' light sourc...
Medicine Products: