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Veterinary researchers study poultry virus as human cancer treatment
Date:2/12/2008

According to Subbiah, the use of poultry viruses as cancer therapy poses no threat to humans and several other oncolytic viruses are currently being explored to treat cancer. However, Subbiahs work is the first to alter the Newcastle disease virus through a reverse genetic system for selective protease targeting. Oncolytic virus therapy has gained much attention recently as a result of the progress in understanding virus-host interactions and because currently available chemotherapy is not entirely satisfactory for several reasons, including the possibility of an individuals development of resistance to drugs.

We are excited about the endless possibilities that Newcastle disease virus offers to treat cancer, said Subbiah.

This is the second major grant awarded to the researchers for the work aiming to create a cancer therapy from genetically altered Newcastle Disease virus.

Subbiah received his bachelors degree in veterinary science in 1984, masters degree in veterinary science in 1989, and Ph.D. in veterinary microbiology in 1996 from the Madras Veterinary College in Madras, India; and he was boarded in virology from the American College of Veterinary Microbiologists in 2003. He was a research assistant professor at the Virginia-Maryland Regional College of Veterinary Medicines College Park, Md., campus prior to joining Virginia Tech in 2006.

Samal received his bachelors degree in veterinary science from Orissa Veterinary College (India) in 1976, his masters degree in veterinary science from the Indian Veterinary Research Institute, and master of science and Ph.D. degrees from Texas A&M University. He joined the faculty at the University of Maryland in 1988, and is currently the associate dean of the Virginia-Maryland Regional College of Veterinary Medicine and chair of the Department of Veterinary Medicine at the University of Maryland in College Park.


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Contact: Christy Jackson
cljacks@vt.edu
540-231-7239
Virginia Tech
Source:Eurekalert

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