Navigation Links
Video: Phase III Head to Head Trial Showed Ticagrelor Reduced Cardiovascular Death and Heart Attacks Over Clopidogrel in Acute Coronary Syndromes Patients
Date:8/29/2009

e composite of myocardial infarction, stroke, and all-cause mortality. Among patients who received a stent during the study, a 33% reduction in risk of definite stent thrombosis was achieved with ticagrelor.

"The goal of new antiplatelet therapies is to improve the efficacy for patients without increasing the associated risks of treatment such as bleeding. Ticagrelor achieved a significant reduction in CV mortality in ACS patients versus clopidogrel and importantly without an increase in major bleeding," commented Professor Lars Wallentin, co-chair of the PLATO Executive Committee, Uppsala Clinical Research Centre.

AstraZeneca Executive Vice-President Development, Anders Ekblom said, "The PLATO study was designed to reflect how patients with ACS are currently managed in clinical practice, by including patients who underwent invasive procedures and those who were managed with medication only. The PLATO data suggest ticagrelor could be a valuable new option for a broad range of acute coronary syndromes patients. We look forward to filing BRILINTA with regulatory authorities in the fourth quarter."

The PLATO study confirmed the clinical safety profile of previous ticagrelor studies which showed no difference in major bleeding compared to clopidogrel. When PLATO minor bleeding was added to the major bleeding results, ticagrelor showed an increase versus clopidogrel (16.1% vs. 14.6%, p=0.008). There was also an increase in non-procedural related bleeding with ticagrelor. Within the patient subgroups of gender, weight, history of stroke/TIA, ticagrelor showed no increase in the incidence of major bleeding versus clopidogrel.

Consistent with phase II data, ventricular pauses (slowing of heart rhythms) occurred more often with ticagrelor but without associated symptoms or clinical consequences for the patient. Dyspnoea was reported more frequently by patients on ticagrelor (13.8% vs. 7.8%, p < 0.
'/>"/>

SOURCE AstraZeneca
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related medicine news :

1. Video: AstraZeneca Traveling Exhibit Helps Americans Understand and Manage Bipolar Depression
2. Video: School Nurses Tackle Low Parental Awareness of Meningitis Via Comprehensive National Public Education Campaign
3. Video: Sounds of Pertussis Campaign Urges Adults to Take Action During National Immunization Awareness Month
4. Video: Schering-Plough Announces FDA Approval of SAPHRIS(R) (asenapine) for Acute Treatment of Schizophrenia In Adults and Manic or Mixed Episodes of Bipolar I Disorder With or Without Psychotic Features In Adults
5. Video: FDA Approves EMBEDA(TM) For Management of Moderate to Severe Chronic Pain
6. Video: Provectus Pharmaceuticals Updates Shareholders On 2009 Year-To-Date Accomplishments
7. Video: People With Pain, Healthcare Providers Sound Off in First-Ever Online Talk Show About Pain
8. Video: American Dental Association Statement: Food and Drug Administration Action on Dental Amalgam
9. Video: Sodexo Takes on Childhood Obesity in School Cafeterias
10. Video: What Are Those Little Red Bumps?
11. Video: Perot Systems Unveils Series of Healthcare Video Case Studies
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/25/2015)... New York (PRWEB) April 25, 2015 ... established for vaginal mesh lawsuits filed against C.R. ... U.S. District Court, Southern District of West Virginia. ... a Scheduling Conference was convened that day, after ... Master Long Form Complaint. The Order directed that ...
(Date:4/25/2015)... 25, 2015 The impact of the ... the excitement of the public and is likely to ... of May and June. From March 21st to ... tradition of "Special Prayers." More than 600 people participated ... Special Prayers and have reported intense experiences that they ...
(Date:4/25/2015)... (PRWEB) April 25, 2015 Parker and Sons ... and cooling, has spiked in Arizona alongside the growing economy. ... additional forty employees for April to help account for the ... forty employees in April is something we are enthusiastic about. ... said Paul Kelly, president at Parker and Sons. , Indeed, ...
(Date:4/25/2015)... 25, 2015 On Friday, April 17, ... Journal’s annual Best Implementation Award. This award is ... best use of RFID technology to improve its manufacturing, ... company that best demonstrates how RFID is delivering real ... RFID Journal Live! 2015 in San Diego, the RFID ...
(Date:4/24/2015)... Constellations Recovery celebrates the opening of the ... 35 miles from New York City, Constellations Recovery was ... while recovering from addiction. The Open House, which is ... doctors and treatment centers to see the residence, tour ... offered by Constellations Recovery.,  , The newly opened facility ...
Breaking Medicine News(10 mins):Health News:C.R. Bard Vaginal Mesh Lawsuit News: Federal Litigation Issues New Pretrial Order Following Submission of Amended Responses to Master Complaint 2Health News:C.R. Bard Vaginal Mesh Lawsuit News: Federal Litigation Issues New Pretrial Order Following Submission of Amended Responses to Master Complaint 3Health News:C.R. Bard Vaginal Mesh Lawsuit News: Federal Litigation Issues New Pretrial Order Following Submission of Amended Responses to Master Complaint 4Health News:Trivedi Master Wellness™ Announces the Resounding Success of their Special Prayers Human Wellness Program 2Health News:Trivedi Master Wellness™ Announces the Resounding Success of their Special Prayers Human Wellness Program 3Health News:Parker and Sons Plans to Expand in 2015 2Health News:Seeonic’s Industry Leading Technology Powers Interstate Batteries to Winning Award 2Health News:Constellations Recovery Opens The First Luxury Sober Living Residence in Westchester New York 2Health News:Constellations Recovery Opens The First Luxury Sober Living Residence in Westchester New York 3
... ... announced that nine distinguished scientists have joined its Environmental Task Force to explore possible ... IDA also announced the members of the Task Force’s Steering Committee as well as ... ...
... ... for military veterans harmed by Agent Orange. , ... Parkersburg, WV (PRWEB) April 24, 2010 -- According to attorney Jan ... and ischemic heart disease should have an easier time obtaining disability benefits under a recently ...
... for American adults have stabilized while the rate of childhood ... the journal Medical Decision Making , published by SAGE. ... from 2000-2004 and validated against 2005-2006 data, the study looked ... in the United States. The research explored statistics for many ...
... yielded best results when put in those younger ... News) -- Inserting cochlear implants early significantly improves ... who have severe hearing loss, a new study ... three years in 188 children who underwent cochlear ...
... to live together happily, experts say , FRIDAY, April 23 ... to cats, enduring regular bouts of congestion, sneezing, and watery ... as an office manager for a feline veterinary hospital in ... "They showed up and never left so I took them ...
... ... Research Council , low reimbursements from public health insurance programs, such as Medicare and Medicaid, ... forcing auto insurers to more closely scrutinize and negotiate hospital bills prior to payment. ... Malvern, PA (Vocus) April ...
Cached Medicine News:Health News:International Desalination Association Announces Members of Environmental Task Force and Dates for Environmental Symposium 2Health News:International Desalination Association Announces Members of Environmental Task Force and Dates for Environmental Symposium 3Health News:International Desalination Association Announces Members of Environmental Task Force and Dates for Environmental Symposium 4Health News:International Desalination Association Announces Members of Environmental Task Force and Dates for Environmental Symposium 5Health News:International Desalination Association Announces Members of Environmental Task Force and Dates for Environmental Symposium 6Health News:International Desalination Association Announces Members of Environmental Task Force and Dates for Environmental Symposium 7Health News:New Disability Benefits Could Soon Be Available to Vietnam Vets 2Health News:New Disability Benefits Could Soon Be Available to Vietnam Vets 3Health News:Early Surgery Best for Children With Hearing Loss 2Health News:Cat Allergy Doesn't Have to Mean Giving Up Kitty 2Health News:Cat Allergy Doesn't Have to Mean Giving Up Kitty 3Health News:Hospital Cost Shifting Adds to Auto Injury Claim Costs 2Health News:Hospital Cost Shifting Adds to Auto Injury Claim Costs 3Health News:Hospital Cost Shifting Adds to Auto Injury Claim Costs 4
(Date:4/24/2015)... DUBLIN , Apr. 24, 2015 /PRNewswire/ ... ) has announced the addition of the ... Printer/ Pipette tips/ Pumps/Microplate/Reagent Reservoir/Valve/Tubing/Wash Station) & ... Institute) - Global Forecast to 2020" ... global laboratory accessories market is expected to ...
(Date:4/24/2015)... -- Novartis Pharmaceuticals Corporation (NPC) has been named the top company ... the annual DiversityInc Top 50 Companies for Diversity listing. DiversityInc ... Diversity on April 23 at an awards ceremony in ... on the DiversityInc Top 10 Companies for Recruitment list and ... list. David Epstein , Division Head, ...
(Date:4/24/2015)... Ga. , April 24, 2015 ... researchers, paper, that such was not the product of reliable ... form a reliable basis for allegations of adulteration. ... position on a false premise, or misguided hope, ... fact, these studies are contradicted by multiple other ...
Breaking Medicine Technology:Global Lab Accessories Market Report 2015-2020 - Label Printer/ Pipette tips/ Pumps/Microplate/Reagent Reservoir/Valve/Tubing/Wash Station 2Global Lab Accessories Market Report 2015-2020 - Label Printer/ Pipette tips/ Pumps/Microplate/Reagent Reservoir/Valve/Tubing/Wash Station 3Novartis Pharmaceuticals Corporation is first company to receive number one ranking two years in a row on DiversityInc Top 50 Companies for Diversity list 2Novartis Pharmaceuticals Corporation is first company to receive number one ranking two years in a row on DiversityInc Top 50 Companies for Diversity list 3Novartis Pharmaceuticals Corporation is first company to receive number one ranking two years in a row on DiversityInc Top 50 Companies for Diversity list 4Hi-Tech Responds to "Bullying Tactics" Issued by FDA on Acacia Rigidula 2Hi-Tech Responds to "Bullying Tactics" Issued by FDA on Acacia Rigidula 3Hi-Tech Responds to "Bullying Tactics" Issued by FDA on Acacia Rigidula 4Hi-Tech Responds to "Bullying Tactics" Issued by FDA on Acacia Rigidula 5Hi-Tech Responds to "Bullying Tactics" Issued by FDA on Acacia Rigidula 6
... VALENCIA, Calif., Oct. 4, 2011 Bioness ... initial enrollment phase of the FASTEST study to further examine ... individuals with foot drop as a result of stroke. The ... L300® Foot Drop System over standard therapy with an ankle-foot ...
... Goldfarb Branham LLP is investigating whether ... PPDI ) violated shareholder protection laws by ... Concerned investors are encouraged to contact attorney Hamilton Lindley ... and remedies. "As recently as mid-August, ...
Cached Medicine Technology:Bioness Inc. Announces Completion of Enrollment in Its FASTEST L300 Study 2
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: