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Video and Photo: Tasigna(R) Receives US Approval Providing New Hope to Chronic Myeloid Leukemia Patients With Resistance or Intolerance to Existing Therapies
Date:10/29/2007

sed portfolio, which is focused on strategic growth platforms in innovation-driven pharmaceuticals, high-quality and low-cost generics, human vaccines and leading self-medication OTC brands. Novartis is the only company with leadership positions in these areas. In 2006, the Group's businesses achieved net sales of USD 37.0 billion and net income of USD 7.2 billion. Approximately USD 5.4 billion was invested in R&D. Headquartered in Basel, Switzerland, Novartis Group companies employ approximately 100,000 associates and operate in over 140 countries around the world. For more information, please visit http://www.novartis.com.

References:

(1) American Cancer Society. Overview: Leukemia - Chronic Myeloid (CML). http://www.cancer.org/docroot/CRI/content/CRI_2_2_1x_How_Many_People_Get_Ch ron ic_Myeloid_Leukemia.asp?rnav=cri Last accessed October, 2007.

(2) Faderl S; Talpaz M; Estrov Z; O'Brien S; Kurzrock R; Kantarjian HM.

The biology of chronic myeloid leukemia. N Engl J Med. 341:164-72,

1999.

(3) Druker, B. et al. Five-Year Follow-up of Patients Receiving Imatinib

for Chronic Myeloid Leukemia. N Engl J Med 2006;355:2408-17.

(4) Gleevec(R) (imatinib mesylate) tablets prescribing information. East

Hanover, NJ: Novartis Pharmaceuticals Corporation; Sep 2007.

* Known as Glivec(R) (imatinib) outside the US, Canada and Israel.

** Numbers indicate the range of percentages in 4 studies among adult

patients with Ph+ CML in blast crisis, accelerated phase, and chronic

phase.

+ For more detailed study information please see full Prescribing

Information.


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