Navigation Links
Video and Photo: Tasigna(R) Receives US Approval Providing New Hope to Chronic Myeloid Leukemia Patients With Resistance or Intolerance to Existing Therapies
Date:10/29/2007

ure should be monitored carefully, and any patient with signs or symptoms consistent with cardiac failure should be evaluated and treated.

Dose adjustments may be necessary due to hepatotoxicity, other nonhematologic adverse reactions, or hematologic adverse reactions. Therapy with Gleevec was discontinued for drug-related adverse reactions in 2.4% to 5% of patients.

A 25% decrease in the recommended dose should be used for patients with severe hepatic impairment.

Patients should be weighed and monitored regularly for signs and symptoms of edema, which can be serious or life-threatening. There have also been reports, including fatalities, of cardiac tamponade, cerebral edema, increased intracranial pressure, papilledema, and gastrointestinal (GI) perforation.

Bullous dermatologic reactions (eg, erythema multiforme and Stevens- Johnson syndrome) have also been reported. In some cases, the reaction recurred upon rechallenge. Several postmarketing reports describe patients able to tolerate the reintroduction of Gleevec at a lower dose with or without concomitant corticosteroids or antihistamines following resolution or improvement of the bullous reaction.

Consider potential toxicities-specifically liver, kidney, and cardiac toxicity, and immunosuppression from long-term use.

Gleevec is metabolized by the CYP3A4 isoenzyme and is an inhibitor of CYP3A4, CYP2D6, and CYP2C9. Dosage of Gleevec should increase by at least 50%, and clinical response should be carefully monitored, in patients receiving Gleevec with a potent CYP3A4 inducer such as rifampin or phenytoin. Examples of commonly used drugs that may significantly interact with Gleevec include ketoconazole, acetaminophen, warfarin, erythromycin, and phenytoin. (Please see full Prescribing Information for other potential drug interactions).

For daily dosing of 800 mg and above, dosing should be accomplished using the 400 mg tablet to reduce exposure to iron.

Common side e
'/>"/>

SOURCE Novartis
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8 9 10

Related medicine news :

1. Cut down TV and video games and you have less aggressive children.
2. Parents Should Beware of Violent Video Games
3. Children’s obesity linked to video game
4. Poland: Parental warning systems are likely to be adopted in video games.
5. Video Games, The Latest Craze Of American Adults
6. Interactive Video, Better Teaching Aid For Toddlers
7. Video Games Reduces Surgical Errors – A Stud
8. Fun And Cure With Video Games
9. Stroke Rehabilitation Through Modified Video Games
10. Videoconferencing, an impetus to Pediatric Oncology
11. Free Online Educational Videos for People with Diabetes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/22/2014)... The European Bio stimulants Market report defines ... analysis and forecast of revenue. The bio stimulants market ... million in 2013 to $940.6 million by 2018, at ... Browse through the TOC of the Europe Bio stimulants ... analysis provided. , http://www.micromarketmonitor.com/market/europe-bio-stimulants-1315565884.html , Agriculture contributes ...
(Date:7/22/2014)... 22, 2014 Alliance Storage ... data archiving solutions, has announced the availability of ... archiving solution. The unique new solution merges optical ... on compliant data archiving across all industries including ... The introduction of the new archiving tier permits ...
(Date:7/22/2014)... Murcia have studied the changes in the brain ... that causes difficulties in inhibiting a response in ... unplanned actions without considering the negative consequences. These ... the risk of behavioural problems. , A new ... Murcia analyses whether the connectivity of an infant,s ...
(Date:7/22/2014)... 22, 2014 There’s an old adage ... to the new improvements and enhancements Global Eyeglasses has ... to make lasting impressions while having what they need ... great, everyday. , “We are offering new sports clip ... said Arjun Sagar, CEO of Global Eyeglasses . ...
(Date:7/22/2014)... As part of a multinational, collaborative effort, ... Sinai have helped identify over 100 locations in the ... in the largest genomic study published on any psychiatric ... published online in Nature, point to biological mechanisms and ... new approaches to treating the disorder, which has seen ...
Breaking Medicine News(10 mins):Health News:Europe Bio Stimulants Market is Expected to Reach $940.6 Million in 2018 - New Report by MicroMarket Monitor 2Health News:Europe Bio Stimulants Market is Expected to Reach $940.6 Million in 2018 - New Report by MicroMarket Monitor 3Health News:Europe Bio Stimulants Market is Expected to Reach $940.6 Million in 2018 - New Report by MicroMarket Monitor 4Health News:Europe Bio Stimulants Market is Expected to Reach $940.6 Million in 2018 - New Report by MicroMarket Monitor 5Health News:Data Archiving Leader Alliance Storage Technologies Releases Enterprise Class Cloud-Integrated Storage Solution 2Health News:Data Archiving Leader Alliance Storage Technologies Releases Enterprise Class Cloud-Integrated Storage Solution 3Health News:Data Archiving Leader Alliance Storage Technologies Releases Enterprise Class Cloud-Integrated Storage Solution 4Health News:Children's impulsive behaviour is related to their brain connectivity 2Health News:Global Eyeglasses Adds New Products and Enhances Services 2Health News:Mount Sinai Scientists and International Team Shed New Light on Schizophrenia in Largest Genomic Study Published to Date 2Health News:Mount Sinai Scientists and International Team Shed New Light on Schizophrenia in Largest Genomic Study Published to Date 3Health News:Mount Sinai Scientists and International Team Shed New Light on Schizophrenia in Largest Genomic Study Published to Date 4
... there, experts warn , SUNDAY, Sept. 16 (HealthDay News) ... States occur at home but are preventable, according to ... From cleaning products to coat hangers, the average American ... accidents. Americans can take simple steps, such as wearing ...
... Lifestyle Experts - Plus TV Style, Expert ... Patients Through Live ... 15 People suffering from painful and,at times, embarrassing, ... Foundation officially launched the 2007 PATH program,-- Psoriatic Arthritis ...
... trouble, experts say , , SATURDAY, Sept. 15 (HealthDay News) -- ... or severe stomach pain is another matter that could signal ... People with the following symptoms need to see a doctor: ... pain lasting for hours or days; , pain that wakes ...
... 14 Aid provided by,The Prem Rawat Foundation has ... and their families who were victims of the flooding,earlier ... the flooding, caused by cyclones in this area last ... from their homes. The,Prem Rawat Foundation made a grant ...
... Ill., Sept. 14 The Board of,Directors of ... distributor and,supplier of disposable gloves and other products ... announced it would file a,Form 15 on or ... Exchange,Commission to deregister the Company,s common stock and ...
... HOUSTON, Sept. 14 The following is a,Statement by Oscar S. Wyatt, Jr.: "I,ve seen ... any politicians who want to,return those funds received from me, please return them in the form ... ... DeBakey Medical Foundation ...
Cached Medicine News:Health News:Eye Safety Begins at Home 2Health News:Empowerment Program Gets Patients on the PATH to Managing the Physical and Emotional Effects of Psoriatic Arthritis 2Health News:Empowerment Program Gets Patients on the PATH to Managing the Physical and Emotional Effects of Psoriatic Arthritis 3Health News:The Prem Rawat Foundation Supports Disaster-Relief Efforts in Mozambique 2Health News:AHPC Holdings, Inc. Announces Intent to Deregister Common Stock With Securities and Exchange 2
(Date:7/22/2014)... 2014 The steady decline of pharmaceutical ... previously rep-friendly specialties, according to the spring 2014 ... firm ZS Associates.      AccessMonitor™ aggregates ... sales teams. The report examines how often approximately ... pharmaceutical sales reps who visit their offices. ...
(Date:7/22/2014)... , July 22, 2014 BioDelivery Sciences ... that its Board of Directors has appointed Charles ... Feinberg as members of the Board.  ... with extensive experience in marketing, sales and other commercial ... Pearl Therapeutics, Inc., a development stage company that was ...
(Date:7/22/2014)... , July 22, 2014  UL (Underwriters ... that the U.S. Food and Drug Administration (FDA) ... consensus standards for medical devices incorporating lithium or ... - Standard for Household and Commercial Batteries, and ... Consensus standards are standards recognized ...
Breaking Medicine Technology:Even traditionally rep-friendly specialists will see fewer pharmaceutical sales reps this year, according to ZS Associates 2Even traditionally rep-friendly specialists will see fewer pharmaceutical sales reps this year, according to ZS Associates 3Even traditionally rep-friendly specialists will see fewer pharmaceutical sales reps this year, according to ZS Associates 4Even traditionally rep-friendly specialists will see fewer pharmaceutical sales reps this year, according to ZS Associates 5BioDelivery Sciences Appoints Charles J. Bramlage and Dr. Barry I. Feinberg to its Board of Directors 2BioDelivery Sciences Appoints Charles J. Bramlage and Dr. Barry I. Feinberg to its Board of Directors 3BioDelivery Sciences Appoints Charles J. Bramlage and Dr. Barry I. Feinberg to its Board of Directors 4BioDelivery Sciences Appoints Charles J. Bramlage and Dr. Barry I. Feinberg to its Board of Directors 5BioDelivery Sciences Appoints Charles J. Bramlage and Dr. Barry I. Feinberg to its Board of Directors 6BioDelivery Sciences Appoints Charles J. Bramlage and Dr. Barry I. Feinberg to its Board of Directors 7Two UL Battery Safety Standards Are now FDA Recognized Consensus Standards for Medical Devices 2
The only daily cleaner specially formulated with isopropyl alcohol to help dissolve lipids and oil-based make-up from contact lenses....
Clerz Plus helps retain moisture to relieve dryness and removes protein buildup from your lenses while you wear them for longer wear comfort....
Lens Plus rewetting drops for soft contact lenses....
... Renu Multiplus preservative free lubricating ... moisturize your eyes while you're ... gentle preservative free formula is ... be sensitive to preservatives and ...
Medicine Products: