Navigation Links
Viagra could reduce multiple sclerosis symptoms
Date:5/19/2011

Universitat Autnoma de Barcelona researchers have discovered that Viagra drastically reduces multiple sclerosis symptoms in animal models with the disease. The research, published in Acta Neuropathologica, demonstrates that a practically complete recovery occurs in 50% of the animals after eight days of treatment. Researchers are confident that clinical trials soon will be carried out in patients given that the drug is well tolerated and has been used to treat sexual dysfunction in some multiple sclerosis patients.

Multiple sclerosis is the most common chronic inflammatory disease of the central nervous system and one of the main causes of disability among young adults. The disease is caused by the presence of multiple focuses of demyelination (loss of myelin sheaths around the axons, affecting the ability of neurons to communicate) and neurodegeneration in different areas of the central nervous system. There is currently no cure for the disease, although some drugs have proven effective in fighting symptoms and preventing it from progressing.

A research team from the UAB Institute of Biotechnology and Biomedicine directed by Dr Agustina Garca, in collaboration with the research team directed by Dr Juan Hidalgo from the UAB Institute of Neurosciences, has studied the effects of a treatment using sildenafil, sold as Viagra, in an animal model of multiple sclerosis known as experimental autoimmune encephalomyelitis (EAE). Researchers demonstrated that a daily treatment with sildenafil after disease onset quickly reduced clinical signs, with a practically complete recovery in 50% of the cases after eight days of treatment. Scientists observed how the drug reduced the infiltration of inflammatory cells into the white matter of the spinal cord, thus reducing damage to the nerve cell's axon and facilitating myelin repair.

Sidenafil, together with tadalafil (Cialis) and vardenafil (Levitra), form part of a group of vasodilator drugs known as phosphodiesterase type 5 (PDE5) inhibitors, used in the treatment of erectile dysfunction and pulmonary arterial hypertension. Recent studies in animal models of central nervous system pathologies already pointed to the fact that in addition to vasodilation, these drugs could contain other neuroprotective actions and suggest their usefulness as possible treatments of both acute (cerebrovascular stroke) and chronic (Alzheimer's) neuropathologies. In fact, in a research published in 2010 in the Journal of Neurochemistry, the same research group from UAB demonstrated that one of these inhibitors reduced neuroinflammation and neuronal damage in animal models of traumatic brain injury.


'/>"/>

Contact: Agustina Garcia
Agustina.garcia@uab.cat
34-935-812-802
Universitat Autonoma de Barcelona
Source:Eurekalert  

Related medicine news :

1. Pediatricians Want to Restrict Ads for Tobacco, Booze, Viagra
2. Drugs Like Viagra Linked to Higher Rates of STDs
3. FDA Panel Votes Against Approval of Female Viagra
4. FDA Panel Weighs OK of Female Viagra
5. Viagra Linked to Hearing Loss
6. Viagra May Aid Those With Lung Fibrosis
7. UAB study examines hearing loss, Viagra use
8. Study Explores Possibility of a Female Viagra
9. Implant jab could solve the misery of back pain
10. Simple fitness test could predict long-term risk for heart attack, stroke in middle-aged people
11. Half of prostate cancers could potentially benefit from new type of cancer drugs, U-M study finds
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Viagra could reduce multiple sclerosis symptoms
(Date:1/19/2017)... ... January 19, 2017 , ... ... of Proctology) announced today the opening of 3 medical offices specializing specifically ... Hemorrhoids Center of Los Angeles (Beverly Hills), Hemorrhoids Center of Newport Beach, ...
(Date:1/18/2017)... ... , ... A recent video posting of a new fidget product gathered online ... to relieve stress and anxiety. No one was more surprised than Think Ink ... completed a successful Kickstarter campaign raising $67,000 on the popular crowdfunding platform. “We’ve ...
(Date:1/18/2017)... ... January 18, 2017 , ... From a health perspective, 2017 ... daily linking gut health to chronic disease, mental health and general physical well-being. The ... an important resolution to consider. , For one Charlottesville restaurant, good gut health is ...
(Date:1/18/2017)... ... January 18, 2017 , ... The VA Maryland Health ... on a research project focused on multiple sclerosis (MS). Led by Christopher M. ... to control the disease without compromising normal immune function that often occurs during ...
(Date:1/18/2017)... ... January 18, 2017 , ... ... among specialty pharmacists and pharmacy professionals, has teamed up with Ochsner Health ... program, announced Brian Haug, president of Pharmacy Healthcare Communications, LLC, publishers of ...
Breaking Medicine News(10 mins):
(Date:1/19/2017)... , January 19, 2017 According to ... for cryotherapy is set to witness a CAGR of 6.5% during ... America will continue to be the leading market for ... ... Suppliers are emphasizing on ensuring affordable and adequate supply of gas ...
(Date:1/19/2017)... 2017 Accuray Incorporated (Nasdaq: ARAY ... continue to set the bar for excellence in customer ... user satisfaction rating among radiation treatment delivery systems in ... Market Intelligence Briefing™. The most recent ratings trend also ... industry peers for 11 of the past 12 quarters. ...
(Date:1/19/2017)... Calif. , Jan. 19, 2017  Abaxis, Inc. ... manufacturing point-of-care blood analysis instruments and consumables for the ... call to discuss its financial results for the third ... call will be at 4:15 p.m. ET on Thursday, ... for the third quarter fiscal year 2017 after the ...
Breaking Medicine Technology: